Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jan Bugajski"'
Publikováno v:
Neurotoxicity Research
The nitric oxide (NO) pathway in the brain is involved in response to psychosocial stressors. The aim of this study was to elucidate the role of nNOS and iNOS in the prefrontal cortex (PFC), hippocampus (HIP), and hypothalamus (HYPO) during social is
Publikováno v:
Pharmacological Reports. 68:1178-1196
Background The aim of this study was to compare the expression of interleukin-1β (IL-1β), neuronal nitric oxide synthase (nNOS) and inducible nitric oxide synthase (iNOS) in the prefrontal cortex (PFC), hippocampus (HIP) and hypothalamus (HT) durin
Background Social crowding and isolation are recognized as major stressors and risk factors for development of psychiatric disorders. Chronic isolation stress (IS) and crowding stress (CS) activate neuroendocrine and neurochemical mechanisms, that ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685ee31ebcc7bbe3deaf03c900d8846e
https://ruj.uj.edu.pl/xmlui/handle/item/120663
https://ruj.uj.edu.pl/xmlui/handle/item/120663
Publikováno v:
Brain Research. 817:220-225
Putative involvement of endogenous nitric oxide (NO) in the corticotropin-releasing hormone (CRH, 1 microg/kg i.p.)- and vasopressin (AVP, 5 microg/kg i.p.)-induced ACTH and corticosterone secretion was investigated in both non-stressed and crowded r
Publikováno v:
Pharmacological reports : PR. 65(6)
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis is accepted as one of the fundamental biological mechanisms that underlie major depression. This hyperactivity is caused by diminished feedback inhibition of glucocorticoid (GC)-induced r
Publikováno v:
Pharmacological reports : PR. 65(5)
Background Disruption of the glucocorticoid negative feedback system evoked in animals by chronic stress can be induced by downregulation of glucocorticoid receptors (GRs) in several brain regions. In the present study, the dynamics of the changes in
Publikováno v:
Life Sciences. 59:1157-1164
The role of prostaglandins (PGs) in stimulation of the hypothalamic-pituitary-adrenal (HPA) axis by adrenergic agonists and catecholamines was investigated in nonanesthetized rats. The cyclooxygenase and PGs synthesis inhibitor indomethacin was given
Publikováno v:
Brain Research. 681:223-228
To evaluate the effect of social crowding stress on the CRH and vasopressin-induced hypothalamic-pituitary-adrenocortical (HPA) response, both those neuropeptides were administered intracerebroventricularly and intraperitoneally to rats crowded for 3
Publikováno v:
Pharmacological reports : PR. 64(6)
Background Restraint stress (RS) markedly increases interleukin 1-β (IL-1β) generation in brain structures involved in hypothalamic-pituitary adrenocortical (HPA) axis regulation. The IL-1β-induced transient stimulation of HPA axis activity was pa
Publikováno v:
Pharmacological reports : PR. 64(6)
Background Interleukin-1β (IL-1β), the major cytokine involved in activation of hypothalamic-pituitary-adrenal (HPA) axis modulates both central and peripheral components regulating HPA activity. The role of nitric oxide (NO) generated by neuronal