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pro vyhledávání: '"Jan Broadbridge"'
Autor:
Hayley Farmer, Peter Charlton, Simon Cocks, Paul Depledge, Richard Faint, Irina Chuckowree, Deanne Thompson, Shouming Wang, Nan Chi Wan, Adrian Folkes, John W. Scott, Jan Broadbridge, Stewart J. Baker, John R. Harrison, Anthony Boyce, Sukhjit Sohal, Timothy Hancox, Warren Miller, Francis Xavier Wilson, Prakash Mistry, Caroline Freathy
Publikováno v:
Journal of Medicinal Chemistry. 47:1339-1350
In our continued effort to identify selective MRP1 modulators, we have developed two novel templates, 3 and 4, through rational drug design by identifying the key pharmacophore interaction at the 7-position of the pyrrolopyrimidine template 1. Furthe