Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Jan H, von der Thüsen"'
Autor:
Sophie M. Ernst, Maaike M. Hofman, Tessa E. van der Horst, Marthe S. Paats, Frank W.J. Heijboer, Joachim G.J.V. Aerts, Daphne W. Dumoulin, Robin Cornelissen, Jan H. von der Thüsen, Peter de Bruijn, Esther Oomen-de Hoop, Ron H.J. Mathijssen, Stijn L.W. Koolen, Anne-Marie C. Dingemans
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105074- (2024)
Summary: Background: Sotorasib given after immunotherapy could put patients at increased risk of hepatotoxicity. Therefore, there is a need to gain insight into the potential correlation between anti-PD-(L)1 treatment, anti-PD-(L)1 concentrations, so
Externí odkaz:
https://doaj.org/article/a26effef666d4b159c43d8ae59e8c674
Autor:
Cathy van Horik, Marius J.P. Zuidweg, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Erwin Brosens, Alexander L. Vahrmeijer, Jan H. von der Thüsen, René M.H. Wijnen, Robbert J. Rottier, Willemieke S.F.J. Tummers, J. Marco Schnater
Publikováno v:
European Respiratory Review, Vol 32, Iss 170 (2023)
Currently there is a global lack of consensus about the best treatment for asymptomatic congenital pulmonary airway malformation (CPAM) patients. The somatic KRAS mutations commonly found in adult lung cancer combined with mucinous proliferations are
Externí odkaz:
https://doaj.org/article/e1949ce25ea74ee49bd6a9922350095f
Autor:
Denise van Uden, Thomas Koudstaal, Jennifer A. C. van Hulst, Thierry P. P. van den Bosch, Madelief Vink, Ingrid M. Bergen, Karishma A. Lila, Annemien E. van den Bosch, Paul Bresser, Mirjam Kool, Jan H. von der Thüsen, Rudi W. Hendriks, Karin A. Boomars
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionPrevious studies have shown an increase of T cells and chemokines in vascular lesions of patients with chronic thromboembolic pulmonary hypertension (CTEPH). However, detailed characterization of these T cells is still lacking, nor have t
Externí odkaz:
https://doaj.org/article/75ddaec85a8b4c6b8a6a50fcf91283fc
Autor:
Cleo Keppens, Elisabeth M. C. Dequeker, Etienne Rouleau, Nils ’t Hart, Lukas Bubendorf, Kelly Dufraing, Céline Garrec, Paul Guéguen, Aude Lamy, Antonio Marchetti, Patrick Pauwels, Ales Ryska, Véronique Tack, Luigi Tornillo, Kaat Van Casteren, Jan H. von der Thüsen, Karen Zwaenepoel, Birgit Lissenberg-Witte, Erik Thunnissen, Ed Schuuring
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Correct identification of the EGFR c.2369C>T p.(Thr790Met) variant is key to decide on a targeted therapeutic strategy for patients with acquired EGFR TKI resistance in non-small cell lung cancer. The aim of this study was to eval
Externí odkaz:
https://doaj.org/article/a6a32d9ed52f4d1a8db1c8899b5c04ee
Autor:
Stefan Roest, Jasper J. Brugts, Jeroen J.A. van Kampen, Jan H. von der Thüsen, Alina A. Constantinescu, Kadir Caliskan, Alexander Hirsch, Olivier C. Manintveld
Publikováno v:
International Journal of Infectious Diseases, Vol 107, Iss , Pp 34-36 (2021)
This report describes the first heart transplantation recipient with acute biventricular heart failure symptoms caused by a post-myocarditis state, late after a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. No other viral pa
Externí odkaz:
https://doaj.org/article/555a52055a384db48576b63c067ace80
Autor:
Liesbeth M. Hondelink, MD, Merel Jebbink, MD, Jan H. von der Thüsen, MD, PhD, Danielle Cohen, MD, PhD, Hendrikus J. Dubbink, PhD, Marthe S. Paats, MD, PhD, Anne-Marie C. Dingemans, MD, PhD, Adrianus J. de Langen, MD, PhD, Mirjam C. Boelens, PhD, Egbert F. Smit, MD, PhD, Pieter E. Postmus, MD, PhD, Tom van Wezel, PhD, Kim Monkhorst, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 12, Pp 100252- (2021)
Introduction: With the approval of first-line osimertinib treatment in stage IV EGFR-mutated NSCLC, detection of resistance mechanisms will become increasingly important—and complex. Clear guidelines for analyses of these resistance mechanisms are
Externí odkaz:
https://doaj.org/article/15653a46b49e44dca1398d582c62eabe
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 9, Pp 100215- (2021)
Externí odkaz:
https://doaj.org/article/43b105be02254cf4b18e4a1b8f56a023
Autor:
Daan P. Hurkmans, Jeroen G. H. P. Verhoeven, Kitty de Leur, Karin Boer, Arjen Joosse, Carla C. Baan, Jan H. von der Thüsen, Ron H. N. van Schaik, Ron H. J. Mathijssen, Astrid A. M. van der Veldt, Dennis A. Hesselink
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-7 (2019)
Abstract Background In solid organ transplant (SOT) recipients, transplant rejection during immune checkpoint inhibitor (ICI) treatment for cancer is a clinical problem. Donor-derived cell-free DNA (dd-cfDNA) can be detected in blood and is a sensiti
Externí odkaz:
https://doaj.org/article/3d6440bf678c4d57bbcc31c40868050e
Autor:
Sophie M. Ernst, Joanne M. Mankor, Job van Riet, Jan H. von der Thüsen, Hendrikus J. Dubbink, Joachim G.J.V. Aerts, Adrianus J. de Langen, Egbert F. Smit, Anne-Marie C. Dingemans, Kim Monkhorst
Publikováno v:
Journal of Thoracic Oncology, 18(4), 487-498. International Association for the Study of Lung Cancer
Introduction: Patient-reported smoking history is frequently used as a stratification factor in NSCLC-directed clinical research. Nevertheless, this classification does not fully reflect the mutational processes in a tumor. Next-generation sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cf9743a1479a3c4eba3c64ec721d08
http://www.scopus.com/inward/record.url?scp=85146015148&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85146015148&partnerID=8YFLogxK
Autor:
Robert A. Belderbos, MD, Alexander P.W.M. Maat, MD, Sara J. Baart, PhD, Eva V.E Madsen, MD, PhD, Ad J.J.C. Bogers, MD, PhD, Robin Cornelissen, MD, PhD, Joachim G.J.V. Aerts, MD, PhD, Edris A.F. Mahtab, MD, PhD, Jan H. von der Thüsen, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 4, Pp 100155- (2021)
Introduction: The role of surgery for early stage malignant pleural mesothelioma (MPM) remains controversial. Current expert opinion is only to treat patients surgically as part of multimodality therapy. It is still challenging to identify patients w
Externí odkaz:
https://doaj.org/article/4447ab56f7d74332a2ac3e2cf72ec1c8