Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jan H. Driller"'
Autor:
Nikolai Tschernoster, Florian Erger, Stefan Kohl, Björn Reusch, Andrea Wenzel, Stephen Walsh, Holger Thiele, Christian Becker, Marek Franitza, Malte P. Bartram, Martin Kömhoff, Lena Schumacher, Christian Kukat, Tatiana Borodina, Claudia Quedenau, Peter Nürnberg, Markus M Rinschen, Jan H. Driller, Bjørn P. Pedersen, Karl P. Schlingmann, Bruno Hüttel, Detlef Bockenhauer, Bodo Beck, Janine Altmüller
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-17 (2023)
Abstract Background Long-read sequencing is increasingly used to uncover structural variants in the human genome, both functionally neutral and deleterious. Structural variants occur more frequently in regions with a high homology or repetitive segme
Externí odkaz:
https://doaj.org/article/562f2d8f33f64894b552c46d64c66672
Autor:
Matthias Siebert, Mathias A Böhme, Jan H Driller, Husam Babikir, Malou M Mampell, Ulises Rey, Niraja Ramesh, Tanja Matkovic, Nicole Holton, Suneel Reddy-Alla, Fabian Göttfert, Dirk Kamin, Christine Quentin, Susan Klinedinst, Till FM Andlauer, Stefan W Hell, Catherine A Collins, Markus C Wahl, Bernhard Loll, Stephan J Sigrist
Publikováno v:
eLife, Vol 4 (2015)
Synaptic vesicles (SVs) fuse at active zones (AZs) covered by a protein scaffold, at Drosophila synapses comprised of ELKS family member Bruchpilot (BRP) and RIM-binding protein (RBP). We here demonstrate axonal co-transport of BRP and RBP using intr
Externí odkaz:
https://doaj.org/article/cc5f709ea3a149bb840b71b1ba400d10
Autor:
Markus C. Wahl, Ulrich Stelzl, Sunbin Liu, Stephan J. Sigrist, Martin Lehmann, Janine Lützkendorf, Astrid G. Petzoldt, Benno Kuropka, Vladimir Ugorets, Bernhard Loll, Christine B. Beuschel, Niraja Ramesh, Christian Freund, Torsten W.B. Götz, Elena Knoche, Suneel Reddy-Alla, Jan H. Driller, Sara Mertel, Fan Liu, Tanja Matkovic-Rachid
Publikováno v:
The Journal of Cell Biology
The journal of cell biology 219(7), e201902059 (2020). doi:10.1083/jcb.201902059
The journal of cell biology 219(7), e201902059 (2020). doi:10.1083/jcb.201902059
Petzoldt et al. investigate the functional protein architecture at the presynaptic active zone, an elaborate protein scaffold organizing synaptic vesicle (SV) release. They find that the conserved multidomain protein RIM-BP provides a relay to guide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948e8ac8657ae792620e23b748e81ed2
http://www.helmholtz-berlin.de/pubbin/oai_publication?VT=1&ID=102723
http://www.helmholtz-berlin.de/pubbin/oai_publication?VT=1&ID=102723
Phosphorylation of the Bruchpilot N-terminus unlocks axonal transport of active zone building blocks
Autor:
Ulrich Stelzl, Benno Kuropka, Martin Lehmann, Jan H. Driller, Albert Sickmann, Markus C. Wahl, Christoph Weise, Christian Freund, Janine Lützkendorf, René P. Zahedi, Astrid G. Petzoldt, Stephan J. Sigrist, Matthias Siebert, Chengji Piao, Harald Depner
Publikováno v:
Journal of Cell Science.
