Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jan F. Richter"'
Autor:
Deborah Delbue, Lydia Lebenheim, Danielle Cardoso-Silva, Violaine Dony, Susanne M. Krug, Jan F. Richter, Subhakankha Manna, Melba Muñoz, Kerstin Wolk, Claudia Heldt, Markus M. Heimesaat, Robert Sabat, Britta Siegmund, Michael Schumann
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Interleukin-22 (IL-22) impacts the integrity of intestinal epithelia and has been associated with the development of colitis-associated cancer and inflammatory bowel diseases (IBD). Previous data suggest that IL-22 protects the mucosal ba
Externí odkaz:
https://doaj.org/article/113c05147356492e9a76707d9906f783
Publikováno v:
Proceedings XXXII Reunión Internacional de Producción de Carne y Leche en Climas Cálidos. 30:95-101
Autor:
Silke S Zakrzewski, Jan F Richter, Susanne M Krug, Britta Jebautzke, In-Fah M Lee, Juliane Rieger, Monika Sachtleben, Angelika Bondzio, Jörg D Schulzke, Michael Fromm, Dorothee Günzel
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79643 (2013)
Cell lines matching the source epithelium are indispensable for investigating porcine intestinal transport and barrier properties on a subcellular or molecular level and furthermore help to reduce animal usage. The porcine jejunal cell line IPEC-J2 i
Externí odkaz:
https://doaj.org/article/16ba4617e0394c8081afad0bee7a5681
Autor:
Anja Fromm, Michael Fromm, In-Fah M. Lee, Jörg-Dieter Schulzke, Petra Dames, Turner, Jan F. Richter, Susanne M. Krug, Christian Bojarski
Publikováno v:
Mucosal immunology
In the two inflammatory bowel diseases, ulcerative colitis (UC) and Crohn’s disease (CD), altered expression of tight junction (TJ) proteins leads to an impaired epithelial barrier including increased uptake of luminal antigens supporting the infla
Autor:
Jan F. Richter, Juliane Reiche, Jerrold R. Turner, Michael Schumann, Markus Hildner, Ralf Schmauder
Publikováno v:
Tissue Barriers
Occludin, a tight junction protein, has been reported to regulate barrier function - particularly the leak pathway for larger solutes - in epithelia. Therefore, we aimed to precisely define its role in macromolecule passage at single cell-cell juncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bedd4b496ec1b463221c7706312b9bf
https://europepmc.org/articles/PMC6619991/
https://europepmc.org/articles/PMC6619991/
Publikováno v:
Journal of Controlled Release. 229:70-79
Understanding the dynamics of intestinal barrier function is key to elucidating oral delivery routes of therapeutics as well as to understanding various diseases that involve the mucosal immune system. Passage of macromolecules across barrier-forming
Publikováno v:
Current protocols in cell biology. 78(1)
To date, the permeability of epithelia to larger solutes (greater than ∼4 A in diameter) has been analyzed by flux measurements using various tracers that cannot spatially resolve the permeation sites. This unit describes a method for localizing su
Autor:
Reimar Krieg, Stefan Schramm, Dieter Weiss, Luiz Francisco Monteiro Leite Ciscato, Isabelle Navizet, Daniel Roca-Sanjuán, Rainer Beckert, Pascal Oeseau, Jan F. Richter
Publikováno v:
ARKIVOC-Online Journal of Organic Chemistry
ARKIVOC-Online Journal of Organic Chemistry, Arkat USA Inc, 2015, 2015 (5), pp.44-59. ⟨10.3998/ark.5550190.p009.044⟩
ARKIVOC, Vol 2015, Iss 5, Pp 44-59 (2015)
ARKIVOC-Online Journal of Organic Chemistry, Arkat USA Inc, 2015, 2015 (5), pp.44-59. ⟨10.3998/ark.5550190.p009.044⟩
ARKIVOC, Vol 2015, Iss 5, Pp 44-59 (2015)
International audience; The optimized one-pot synthesis of 16 new 2-coumaranones containing a carbamate side-chain is described. Furthermore, the quantum yields for the base-activated chemiluminescence in the presence of oxygen was determined for all
Autor:
Dorothee Günzel, Karsten Nöckler, Friederike Ebner, Nina A. Hering, Jan F. Richter, Lothar H. Wieler, Anja A. Kühl, Jörg-Dieter Schulzke, Ahmed Keles, Pawel Janczyk, Susanne Hartmann, Rose A. K. Whelan, Sebastian Rausch
Publikováno v:
Molecular Therapy. 22(10):1730-1740
New treatment strategies for inflammatory bowel disease are needed and parasitic nematode infections or application of helminth components improve clinical and experimental gut inflammation. We genetically modified the probiotic bacterium Escherichia
Publikováno v:
Zeitschrift für Gastroenterologie. 54