Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jan Greulich"'
Autor:
Dennis Merk, Jan Greulich, Annika Vierkant, Fiona Cox, Olaf Eckermann, Florian von Ameln, Nadine Dyballa-Rukes, Joachim Altschmied, Niloofar Ale-Agha, Philipp Jakobs, Judith Haendeler
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1244 (2023)
The maintenance of Thioredoxin-1 (Trx-1) levels, and thus of cellular redox homeostasis, is vital for endothelial cells (ECs) to prevent senescence induction. One hallmark of EC functionality, their migratory capacity, which depends on intact mitocho
Externí odkaz:
https://doaj.org/article/b92924c50b2547cd84703aa0bc08e0b4
Autor:
Dennis Merk, Johannes Ptok, Philipp Jakobs, Florian von Ameln, Jan Greulich, Pia Kluge, Kathrin Semperowitsch, Olaf Eckermann, Heiner Schaal, Niloofar Ale-Agha, Joachim Altschmied, Judith Haendeler
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1427 (2021)
Sepsis is an exaggerated immune response upon infection with lipopolysaccharide (LPS) as the main causative agent. LPS-induced activation and apoptosis of endothelial cells (EC) can lead to organ dysfunction and finally organ failure. We previously d
Externí odkaz:
https://doaj.org/article/ad537b1b030145a1a01499ff88b43551
Autor:
Kirsten Jander, Jan Greulich, Stefanie Gonnissen, Niloofar Ale-Agha, Christine Goy, Philipp Jakobs, Sabrina Farrokh, Corina Marziano, Swapnil K. Sonkusare, Judith Haendeler, Joachim Altschmied
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 428 (2021)
We previously demonstrated that the transcription factor Grainyhead-like 3 (GRHL3) has essential functions in endothelial cells by inhibiting apoptosis and promoting migration as well as activation of endothelial nitric oxide synthase (eNOS). We now
Externí odkaz:
https://doaj.org/article/cacda6784fe64f48b1f84bf0b3dd054e
Autor:
Haendeler, Dennis Merk, Jan Greulich, Annika Vierkant, Fiona Cox, Olaf Eckermann, Florian von Ameln, Nadine Dyballa-Rukes, Joachim Altschmied, Niloofar Ale-Agha, Philipp Jakobs, Judith
Publikováno v:
Antioxidants; Volume 12; Issue 6; Pages: 1244
The maintenance of Thioredoxin-1 (Trx-1) levels, and thus of cellular redox homeostasis, is vital for endothelial cells (ECs) to prevent senescence induction. One hallmark of EC functionality, their migratory capacity, which depends on intact mitocho
Autor:
Scott Yeudall, Clint M. Upchurch, Philip V. Seegren, Caitlin M. Pavelec, Jan Greulich, Michael C. Lemke, Thurl E. Harris, Bimal N. Desai, Kyle L. Hoehn, Norbert Leitinger
Publikováno v:
Science Advances. 8
Acetyl-CoA carboxylase (ACC) regulates lipid synthesis; however, its role in inflammatory regulation in macrophages remains unclear. We generated mice that are deficient in both ACC isoforms in myeloid cells. ACC deficiency altered the lipidomic, tra
Autor:
Clint M. Upchurch, Scott Yeudall, Caitlin M. Pavelec, Dennis Merk, Jan Greulich, Mohan Manjegowda, Shyam S. Raghavan, Irina M. Bochkis, Michael M. Scott, Edward Perez-Reyes, Norbert Leitinger
Publikováno v:
Science advances. 8(28)
Oxidized phosphatidylcholines (OxPCs) are implicated in chronic tissue damage. Hyperlipidemic LDL-R-–deficient mice transgenic for an OxPC-recognizing IgM fragment (scFv-E06) are protected against nonalcoholic fatty liver disease (NAFLD). To examin
Autor:
Jan Greulich, Annika Vierkant, Ale-Agha Niloofar, Jakobs Philipp, Fiona Cox, Dennis Merk, Swapnil Sonkusare, Judith Haendeler, Joachim Altschmied
Publikováno v:
Journal of Biological Chemistry. 299:103990
Autor:
Dennis Merk, Ptok Johannes, Jakobs Philipp, Jan Greulich, Florian Von Ameln, Schaal Heiner, Ale-Agha Niloofar, Joachim Altschmied, Judith Haendeler
Publikováno v:
Journal of Biological Chemistry. 299:104282
Autor:
Clint Upchurch, Scott Yeudall, Caitlin Pavelec, Dennis Merk, Jan Greulich, Mohan Manjegowda, Shyam Raghavan, Irina Bochkis, Michael Scott, Edward Perez-Reyes, Norbert Leitinger
Publikováno v:
Free Radical Biology and Medicine. 192:93
Autor:
Stefanie Gonnissen, Kirsten Jander, Niloofar Ale-Agha, Swapnil K. Sonkusare, Christine Goy, Judith Haendeler, Joachim Altschmied, Corina Marziano, Jan Greulich, Sabrina Farrokh, Philipp Jakobs
Publikováno v:
Antioxidants
Volume 10
Issue 3
Antioxidants, Vol 10, Iss 428, p 428 (2021)
Volume 10
Issue 3
Antioxidants, Vol 10, Iss 428, p 428 (2021)
We previously demonstrated that the transcription factor Grainyhead-like 3 (GRHL3) has essential functions in endothelial cells by inhibiting apoptosis and promoting migration as well as activation of endothelial nitric oxide synthase (eNOS). We now