Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jan Grosser"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009763 (2021)
The structural maintenance of chromosome (SMC) complex cohesin mediates sister chromatid cohesion established during replication, and damage-induced cohesion formed in response to DSBs post-replication. The translesion synthesis polymerase Polη is r
Externí odkaz:
https://doaj.org/article/a3d88a91aed548d38e29c534e4bbc1f5
Autor:
Donald P. Cameron, Jan Grosser, Swetlana Ladigan, Vladislav Kuzin, Evanthia Iliopoulou, Anika Wiegard, Hajar Benredjem, Sven T. Liffers, Smiths Lueong, Phyllis F. Cheung, Deepak Vangala, Michael Pohl, Richard Viebahn, Christian Teschendorf, Heiner Wolters, Selami Usta, Keyi Geng, Claudia Kutter, Marie Arsenian-Henriksson, Jens T. Siveke, Andrea Tannapfel, Wolff Schmiegel, Stephan A. Hahn, Laura Baranello
Pancreatic carcinoma is one of the most lethal cancers and the absence of efficient therapeutic strategies results in poor prognosis. Transcriptional dysregulation due to alterations in KRAS and MYC impacts initiation, development, and survival of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf901fd90d88257c9f0696f228c9e63e
https://doi.org/10.1101/2023.02.10.527824
https://doi.org/10.1101/2023.02.10.527824
Autor:
Alice Meroni, Jan Grosser, Sumedha Agashe, Natasha Ramakrishnan, Jessica Jackson, Priyanka Verma, Laura Baranello, Alessandro Vindigni
Publikováno v:
Science Advances. 8
DNA topoisomerase 1 (TOP11) inhibitors are mainstays of anticancer therapy. These drugs trap TOP1 on DNA, stabilizing the TOP1-cleavage complex (TOP1-cc). The accumulation of TOP1-ccs perturbs DNA replication fork progression, leading to DNA breaks a
Autor:
Anjana Shenoy, Arthur Mathes, Gergana Dobreva, Marius Bruer, Johanna Schott, Tamar Geiger, Georg Stoecklin, Sonja Reitter, Jan Grosser, Doris Lindner
Publikováno v:
Nature Methods. 18:1068-1074
In general, mRNAs are assumed to be loaded with ribosomes instantly upon entry into the cytoplasm. To measure ribosome density (RD) on nascent mRNA, we developed nascent Ribo-Seq by combining Ribo-Seq with progressive 4-thiouridine labeling. In mouse
Autor:
Johanna Schott, Sonja Reitter, Doris Lindner, Jan Grosser, Marius Bruer, Anjana Shenoy, Tamar Geiger, Arthur Mathes, Gergana Dobreva, Georg Stoecklin
Publikováno v:
Nature Methods. 20:316-316
Autor:
Ulrich Reidt, Jan Grosser, S. N. Kharin, Andreas Helwig, Joachim Lenic, Gerhard Dr. Müller, Andrei Kornienko, Viktor Fetter, Thomas Hummel, N. M. Novikova
Publikováno v:
Gravitational and Space Research. 8:1-17
In this work, we report on the construction, training and functional assessment of an electronic nose (called ‘E-Nose’) that is capable of monitoring the microbial contamination onboard space ships under microgravity conditions. To this end, a co
The structural maintenance of chromosome (SMC) complex cohesin mediates sister chromatid cohesion established during replication, and damage-induced cohesion formed in response to DSBs post-replication. The translesion synthesis polymerase Polη is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96f57c7911d3b935d3efc0ca4b86956a
https://doi.org/10.1101/2020.12.20.423707
https://doi.org/10.1101/2020.12.20.423707
Autor:
Johanna, Schott, Sonja, Reitter, Doris, Lindner, Jan, Grosser, Marius, Bruer, Anjana, Shenoy, Tamar, Geiger, Arthur, Mathes, Gergana, Dobreva, Georg, Stoecklin
Publikováno v:
Nature methods. 18(9)
In general, mRNAs are assumed to be loaded with ribosomes instantly upon entry into the cytoplasm. To measure ribosome density (RD) on nascent mRNA, we developed nascent Ribo-Seq by combining Ribo-Seq with progressive 4-thiouridine labeling. In mouse
Autor:
Roberto Ballarino, Toyoaki Natsume, Laura Baranello, Rashid Mehmood, Radosław Grochowski, Anika Wiegard, Jan Grosser, Michele Ceribelli, Donald P. Cameron, Anna H. Bizard, Fedor Kouzine, Nicola Crosetto, Vladislav Kuzin, Arne Lindqvist, Ivana Karabogdan, Francesco Valant
Publikováno v:
Wiegard, A, Kuzin, V, Cameron, D P, Grosser, J, Ceribelli, M, Mehmood, R, Ballarino, R, Valant, F, Grochowski, R, Karabogdan, I, Crosetto, N, Lindqvist, A, Bizard, A H, Kouzine, F, Natsume, T & Baranello, L 2021, ' Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1 ', Molecular Cell, vol. 81, no. 24, pp. 5007-5024.e9 . https://doi.org/10.1016/j.molcel.2021.10.015
As cells enter mitosis, chromatin compacts to facilitate chromosome segregation yet remains transcribed. Transcription supercoils DNA to levels that can impede further progression of RNA polymerase II (RNAPII) unless it is removed by DNA topoisomeras
Autor:
Marcus A. Koch, Jan Grosser
Publikováno v:
Botanical Journal of the Linnean Society. 184:224-237