Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jan H. Lindeman"'
Autor:
Valur Emilsson, Valborg Gudmundsdottir, Alexander Gudjonsson, Thorarinn Jonmundsson, Brynjolfur G. Jonsson, Mohd A. Karim, Marjan Ilkov, James R. Staley, Elias F. Gudmundsson, Lenore J. Launer, Jan H. Lindeman, Nicholas M. Morton, Thor Aspelund, John R. Lamb, Lori L. Jennings, Vilmundur Gudnason
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Finding the genetic basis of protein expression can elucidate the genetic mechanisms of disease. Here, the authors link low-frequency and common DNA sequence variants to thousands of serum proteins, finding genetic overlap between circulating protein
Externí odkaz:
https://doaj.org/article/006df8274287477b88415fe0ace0b54a
Autor:
Laura E. Bruijn, BSc, Charid G. van Stroe Gómez, BSc, John A. Curci, MD, Jonathan Golledge, MChir, Jaap F. Hamming, MD, PhD, Greg T. Jones, PhD, Regent Lee, MD, PhD, Ljubica Matic, PhD, Connie van Rhijn, BSc, Patrick W. Vriens, MD, PhD, Dick Wågsäter, PhD, Baohui Xu, PhD, Dai Yamanouchi, MD, PhD, Jan H. Lindeman, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 2, Iss , Pp 260-273 (2021)
Objective: Two consensus histopathological classifications for thoracic aortic aneurysms (TAAs) and inflammatory aortic diseases have been issued to facilitate clinical decision-making and inter-study comparison. However, these consensus classificati
Externí odkaz:
https://doaj.org/article/7c4355b2d53d4b15864a35f6cc00cde6
Autor:
Jan H. Lindeman, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 314-315 (2022)
Externí odkaz:
https://doaj.org/article/63f8571430fa4822b06cd63c68c6a576
Autor:
Stephanie M. Tomee, Ruth M.A. Bulder, C. Arnoud Meijer, Ingrid van Berkum, Jan-Willem Hinnen, Jan W. Schoones, Jonathan Golledge, Esther Bastiaannet, Jon S. Matsumura, Jaap F. Hamming, Rebecka Hultgren, Jan H. Lindeman
Publikováno v:
European Journal of Vascular and Endovascular Surgery. 65:348-357
Previous studies imply a profound residual mortality risk following successful abdominal aorta aneurysm (AAA) repair. This excess mortality is generally attributed to increased cardiovascular risk. The aim of this study was (I) to quantify the excess
Autor:
Jan H Lindeman, Luuk Hulsbos, Antoon J van den Bogaerdt, Marlieke Geerts, Alain J van Gool, Jaap F Hamming, Rogier A van Dijk, Alexander F Schaapherder
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207943 (2018)
BACKGROUND AND AIMS:With the intention to gain support for the hypothesis that incident ischemic complications of atherosclerotic disease involve a stochastic aspect, we performed a histological, qualitative evaluation of the epidemiology of coronary
Externí odkaz:
https://doaj.org/article/8cd71e0fc09545cda289fab248f993b5
VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart
Autor:
Riikka Kivelä, Maija Bry, Marius R Robciuc, Markus Räsänen, Miia Taavitsainen, Johanna MU Silvola, Antti Saraste, Juha J Hulmi, Andrey Anisimov, Mikko I Mäyränpää, Jan H Lindeman, Lauri Eklund, Sanna Hellberg, Ruslan Hlushchuk, Zhen W Zhuang, Michael Simons, Valentin Djonov, Juhani Knuuti, Eero Mervaala, Kari Alitalo
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 3, Pp 307-321 (2014)
Abstract Angiogenic growth factors have recently been linked to tissue metabolism. We have used genetic gain‐ and loss‐of function models to elucidate the effects and mechanisms of action of vascular endothelial growth factor‐B (VEGF‐B) in th
Externí odkaz:
https://doaj.org/article/ebec774a221a4674a5d3e1c1b7a80b29
Autor:
Nimrat Grewal, Adriana C. Gittenberger-de Groot, Jan H. Lindeman, Arthur Klautz, Antoine Driessen, Robert J. M. Klautz, Robert E. Poelmann
Publikováno v:
ASVIDE. 9:153-153
Autor:
Kim E Kortekaas, C Arnoud Meijer, Jan Willem Hinnen, Ronald L Dalman, Baohui Xu, Jaap F Hamming, Jan H Lindeman
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e111952 (2014)
Independent of their blood pressure lowering effect, ACE inhibitors are thought to reduce vascular inflammation. The clinical relevance of this effect is unclear with the current knowledge. Abdominal aortic aneurysms (AAA) are characterized by a broa
Externí odkaz:
https://doaj.org/article/d44e917f46a049ebad71fca02d6626be
Autor:
Wen Liang, Aswin L Menke, Ann Driessen, Ger H Koek, Jan H Lindeman, Reinout Stoop, Louis M Havekes, Robert Kleemann, Anita M van den Hoek
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115922 (2014)
The recently developed histological scoring system for non-alcoholic fatty liver disease (NAFLD) by the NASH Clinical Research Network (NASH-CRN) has been widely used in clinical settings, but is increasingly employed in preclinical research as well.
Externí odkaz:
https://doaj.org/article/b646b4dc76244263af85254bb820701d
Autor:
Melissa, Zuiderwijk, Marlieke, Geerts, Connie J, van Rhijn, Antoon, van den Bogaerdt, Jaap F, Hamming, Rogier A, van Dijk, Jan H, Lindeman
Publikováno v:
The American journal of pathology. 188(7)
Atherosclerosis is a complex process with strong inflammatory component. We developed a straightforward sevenfold staining protocol for simultaneous assessment of dominant leukocyte classes, vascularization, and expression of the putative foam cell m