Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jan H. Brakkee"'
Publikováno v:
European Journal of Pharmacology. 719:192-201
Decades ago it was recognized that the pharmacological profile of melanocortin ligands that stimulated grooming behavior in rats was strikingly similar to that of Xenopus laevis melanophore pigment dispersion. After cloning of the melanocortin MC1 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdae5a05074149f4dea056653b48629b
https://doi.org/10.1016/j.ejphar.2013.04.060
https://doi.org/10.1016/j.ejphar.2013.04.060
Autor:
Ruben van Boxtel, Dylan J. M. Bergen, Roger A.H. Adan, Keith M. Garner, Joram D. Mul, Maike A.D. Brans, Edwin Cuppen, Pim W. Toonen, Jan H. Brakkee
Publikováno v:
Obesity, 20(3), 612-621. Wiley-Blackwell
Obesity (Silver Spring, Md.)
Obesity (Silver Spring, Md.)
Obesity is caused by an imbalance between energy intake and expenditure and has become a major health-care problem in western society. The central melanocortin system plays a crucial role in the regulation of feeding and energy expenditure, and funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad522f32ac0212eb858d266e03f56d1
https://doi.org/10.1038/oby.2011.81
https://doi.org/10.1038/oby.2011.81
Publikováno v:
Physiology & Behavior. 85:151-157
Activity-based anorexia (ABA) is considered an animal model of anorexia nervosa. In ABA, scheduled feeding in combination with voluntary wheel running leads to hyperactivity, reduced food intake, severe body weight loss and hypothermia. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b560b471a27e5fbc861382e2cb931255
https://doi.org/10.1016/j.physbeh.2005.03.017
https://doi.org/10.1016/j.physbeh.2005.03.017
Publikováno v:
Neuroscience. 125:645-650
The adult peripheral nervous system is able to regenerate after injury. Regeneration is associated with the expression of new genes and proteins. Proteins abundant in developing axons increase in expression after injury, whereas proteins involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b2864a052810772dfbc9ffb13f350e
https://doi.org/10.1016/j.neuroscience.2004.02.006
https://doi.org/10.1016/j.neuroscience.2004.02.006
Autor:
Marco F.M. Hoekman, Simone M. Smits, Christina F. Vogelaar, Willem Hendrik Gispen, L.H. Schrama, J. Peter H. Burbach, Jan H. Brakkee, Marten P. Smidt
Publikováno v:
Neuroscience Research Communications. 32:49-59
Homeobox genes encode transcription factors that play key roles in embryonic development of the nervous system. Dorsal root ganglia are part of the peripheral nervous system that arises from the neural crest. Several homeobox genes are known to play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::265c179823731ced352f514b198a4606
https://doi.org/10.1002/nrc.10058
https://doi.org/10.1002/nrc.10058
Autor:
Geoffrey van der Plasse, Linda W. M. van Kerkhof, Jan H. Brakkee, Martien J H Kas, Rolf Struikmans, Ria de Haas, Herman G.M. Westenberg
Publikováno v:
Journal of neuroscience methods. 209(1)
Although deep brain stimulation (DBS) has been proven to be an effective treatment for several neuropsychiatric disorders, such as Parkinson's disease, the underlying working mechanisms are still largely unknown. Behavioral animal models are essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8590f2567c456514ccf8d8b6efbedff2
https://pubmed.ncbi.nlm.nih.gov/22677175
https://pubmed.ncbi.nlm.nih.gov/22677175
Autor:
Geert Jan Biessels, W.H. Gispen, Jan H. Brakkee, A.C. Kappelle, Paul J. M. Helders, N.L.U. Meeteren
Publikováno v:
Restorative neurology and neuroscience. 10(2)
The effect of moderate exercise training on acute and chronic neuropathy in two separate experiments was examined. Acute nerve dysfunction was induced by sciatic nerve crush lesion and chronic neuropathy by streptozotocin-induced diabetes mellitus (e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a510cc40b04d4c85b21367a7362b9f
https://pubmed.ncbi.nlm.nih.gov/21551857
https://pubmed.ncbi.nlm.nih.gov/21551857
Autor:
N.G.M. Schipper, Willem Hendrik Gispen, Stefan Romeijn, Frans W. H. M. Merkus, Victor M. Wiegant, J. Coos Verhoef, Larissa M. De Lannoy, Jan H. Brakkee
Publikováno v:
British Journal of Pharmacology. 110:1335-1340
1. The systemic absorption and the neurotrophic effect of the metabolically stabilized ACTH (4-9) analogue, Org2766, were investigated following intranasal (i.n.) administration. 2. Without additives the nasal bioavailability of the peptide was in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79c87ff30a2e79b380d58142a363f0d
https://doi.org/10.1111/j.1476-5381.1993.tb13965.x
https://doi.org/10.1111/j.1476-5381.1993.tb13965.x
Publikováno v:
Physiotherapy Theory and Practice. 9:77-85
Preliminary results of the effects of physical exercise on recovery of function of peripheral nerves following a crush lesion are reported. The right sciatic nerves of 30 Wistar rats were crushed. They were then randomised over three groups: one grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4ccac6665c2411e730294fbd4166d66
https://doi.org/10.3109/09593989309052919
https://doi.org/10.3109/09593989309052919
Autor:
Suzanne van der Wijst, Victor M. Wiegant, Kim Brouns, Martijn J.H. Agterberg, Ben H.C. Westerink, R. Remie, Ralph Hamelink, Jan H. Brakkee, Edwin N. Spoelstra
Publikováno v:
Laboratory Animals, 44, 3, pp. 264-270
Laboratory Animals, 44(3), 264-270
Laboratory Animals, 44, 264-270
Laboratory Animals, 44(3), 264-270
Laboratory Animals, 44, 264-270
In animal models, devices such as indwelling catheters and intracranial cannulae are often fixed on the skull to allow sampling or injection in the freely moving animal. The most commonly used method to fixate these devices is by embedding them in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5b32ce524b98cf3951600907131e56
https://pubmed.ncbi.nlm.nih.gov/20573682
https://pubmed.ncbi.nlm.nih.gov/20573682