Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Jan E. Dyr"'
Publikováno v:
Metabolites, Vol 11, Iss 5, p 307 (2021)
Fibrinogen is an abundant blood plasma protein that, inter alia, participates in blood coagulation. It polymerizes to form a fibrin clot that is among the major components of the thrombus. Fibrinogen reactions with various reactive metabolites may in
Externí odkaz:
https://doaj.org/article/85a5c0b4f9084fce85c8fa524700afa1
Publikováno v:
Turkish Journal of Hematology, Vol 34, Iss 1, Pp 111-113 (2017)
Externí odkaz:
https://doaj.org/article/992766d419f34bd69e9a280ce2b12e41
Autor:
Martin Hajsl, Alzbeta Hlavackova, Karolina Broulikova, Martin Sramek, Martin Maly, Jan E. Dyr, Jiri Suttnar
Publikováno v:
Metabolites, Vol 10, Iss 5, p 208 (2020)
Atherosclerosis is a leading cause of major vascular events, myocardial infarction, and ischemic stroke. Tryptophan (TRP) catabolism was recognized as an important player in inflammation and immune response having together with oxidative stress (OS)
Externí odkaz:
https://doaj.org/article/b1bb9d730fd34a5583d28faa8b43987c
Autor:
Jana Štikarová, Roman Kotlín, Tomáš Riedel, Jiří Suttnar, Kristýna Pimková, Leona Chrastinová, Jan E. Dyr
Publikováno v:
The Scientific World Journal, Vol 2013 (2013)
Fibrinogen is one of the plasma proteins most susceptible to oxidative modification. It has been suggested that modification of fibrinogen may cause thrombotic/bleeding complications associated with many pathophysiological states of organism. We expo
Externí odkaz:
https://doaj.org/article/9b984c4d9edf402c8538bbe4dd476d99
Autor:
Pavel Majek, Zofie Sovova, Klara Pecankova, Jaroslav Cermak, Zdenka Gasova, Pavla Pecherkova, Vera Ignjatovic, Jan E. Dyr
Publikováno v:
Cancer biomarkers : section A of Disease markers. 34(3)
BACKGROUND: Leucine-rich alpha-2-glycoprotein (LRG) has been repeatedly proposed as a potential plasma biomarker for myelodysplastic syndrome (MDS). OBJECTIVE: The goal of our work was to establish the total LRG plasma level and LRG posttranslational
Autor:
Martin Hajšl, Ondrej Kucerka, Jan E. Dyr, Petr Tousek, John W. Weisel, Jirina Kaufmanova, Martin Maly, Jiri Suttnar, Jana Štikarová, Roman Kotlín, Tomáš Riedel
Publikováno v:
Thrombosis and haemostasis. 122(3)
We describe the internal structure, spatial organization and dynamic formation of coronary artery thrombi from ST-segment elevation myocardial infarction patients. Scanning electron microscopy (SEM) revealed significant differences among four groups
Publikováno v:
Metabolites
Volume 11
Issue 5
Metabolites, Vol 11, Iss 307, p 307 (2021)
Volume 11
Issue 5
Metabolites, Vol 11, Iss 307, p 307 (2021)
Fibrinogen is an abundant blood plasma protein that, inter alia, participates in blood coagulation. It polymerizes to form a fibrin clot that is among the major components of the thrombus. Fibrinogen reactions with various reactive metabolites may in
Autor:
Milan Raska, Stuart Macaulay, Andrea Vítečková Wünschová, František Hubatka, Pavel Kulich, Eva Vohlídalová, Petr Malý, Robert Mikulik, Pavlína Turánek Knotigová, Jan Kotouček, Josef Mašek, Jan E. Dyr, Hana Štikarová, Eliška Bartheldyová, Hana Petroková, Jaroslav Turánek, Milan Kuchar
Publikováno v:
Stroke. 51
Introduction: Direct clot targeting represents attractive concept for clot imaging as well as targeted delivery of drugs, e.g. thrombolytics. Small protein binders attached to nanoliposomes may target thrombi and deliver drugs although selective affi
Autor:
Jiří Suttnar, Žofie Sovová, Pavel Májek, Martin Malý, Jan E. Dyr, Pavel Šácha, Jana Štikarová, Jiřina Kaufmanová
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227543 (2020)
PLoS ONE
PLoS ONE
Oxidative stress in humans is related to various pathophysiological processes, which can manifest in numerous diseases including cancer, cardiovascular diseases, and Alzheimer’s disease. On the atomistic level, oxidative stress causes posttranslati
Autor:
Monika Belickova, Anna Jonasova, Zdenek Krejcik, Jaroslav Cermak, Jan E. Dyr, Andrea Hrustincova, Michaela Dostalova Merkerova, Hana Votavova
Publikováno v:
Cancer Biomarkers. 22:101-110
Background Azacitidine (AZA) is a nucleoside analog used for treatment of myelodysplasia and the prediction of AZA responsiveness is important for the therapy management. Methods Using microarrays and reverse-transcription quantitative-PCR, we analyz