Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jan Drimal"'
Autor:
Ludmila Okruhlicova, Jan Slezak, Jan Drimal, Vladimir Knezl, Lamosová D, Ján Styk, Narcis Tribulova
Publikováno v:
Experimental Physiology. 89:629-636
Hypokalaemia increases the risk for life-threatening arrhythmias; however, data about interaction with thyroid status are lacking. The aim of this study was to investigate vulnerability of l-thyroxine (T4)-treated adult and old rats to low K+-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c601d519aafeed3cf5ea497795b7c867
https://doi.org/10.1113/expphysiol.2004.027607
https://doi.org/10.1113/expphysiol.2004.027607
Publikováno v:
Journal of Medicinal Chemistry. 47:2750-2760
Both quantitative and qualitative chemical function based pharmacophore models of endothelin-A (ET(A)) selective receptor antagonists were generated by using the two algorithms HypoGen and HipHop, respectively, which are implemented in the Catalyst m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28a0907c92493073cc8ad2d5a056539
https://doi.org/10.1021/jm031041j
https://doi.org/10.1021/jm031041j
Publikováno v:
Life Sciences. 65:1939-1941
Binding of endothelin (ET) peptides to their respective receptors with resulting proliferation of vascular smooth muscle has been implicated in the pathogenesis of arterial hypertension and atherosclerosis. Recently it was hypothesized that endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf171e2482f8e7e1aa1552560ffb4531
https://doi.org/10.1016/s0024-3205(99)00452-x
https://doi.org/10.1016/s0024-3205(99)00452-x
Autor:
Jan, Drimal, Vladimir, Knezl, Jana, Navarova, Jana, Nedelcevova, Ema, Paulovicova, Ruzena, Sotnikova, Vladimir, Snirc, Daniel, Drimal
Publikováno v:
Endocrine regulations. 42(4)
It is not yet clear how oxidative stress, free radicals, inflammatory cytokines and chemoattractants produced in the heart induce chronic heart failure. The myocardial damage caused by chronic diabetes results either from the persistence of inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e909a7fc533692751b4e87f81eeeb7e7
https://pubmed.ncbi.nlm.nih.gov/18999900
https://pubmed.ncbi.nlm.nih.gov/18999900
Autor:
Narcis, Tribulova, Vladimir, Knezl, Ludmila, Okruhlicova, Jan, Drimal, Dalma, Lamosova, Jan, Slezak, Jan, Styk
Publikováno v:
Experimental physiology. 89(5)
Hypokalaemia increases the risk for life-threatening arrhythmias; however, data about interaction with thyroid status are lacking. The aim of this study was to investigate vulnerability of l-thyroxine (T(4))-treated adult and old rats to low K(+)-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d81597462fb089d2a9cc8f872c3aed1
https://pubmed.ncbi.nlm.nih.gov/15258117
https://pubmed.ncbi.nlm.nih.gov/15258117
Autor:
Jan Drimal, Daniel Drimal
Publikováno v:
European journal of pharmacology. 396(1)
The characteristics of specific binding of human [ 125 I]Tyr 13 -endothelin-(1–21), [ 125 I]-Tyr 13 -Suc-[Glu 9 ,Ala 11,15 ]-endothelin-(8–21), ([ 125 I]IRL-1620) and endothelin ET A receptor antagonist [ 125 I]Tyr 3 -( N -[(hexahydro-1 H -azepin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5060e54220018547ad47b06593508e9
https://pubmed.ncbi.nlm.nih.gov/10822048
https://pubmed.ncbi.nlm.nih.gov/10822048
Autor:
Jan Drimal
Publikováno v:
Cellular signalling. 3(3)
The receptor sites for 1,4-dihydropyridine (DHP) calcium channels ligands were identified and pharmacologically characterized in partially purified canine coronary artery smooth muscle (CSM) membranes (purification factor 1,4-DHPs 2.8 and 2.2 respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4ed19ee1e06d24a65e3cca01c8733a
https://pubmed.ncbi.nlm.nih.gov/1716451
https://pubmed.ncbi.nlm.nih.gov/1716451
Autor:
Marcela Fialova, Katarina Dlugosova, Vladimir Knezl, Ludmila Okruhlicova, Jan Drimal, Narcis Tribulova
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b64f8bbf98cdb5b64947df49c650ef21
https://doi.org/10.1016/j.yjmcc.2007.03.034
https://doi.org/10.1016/j.yjmcc.2007.03.034
Autor:
Domingo M. Aviado, Jan Drimal
Publikováno v:
The Journal of Clinical Pharmacology. 15:116-128
The exposure of the upper respiratory tract to aerosol propellants produces apnea, bradycardia, and biphasic fall and rise in aortic blood pressure in anesthetized dogs. This response represents the irritation of sensory receptors in the nasal and na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be733b558736fd7677bb84c71099aaa8
https://doi.org/10.1002/j.1552-4604.1975.tb01438.x
https://doi.org/10.1002/j.1552-4604.1975.tb01438.x
Publikováno v:
Toxicology and Applied Pharmacology. 21:464-481
The prototype pyridoquinoline compound used in this investigation was azacrin (2-methoxy-7-chloro-10[4,diethylamino-1-methylbutylamino]-pyrido[3,2-b]-quinoline). In the anesthetized dog, azacrin, quinacrine and primaquine had a similar cardiopulmonar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d42abf9652629d87b5ac26adb251b88
https://doi.org/10.1016/0041-008x(72)90004-x
https://doi.org/10.1016/0041-008x(72)90004-x