Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer

Autor: Tineke E. Buffart, Jan Hein T.M. van Waesberghe, Henk M.W. Verheul, Jan Dirk Burggraaf, Gerrit A. Meijer, Daoud Sie, Maarten Neerincx, Nicole C.T. van Grieken, Cornelis Verhoef, Bauke Ylstra, Ram C. Shankaraiah, Paul P. Eijk, Mark A. van de Wiel, Floor S.W. Van Der Wolf-De Lijster, Dennis Poel

Publikováno v: PLoS ONE, Vol 13, Iss 8, p e0201809 (2018)
PLoS ONE, 13(8). Public Library of Science
PLoS One (online), 13(8):e0201809. Public Library of Science
PLoS ONE
PLoS ONE, 13(8):e0201809, 1-20. Public Library of Science
Neerincx, M, Poel, D, Sie, D L S, van Grieken, N C T, Shankaraiah, R C, Van Der Wolf-De Lijster, F S W, van Waesberghe, J H T M, Burggraaf, J D, Eijk, P P, Verhoef, C, Ylstra, B, Meijer, G A, van de Wiel, M A, Buffart, T E & Verheul, H M W 2018, ' Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer ', PLoS ONE, vol. 13, no. 8, e0201809, pp. 1-20 . https://doi.org/10.1371/journal.pone.0201809
Neerincx, M, Poel, D, Sie, D L S, van Grieken, N C T, Shankaraiah, R C, van der Wolf-de Lijster, F S W, van Waesberghe, J-H T M, Burggraaf, J-D, Eijk, P P, Verhoef, C, Ylstra, B, Meijer, G A, van de Wiel, M A, Buffart, T E & Verheul, H M W 2018, ' Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer ', PLoS ONE, vol. 13, no. 8, pp. e0201809 . https://doi.org/10.1371/journal.pone.0201809

BACKGROUND: First line chemotherapy is effective in 75 to 80% of patients with metastatic colorectal cancer (mCRC). We studied whether microRNA (miR) expression profiles can predict treatment outcome for first line fluoropyrimidine containing systemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb9348eb9c6ffa77e400ad48f329797
http://www.scopus.com/inward/record.url?scp=85051341690&partnerID=8YFLogxK

Abstract 4928: MiR expression profiles can predict response to systemic treatment in patients with advanced colorectal cancer

Autor: Tineke E. Buffart, Henk M.W. Verheul, Jan Dirk Burggraaf, Maarten Neerincx, Bauke Ylstra, Mark A. van de Wiel, Paul P. Eijk, Nicole C.T. van Grieken, J.H.T.M. van Waesberghe, R Shankaraiah, F. S.W. van der Wolf, Dennis Poel, Cees Verhoef, Daoud L.S. Sie

Publikováno v: Cancer Research. 76:4928-4928

Background and aim: Patients with advanced colorectal cancer (mCRC) are commonly treated with systemic treatment consisting of fluoropyrimidine-based regimens being ineffective in 20-25% of the patients. Currently, selection criteria for patients to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d18786d8245caa9c8f9f2ad78931c04
https://doi.org/10.1158/1538-7445.am2016-4928

Abstract 3073: Deep sequencing of paired colorectal cancers and metastases: Detection of novel miRs and colonization specific miRs

Autor: Maarten Neerincx, Nicole C.T. van Grieken, Bauke Ylstra, Jan-Dirk Burggraaf, Gerrit A. Meijer, Henk L. Dekker, Paul P. Eijk, Henk M.W. Verheul, Tineke E. Buffart, Mark A. van de Wiel, Daoud Sie, Begonia Diosdado

Publikováno v: Cancer Research. 73:3073-3073

INTRODUCTION: Biomarkers are increasingly used for selecting the most optimal therapy for each patient. Genetic information of a primary tumor is often used to guide therapy selection. MiRs have recently been recognized as promising candidate biomark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c916f7ca3082d150e930e44ccf1269b5
https://doi.org/10.1158/1538-7445.am2013-3073