Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jan H, Spaas"'
Autor:
Charlotte Beerts, Sarah Y. Broeckx, Eva Depuydt, Liesa Tack, Lore Van Hecke, Koen Chiers, Leen Van Brantegem, Gabriele Braun, Klaus Hellmann, Nathalie de Bouvre, Nathalie Van Bruaene, Tine De Ryck, Luc Duchateau, Bernadette Van Ryssen, Kathelijne Peremans, Jimmy H. Saunders, Geert Verhoeven, Glenn Pauwelyn, Jan H. Spaas
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-18 (2023)
Abstract Background As current therapies for canine osteoarthritis (OA) provide mainly symptomatic improvement and fail to address the complex pathology of the disease, mesenchymal stem cells (MSCs) offer a promising biological approach to address bo
Externí odkaz:
https://doaj.org/article/e56fcc19e4474e76ac94d69bf4a9985c
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
BackgroundMesenchymal stem cells provide a valuable treatment option in orthopedic injuries in horses.ObjectivesThe aim of this study was to evaluate the hematological, biochemical, immunological and immunomodulatory parameters following intralesiona
Externí odkaz:
https://doaj.org/article/408913271fac49d8b4454e961efdd9df
Autor:
Jonas Steenbrugge, Glenn Pauwelyn, Kristel Demeyere, Nausikaa Devriendt, Hilde de Rooster, Niek N. Sanders, Jan H. Spaas, Evelyne Meyer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Triple-negative breast cancer (TNBC) remains difficult to treat, especially due to ineffective immune responses. Current treatments mainly aim at a cytotoxic effect, whereas (stem) cell therapies are being investigated for their immune stimulatory ca
Externí odkaz:
https://doaj.org/article/150f70b8bbd7473a93977f298650025d
Autor:
Charlotte Beerts, Glenn Pauwelyn, Eva Depuydt, Yangfeng Xu, Jimmy H. Saunders, Kathelijne Peremans, Jan H. Spaas
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Osteoarthritis (OA) is a highly prevalent condition in dogs, causing a substantial reduction in quality of life and welfare of the animals. Current disease management focusses on pain relief but does not stop the progression of the disease. Therefore
Externí odkaz:
https://doaj.org/article/3978519a33404fde93223e481657c6d5
Autor:
Charlotte Beerts, Carlien Brondeel, Glenn Pauwelyn, Eva Depuydt, Liesa Tack, Luc Duchateau, Yangfeng Xu, Jimmy H. Saunders, Kathelijne Peremans, Jan H. Spaas
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Background Mesenchymal stem cell treatments in dogs have been investigated as a potential innovative alternative to current conventional therapies for a variety of conditions. So far, the precise mode of action of the MSCs has yet to be dete
Externí odkaz:
https://doaj.org/article/f6ef7d77df224e1a8cb4e5575acbef51
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/e08c6ed036ec4c5980e2e6aa94041fcf
Autor:
Eva Depuydt, Sarah Y. Broeckx, Koen Chiers, Marco Patruno, Laura Da Dalt, Luc Duchateau, Jimmy Saunders, Frederik Pille, Ann Martens, Lore Van Hecke, Jan H. Spaas
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2022)
The use of mesenchymal stem cells (MSCs) for the treatment of equine tendon disease is widely investigated because of their regenerative and immunomodulatory potential. However, questions have been raised concerning the immunogenic properties of allo
Externí odkaz:
https://doaj.org/article/555b82435a584f77b8d4af7d106fe9bc
Autor:
Carlien Brondeel, Glenn Pauwelyn, Evelien de Bakker, Jimmy Saunders, Yves Samoy, Jan H. Spaas
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Osteoarthritis (OA) is currently an incurable and progressive condition in dogs causing chronic joint pain and possibly increasing disability. Due to the poor healing capacity of cartilage lesions that occur with OA, development of effective therapeu
Externí odkaz:
https://doaj.org/article/b5e8e77bcaf74e5c96ccecd95ac0ea3b
Autor:
Eva Depuydt, Sarah Y. Broeckx, Lore Van Hecke, Koen Chiers, Leen Van Brantegem, Hans van Schie, Charlotte Beerts, Jan H. Spaas, Frederik Pille, Ann Martens
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Background: Tendon injuries are very common in horses and jeopardize the athletic performance, and due to the high risk of reinjury may lead to early retirement. The use of mesenchymal stem cells for the treatment of equine tendon disease is widely i
Externí odkaz:
https://doaj.org/article/2144e311e767474b833097467f706098
Autor:
Robert Daems, Lore Van Hecke, Ilona Schwarzkopf, Eva Depuydt, Sarah Y. Broeckx, Michael David, Charlotte Beerts, Peter Vandekerckhove, Jan H. Spaas
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Conventional treatments of osteoarthritis (OA) reduce pain and the inflammatory response but do not repair the damaged cartilage. Xenogeneic peripheral blood-derived equine chondrogenically induced mesenchymal stem cells (ciMSC) could thus provide an
Externí odkaz:
https://doaj.org/article/47ccbe5688364d6ca14a39532a9f6c26