Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jan E. Lerbinger"'
Autor:
Heejong Sung, Jan E. Lerbinger, J. Alexander Bodkin, Deborah L. Levy, Charity J. Morgan, Michael J. Coleman, Fred Johnson
Publikováno v:
Schizophrenia Bulletin. 45:S341-S342
BACKGROUND: Although thought disorder (TD) is a fundamental component of serious mental illness (SMI), qualitatively and quantitatively distinct TD phenotypes are associated with schizophrenia and bipolar disorder, both in patients and in their clini
Autor:
Lenore Boling, J. Alexander Bodkin, Steven Matthysse, Curtis K. Deutsch, Deborah L. Levy, Fred Johnson, Michael J. Coleman, Jan E. Lerbinger, Philip S. Holzman, Selya F. R. Price
Publikováno v:
Schizophrenia Bulletin. 41:1309-1316
Several laboratories, including ours, have reported an overrepresentation of craniofacial (CF) anomalies in schizophrenia (SZ). How might this dysmorphology arise in a brain-based disorder? Because the brain and face derive from shared embryologic pr
Autor:
Jan E. Lerbinger, Philip S. Holzman, Lenore Boling, Fred Johnson, Michael J. Coleman, J. Alexander Bodkin, Ayse Ulgen, Charity J. Morgan, Deborah L. Levy, Jonathan O. Cole
Publikováno v:
Schizophrenia bulletin. 43(3)
Thought disorder (TD) has long been associated with schizophrenia (SZ) and is now widely recognized as a symptom of mania and other psychotic disorders as well. Previous studies have suggested that the TD found in the clinically unaffected relatives
Autor:
Verena Krause, Michael J. Coleman, Fred Johnson, Jan E. Lerbinger, Lenore Boling, Nancy R. Mendell, Jonathan O. Cole, Anne Gibbs, Deborah L. Levy, Olga Krastoshevsky, J. Alexander Bodkin, Zhuying Huang
Publikováno v:
Schizophrenia Research. 116:133-142
The delineation of schizophrenia-related symptomatology is critical to informative clinical phenotyping in linkage studies. A minority of first-degree relatives of schizophrenia and schizoaffective probands (RelSZSA) qualifies for a clinical diagnosi
Autor:
Philip J. Langlais, Jonathan O. Cole, Jan E. Lerbinger, Alan F. Schatzberg, Anthony J. Rothschild, Marijean M. Miller
Publikováno v:
Psychiatry Research. 20:143-153
Unconjugated plasma catecholamines and cortisol were measured before and after a 1 mg dose of dexamethasone in 22 medication-free depressed patients and 6 healthy, medication-free control subjects. Plasma dopamine (DA) levels in the psychotically dep
Autor:
Anthony J. Rothschild, Alan F. Schatzberg, Marijean M. Miller, Melinda S. Saloman, Jonathan O. Cole, Philip J. Langlais, Edward D. Bird, Jan E. Lerbinger
Publikováno v:
Life Sciences. 36:2491-2501
Twenty male Sprague-Dawley rats were injected intraperitoneally with either 20 micrograms of dexamethasone or an equivalent volume of saline. The rats were then sacrificed at either one or four hours after the injections and their brains analyzed for
Publikováno v:
Biological Psychiatry. 21:1239-1246
Results of the Dexamethasone Suppression Test (DST), performed on 65 patients with major unipolar depression, were classified both by suppression versus nonsuppression and by three ranges of postdexamethasone cortisol levels. Subgroups of patients we
Autor:
Joseph J. Schildkraut, Jan E. Lerbinger, Anthony J. Rothschild, Jonathan O. Cole, Alan F. Schatzberg, Paul J. Orsulak, Melinda Salomon, Patricia P. Kizuka
Publikováno v:
American Journal of Psychiatry. 140:1231-1233
Platelet monoamine oxidase (MAO) activity and postdexamethasone cortisol levels were determined in 26 depressed patients. The incidence of cortisol nonsuppression and the mean postdexamethasone cortisol levels were significantly higher in patients wi
Autor:
Jan E. Lerbinger, Joseph J. Schildkraut, Anthony J. Rothschild, Philip J. Langlais, Jonathan O. Cole, Alan R. Schatzberg
Publikováno v:
Psychiatry research. 20(2)
Preliminary data are presented on levels of plasma cortisol, dopamine (DA), epinephrine (RPI), and norepinephrine (NE) before and after dexamethasone in 22 depressed patients (of whom 4 were psychotic). Platelet monoamine oxidase (MAO) activity, dete
Autor:
Joseph J. Schildkraut, Patricia P. Kizuka, Benjamin Gerson, Melinda Salomon, John J. Mooney, Jan E. Lerbinger, Jonathan O. Cole, Kathleen M. Pappalardo, Alan F. Schatzberg
Publikováno v:
Biological psychiatry. 23(6)
The present study examined the relationship between 24-hr urinary catecholamine (norepinephrine and epinephrine) output and measures of platelet adenylate cyclase (AC) activity in depressed patients (n = 17) and control subjects (n = 10). In both gro