Protein scaffolds at presynaptic active zone membranes control information transfer at synapses. For scaffold biogenesis and maintenance, scaffold components must be safely transported along axons. A spectrum of kinases was suggested to control trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce71bd375c56a570b5e46560071b23de
https://doi.org/10.1242/jcs.225151
https://doi.org/10.1242/jcs.225151
Autor:
Jan H, Driller, Janine, Lützkendorf, Harald, Depner, Matthias, Siebert, Benno, Kuropka, Christoph, Weise, Chengji, Piao, Astrid G, Petzoldt, Martin, Lehmann, Ulrich, Stelzl, René, Zahedi, Albert, Sickmann, Christian, Freund, Stephan J, Sigrist, Markus C, Wahl
Publikováno v:
Journal of cell science. 132(6)
Protein scaffolds at presynaptic active zone membranes control information transfer at synapses. For scaffold biogenesis and maintenance, scaffold components must be safely transported along axons. A spectrum of kinases has been suggested to control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5260da32f02c66511eaa1ab4e297893c
https://pubmed.ncbi.nlm.nih.gov/30745339
https://pubmed.ncbi.nlm.nih.gov/30745339
Autor:
Jana Sticht, Bernhard Loll, Markus C. Wahl, Benno Kuropka, Christian Freund, Fabian Gerth, Xiao Jakob Schmitt, Kevin Pagel, Jan H. Driller, Maria Jäpel, Volker Haucke
Publikováno v:
Structure (London, England : 1993). 27(6)
Summary The scaffolding protein intersectin 1 plays important roles in clathrin-mediated endocytosis and in the replenishment of release-ready synaptic vesicles (SV). Two splice variants of intersectin's SH3A domain are expressed in the brain, and as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3070c4a6e70433515d2df5048ecd002d
https://pubmed.ncbi.nlm.nih.gov/31031201
https://pubmed.ncbi.nlm.nih.gov/31031201
Autor:
Cahir J. O'Kane, Mathias A. Böhme, Jan H. Driller, Iain M. Robinson, Christina Beis, Markus C. Wahl, Ulrich Stelzl, Malou M. Mampell, Eric Reynolds, Husam Babikir, Alexander M. Walter, Dominique Dufour Bergeron, Stefan W. Hell, Bernhard Loll, Stephan J. Sigrist, Janine Lützkendorf, Andreas T. Grasskamp, Suneel Reddy-Alla, Fabian Göttfert
Publikováno v:
Nature Neuroscience
Brain function relies on fast and precisely timed synaptic vesicle (SV) release at active zones (AZs). Efficacy of SV release depends on distance from SV to Ca(2+) channel, but molecular mechanisms controlling this are unknown. Here we found that dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65c6b7d1b101d7ce13f9b660cca900b
https://hdl.handle.net/11858/00-001M-0000-002C-674B-611858/00-001M-0000-002C-674A-811858/00-001M-0000-002C-6749-A11858/00-001M-0000-002B-2236-2
https://hdl.handle.net/11858/00-001M-0000-002C-674B-611858/00-001M-0000-002C-674A-811858/00-001M-0000-002C-6749-A11858/00-001M-0000-002B-2236-2
Autor:
Christine Quentin, Catherine A. Collins, Malou M. Mampell, Husam Babikir, Ulises Rey, Stephan J. Sigrist, Niraja Ramesh, Jan H. Driller, Nicole Holton, Suneel Reddy-Alla, Markus C. Wahl, Matthias Siebert, Fabian Göttfert, Bernhard Loll, Susan Klinedinst, Stefan W. Hell, Tanja Matkovic, Mathias A. Böhme, Till Fm M. Andlauer, Dirk Kamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4783e37897d608faf2fe93228d241917
https://doi.org/10.7554/elife.06935.026
https://doi.org/10.7554/elife.06935.026
Autor:
Fabian Goettfert, Stephan J. Sigrist, Markus C. Wahl, Suneel Reddy-Alla, Ulises Rey, Karzan Muhammad, Bernhard Loll, Peter Scheiffele, Jan Schmoranzer, Niraja Ramesh, Mathias A. Böhme, Alexander M. Walter, Jan H. Driller, Dietmar Schreiner, Dominique Dufour Bergeron, Torsten W.B. Götz, Tanja Matkovic, Janine Lützkendorf, Harald Depner, Christina Hollmann, Stefan W. Hell, Matthew Holt
Publikováno v:
Nature Communications, 6: 8362
Nature Communications
Nature Communications
Assembly and maturation of synapses at the Drosophila neuromuscular junction (NMJ) depend on trans-synaptic neurexin/neuroligin signalling, which is promoted by the scaffolding protein Syd-1 binding to neurexin. Here we report that the scaffold prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57fdbaa8c07520ab7609b1643bbb7d1
https://edoc.unibas.ch/39909/
https://edoc.unibas.ch/39909/
Autor:
Markus C. Wahl, Jennifer A. Lardong, Harald Depner, Stephan J. Sigrist, Christoph Weise, Astrid G. Petzoldt, Bernhard Loll, Jan H. Driller
Rab GTPases belong to the large family of Ras proteins. They act as key regulators of membrane organization and intracellular trafficking. Functionally, they act as switches. In the active GTP-bound form they can bind to effector proteins to facilita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1110243bf61df93970ef4a03af0768c
https://europepmc.org/articles/PMC4304744/
https://europepmc.org/articles/PMC4304744/