Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jan E. Romano"'
Publikováno v:
Bioconjugate Chemistry. 15:1068-1075
Previously, we showed that labeled bitistatin analogues possessed excellent characteristics for imaging both deep-vein thrombosis and pulmonary embolism. We hypothesized that the N-terminal amino acid sequence of bitistatin, which is different from o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38ed93cb8956886ea79ace79028b163
https://doi.org/10.1021/bc049954v
https://doi.org/10.1021/bc049954v
Autor:
Scott H. Faro, Linda C. Knight, Barbara Krynska, Jan E. Romano, Jennifer Gordon, Feroze B. Mohamed
Publikováno v:
Journal of molecular biomarkersdiagnosis. 1(1)
A targeted nanoconjugate is being developed for non-invasive detection of gene expression in cells expressing the JC virus oncoprotein, T-antigen, which has been associated with medulloblastoma and other cancers. JC virus T-antigen localizes predomin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5235a811fac5fde204d3a2ac2420366c
https://pubmed.ncbi.nlm.nih.gov/23487404
https://pubmed.ncbi.nlm.nih.gov/23487404
Disintegrins, which contain an Arg-Gly-Asp sequence in their binding domains are antagonists of integrins such as αvβ3. The purpose of this study was to compare a range of disintegrins with different integrin selectivities for their binding behavio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f13aea2443db497a23045192fb875b1
https://europepmc.org/articles/PMC1986642/
https://europepmc.org/articles/PMC1986642/
Autor:
Alexis Agelan, Lewis T. Bright, Alan H. Maurer, Jan E. Romano, Steven Kantor, Linda C. Knight
Publikováno v:
Nuclear medicine and biology. 34(7)
Introduction 99m Tc recombinant bitistatin (rBitistatin) is a radioligand for α IIb β 3 (glycoproteins IIb/IIIa) receptor on platelets and is being developed as a diagnostic radiopharmaceutical for in vivo imaging of acute thrombi and emboli. Prior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a68227e708a55dabf473ce4ce3f2bbb
https://pubmed.ncbi.nlm.nih.gov/17921036
https://pubmed.ncbi.nlm.nih.gov/17921036
Autor:
Linda C. Knight, Jan E. Romano
Publikováno v:
Protein expression and purification. 39(2)
Bitistatin is a single-chain disintegrin which contains 83 amino acids and is internally crosslinked with seven disulfide bonds. This platelet aggregation inhibitor, which binds with high affinity to the alphaIIbbeta3 integrin, has potential use as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56c3b70071af17f7ed5dd4d97a3823d
https://pubmed.ncbi.nlm.nih.gov/15642483
https://pubmed.ncbi.nlm.nih.gov/15642483
Autor:
Jan E. Romano, Robert D. Campo
Publikováno v:
Calcified Tissue International. 39:175-184
The purposes of these experiments were to study the biosynthetic and postbiosynthetic relationships between proteoglycans in noncalcified growth cartilage and calcified cartilage in metaphysis from the costochondral junctions of immature rabbits. Bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e8622db9d008e3a6016a1ef02a5c9d
https://doi.org/10.1007/bf02555115
https://doi.org/10.1007/bf02555115