Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jan Brocher"'
Autor:
Dennis M Defoe, Huiying Rao, David J Harris, Preston D Moore, Jan Brocher, Theresa A Harrison
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226725 (2020)
The cell cycle regulator p27Kip1 is a critical factor controlling cell number in many lineages. While its anti-proliferative effects are well-established, the extent to which this is a result of its function as a cyclin-dependent kinase (CDK) inhibit
Externí odkaz:
https://doaj.org/article/a8c232c372934030b18a7993dee6a358
Autor:
Preston D. Moore, Theresa A. Harrison, Jan Brocher, Dennis M. Defoe, David J. Harris, Huiying Rao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0226725 (2020)
PLoS ONE, Vol 15, Iss 1, p e0226725 (2020)
The cell cycle regulator p27Kip1 is a critical factor controlling cell number in many lineages. While its anti-proliferative effects are well-established, the extent to which this is a result of its function as a cyclin-dependent kinase (CDK) inhibit
Publikováno v:
Chromosoma. 117:147-157
Extensive epidemiological data indicate that inorganic arsenic is associated with several types of human cancer. Nevertheless, the underlying mechanisms are poorly understood. Among its mode of action are the alterations on DNA methylation, which pro
Autor:
Anja Hirmer, Husvinee Sundaramurthi, Jan Brocher, Utz Fischer, Bastian Linder, Jun Yin, Christoph Winkler
Publikováno v:
Investigative ophthalmologyvisual science. 53(8)
PURPOSE In experimental eye research, zebrafish has become a powerful model for human retina disorders. The purpose of the present study is the characterization of antibodies commonly employed in zebrafish models for rod photoreceptor degeneration. M
Autor:
Wiltrud Richter, Tobias Gotterbarm, Wolfgang Wenzel, Leonie Mühlberg, Marc Hoffmann, B. Gutt, Timo Strunk, Elisabeth Seebach, Reinhard Fischer, Stephane Boeuf, Tanja Throm, Jan Brocher
Publikováno v:
Acta biomaterialia, 8 (3), 1037-1047
Hydrophobins are fungal proteins with the ability to form immunologically inert membranes of high stability, properties that makes them attractive candidates for orthopaedic implant coatings. Cell adhesion on the surface of such implants is necessary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c23224bc8ca583712a19e1996048f29
Publikováno v:
Molecular Neurodegeneration, Vol 6, Iss 1, p 56 (2011)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Retinitis pigmentosa (RP) is an inherited eye disease characterized by the progressive degeneration of rod photoreceptor cells. Mutations in pre-mRNA splicing factors including PRPF31 have been identified as cause for RP, raising the quest
Autor:
Christoph Winkler, Sinnakaruppan Mathavan, Holger Dill, Anja Hirmer, Bastian Linder, Hanno J. Bolz, Gek Ping Lee, Bernhard Laggerbauer, Utz Fischer, Jan Brocher
Publikováno v:
Human molecular genetics. 20(2)
Retinitis pigmentosa (RP) is a common hereditary eye disease that causes blindness due to a progressive loss of photoreceptors in the retina. RP can be elicited by mutations that affect the tri-snRNP subunit of the pre-mRNA splicing machinery, but ho
Autor:
Wolfgang Hammerschmidt, Aloys Schepers, Robert Hock, Christian Berens, Dagmar Pich, Jan Brocher, Andreas W. Thomae
Publikováno v:
GBM Annual Spring meeting Mosbach 2008. 2008
Autor:
Dagmar Pich, Aloys Schepers, Jan Brocher, Wolfgang Hammerschmidt, Robert Hock, Mark-Peter Spindler, Christian Berens, Andreas W. Thomae
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 105, 1692-1697 (2008)
In all eukaryotic cells, origins of DNA replication are characterized by the binding of the origin recognition complex (ORC). How ORC is positioned to sites where replication initiates is unknown, because metazoan ORC binds DNA without apparent seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7deb7ab1dabe3c45a6c1558f3d40324e
https://europepmc.org/articles/PMC2234206/
https://europepmc.org/articles/PMC2234206/
Autor:
Alexandra Kukat, Ingo Schäfer, Christian Kukat, Georg Krohne, Ian A. Trounce, Gaetano Villani, Peter Seibel, Jan Brocher
Publikováno v:
Nucleic Acids Res
Nucleic Acids Research
Nucleic Acids Research
Eukaryotic cells devoid of mitochondrial DNA (rho0 cells) were originally generated under artificial growth conditions utilizing ethidium bromide. The chemical is known to intercalate preferentially with the mitochondrial double-stranded DNA thereby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0298f44497c53ed74bbab14f3b0da622
https://hdl.handle.net/21.11116/0000-000B-82AB-1
https://hdl.handle.net/21.11116/0000-000B-82AB-1