Guidance Document on Scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals

Autor: EFSA Scientific Committee, Simon John More, Vasileios Bampidis, Diane Benford, Claude Bragard, Antonio Hernandez‐Jerez, Susanne Hougaard Bennekou, Thorhallur Ingi Halldorsson, Konstantinos Panagiotis Koutsoumanis, Claude Lambré, Kyriaki Machera, Hanspeter Naegeli, Søren Saxmose Nielsen, Josef Rudolf Schlatter, Dieter Schrenk, Vittorio Silano, Dominique Turck, Maged Younes, Emilio Benfenati, Amélie Crépet, Jan Dirk Te Biesebeek, Emanuela Testai, Bruno Dujardin, Jean Lou CM Dorne, Christer Hogstrand

Publikováno v: EFSA Journal, Vol 19, Iss 12, Pp n/a-n/a (2021)

Abstract This guidance document provides harmonised and flexible methodologies to apply scientific criteria and prioritisation methods for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals.

Externí odkaz: https://doaj.org/article/bfe9777a9d854564a8429b23751f3f35

Cyclic-AMP mediated drugs: differential or global reduction of eicosanoid synthesis in the isolated rat lung?

Autor: Mark J. Post, Jan Dirk te Biesebeek, Johan Wemer, Hans H. van Rooij, Freek J. Zijlstra, Arijan J. Porsius

Publikováno v: Mediators of Inflammation, Vol 1, Iss 4, Pp 255-261 (1992)

In this study the question was addressed whether cAMP mediated drugs induce a differential reduction of branches of the arachidonic acid metabolism rather than a global reduction of eicosanoid synthesis. The isolated lungs of actively sensitized rats

Externí odkaz: https://doaj.org/article/1f377c7cf6c545f08e75d8197e8dd1f6

Human risk assessment of multiple chemicals using component‐based approaches: A horizontal perspective

Autor: Christer Hogstrand, Amélie Crépet, Kyriaki Machera, Jean Lou Cm Dorne, Jan Dirk te Biesebeek

Publikováno v: EFSA Supporting Publications. 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::396439ed5720e3e612ac3a0f9b2be8f8
https://doi.org/10.2903/sp.efsa.2020.en-1759

Cumulative dietary risk assessment overarching different regulatory silos using a margin of exposure approach: A case study with three chemical silos

Autor: Despo Louca Christodoulou, Neus González, Marie Vanacker, Chris Anagnostopoulos, Urska Blaznik, Amélie Crépet, Marc C. Kennedy, Jacob D. van Klaveren, Angelo Moretto, Bodil Hamborg Jensen, Irena Rehurkova, Jan Dirk te Biesebeek, J. Ruprich, Francesca Metruccio, Corinne Sprong

Publikováno v: Sprong, C, Crépet, A, Metruccio, F, Blaznik, U, Anagnostopoulos, C, Christodoulou, D L, Jensen, B H, Kennedy, M, González, N, Rehurkova, I, Ruprich, J, Dirk Te Biesebeek, J, Vanacker, M, Moretto, A & van Klaveren, J 2020, ' Cumulative dietary risk assessment overarching different regulatory silos using a margin of exposure approach : A case study with three chemical silos ', Food and Chemical Toxicology, vol. 142, 111416 . https://doi.org/10.1016/j.fct.2020.111416

Risk assessment of chemicals occurring in our diet is commonly performed for single chemicals without considering exposure to other chemicals. We performed a case study on risk assessment of combined dietary exposure to chemicals from different regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b7308c82d0eebeb5eb17a705be5c05
https://doi.org/10.1016/j.fct.2020.111416

Dietary Intake and Health Risk Assessment of Polybrominated Diphenyl Ethers in the Netherlands Based on Data Collected in 2004 and 2008

Autor: B. Bokkers, Jan Dirk te Biesebeek, C. Noorlander, M. Zeilmaker, M. Mengelers

Publikováno v: European Journal of Nutrition & Food Safety. 4:535-557

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3782726e62aec29db123f22de621d66
https://doi.org/10.9734/ejnfs/2014/6756