Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jan Brabek"'
Autor:
Sukanya B. Jadhav, Michaela Vondrackova, Petra Potomova, Cristian Sandoval-Acuña, Jana Smigova, Kristyna Klanicova, Daniel Rosel, Jan Brabek, Jan Stursa, Lukas Werner, Jaroslav Truksa
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Multiple studies indicate that iron chelators enhance their anti-cancer properties by inducing NDRG1, a known tumor and metastasis suppressor. However, the exact role of NDRG1 remains controversial, as newer studies have shown that NDRG1 can also act
Externí odkaz:
https://doaj.org/article/babf7f9ee7ce45d2aa4ee3ab2d7ec896
Autor:
Sona Stemberkova‐Hubackova, Renata Zobalova, Maria Dubisova, Jana Smigova, Sarka Dvorakova, Klara Korinkova, Zuzana Ezrova, Berwini Endaya, Kristyna Blazkova, Erik Vlcak, Petra Brisudova, Dan‐Diem Thi Le, Stefan Juhas, Daniel Rosel, Cristina Daniela Kelemen, Dana Sovilj, Eliska Vacurova, Tomas Cajka, Vlada Filimonenko, Lanfeng Dong, Ladislav Andera, Pavel Hozak, Jan Brabek, Zuzana Bielcikova, Jan Stursa, Lukas Werner, Jiri Neuzil
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 3, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/6ffa7e718404400f926a4f1d5c918cd7
Autor:
Qifei Li, Michal Dibus, Alicia Casey, Christina S K Yee, Sara O Vargas, Shiyu Luo, Samantha M Rosen, Jill A Madden, Casie A Genetti, Jan Brabek, Catherine A Brownstein, Shideh Kazerounian, Benjamin A Raby, Klaus Schmitz-Abe, John C Kennedy, Martha P Fishman, Mary P Mullen, Joan M Taylor, Daniel Rosel, Pankaj B Agrawal
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009639 (2021)
ARHGAP42 encodes Rho GTPase activating protein 42 that belongs to a member of the GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) family. ARHGAP42 is involved in blood pressure control by regulating vascular tone. Despite these findings
Externí odkaz:
https://doaj.org/article/aa7ea0af68b8420487248727773f6819
Autor:
Kristyna, Kolouchova, Ondrej, Groborz, Zulfiya, Cernochova, Aneta, Skarkova, Jan, Brabek, Daniel, Rosel, Pavel, Svec, Zenon, Starcuk, Miroslav, Slouf, Martin, Hruby
Publikováno v:
Biomacromolecules. 22(6)
Fluorine-19 magnetic resonance imaging (
Autor:
Manfred Schreiber, Tomáš Macháček, Vojtěch Vajs, Barbora Šmídová, Martin Majer, Jiří Hrdý, Ondřej Tolde, Jan Brábek, Daniel Rösel, Petr Horák
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cancer is still one of the leading causes of death, with an estimated 19.3 million new cases every year. Our paper presents the tumor-suppressing effect of Taenia crassiceps and Mesocestoides corti on B16F10 melanoma, the intraperitoneal application
Externí odkaz:
https://doaj.org/article/c0cd1e571005414dafc8ba25864b2198
Autor:
Lenka Koudelková, Markéta Pelantová, Zuzana Brůhová, Martin Sztacho, Vojtěch Pavlík, Dalibor Pánek, Jakub Gemperle, Pavel Talacko, Jan Brábek, Daniel Rösel
Publikováno v:
eLife, Vol 12 (2023)
The activation of Src kinase in cells is strictly controlled by intramolecular inhibitory interactions mediated by SH3 and SH2 domains. They impose structural constraints on the kinase domain holding it in a catalytically non-permissive state. The tr
Externí odkaz:
https://doaj.org/article/3b1c7c87d3bb4e7db96521db2ea11862
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The ability of cells to switch between different invasive modes during metastasis, also known as invasion plasticity, is an important characteristic of tumor cells that makes them able to resist treatment targeted to a particular invasion mode. Due t
Externí odkaz:
https://doaj.org/article/2e70a053724a4480b7de8718a16840de
Autor:
Jindriska Leischner Fialova, Katerina Hönigova, Martina Raudenska, Lucie Miksatkova, Renata Zobalova, Jiri Navratil, Jana Šmigová, Taraka Ramji Moturu, Tomas Vicar, Jan Balvan, Katerina Vesela, Nikita Abramenko, Zdenek Kejik, Robert Kaplanek, Jaromir Gumulec, Daniel Rosel, Pavel Martasek, Jan Brábek, Milan Jakubek, Jiri Neuzil, Michal Masarik
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113582- (2022)
Mitochondria generate energy and building blocks required for cellular growth and function. The notion that mitochondria are not involved in the cancer growth has been challenged in recent years together with the emerging idea of mitochondria as a pr
Externí odkaz:
https://doaj.org/article/80b69231f27345709bd67e8a884e9d4a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5068 (2023)
MT1-MMP (MMP-14) is a multifunctional protease that regulates ECM degradation, activation of other proteases, and a variety of cellular processes, including migration and viability in physiological and pathological contexts. Both the localization and
Externí odkaz:
https://doaj.org/article/e14354760cc34f8695393fc2b651ed81
Autor:
Magdalena Rašková, Lukáš Lacina, Zdeněk Kejík, Anna Venhauerová, Markéta Skaličková, Michal Kolář, Milan Jakubek, Daniel Rosel, Karel Smetana, Jan Brábek
Publikováno v:
Cells, Vol 11, Iss 22, p 3698 (2022)
Interleukin 6 (IL-6) belongs to a broad class of cytokines involved in the regulation of various homeostatic and pathological processes. These activities range from regulating embryonic development, wound healing and ageing, inflammation, and immunit
Externí odkaz:
https://doaj.org/article/d08376423f0544388824b7da040f3086