Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jan Brüning"'
Autor:
Leonid Goubergrits, Marie Schafstedde, Nikola Cesarovic, Angelika Szengel, Boris Schmitt, Moritz Wiegand, Jan Romberg, Andreas Arndt, Titus Kuehne, Jan Brüning
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract To facilitate pre-clinical animal and in-silico clinical trials for implantable pulmonary artery pressure sensors, understanding the respective species pulmonary arteries (PA) anatomy is important. Thus, morphological parameters describing P
Externí odkaz:
https://doaj.org/article/1648e1c5155c4053aa0a9af7c7f86af6
Autor:
Jan Brüning, Pavlo Yevtushenko, Adriano Schlief, Tobias Jochum, Livia van Gijzen, Sonja Meine, Jan Romberg, Titus Kuehne, Andreas Arndt, Leonid Goubergrits
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
To assess whether in-silico models can be used to predict the risk of thrombus formation in pulmonary artery pressure sensors (PAPS), a chronic animal study using pigs was conducted. Computed tomography (CT) data was acquired before and immediately a
Externí odkaz:
https://doaj.org/article/3cd3f9cb9d224495be3c0b2e7623a5ba
Autor:
Jan Brüning, Peter Kramer, Leonid Goubergrits, Antonia Schulz, Peter Murin, Natalia Solowjowa, Titus Kuehne, Felix Berger, Joachim Photiadis, Viktoria Heide-Marie Weixler
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundDouble outlet right ventricle (DORV) describes a group of congenital heart defects where pulmonary artery and aorta originate completely or predominantly from the right ventricle. The individual anatomy of DORV patients varies widely with m
Externí odkaz:
https://doaj.org/article/51953b9b5d8b40689977eea94eafce43
Autor:
Oliver Beuing, Philipp Berg, Leonid Goubergrits, Andreas Spuler, Florian Hellmeier, Jan Brüning, Sylvia Saalfeld, Ibrahim Erol Sandalcioglu, Naomi Larsen, Jens Schaller
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Objectives Assessing the risk associated with unruptured intracranial aneurysms (IAs) is essential in clinical decision making. Several geometric risk parameters have been proposed for this purpose. However, performance of these parameters has been i
Externí odkaz:
https://doaj.org/article/c576dd2c84864aea8e96a6a16667a5fc
Autor:
Marie Schafstedde, Pavlo Yevtushenko, Sarah Nordmeyer, Peter Kramer, Anastasia Schleiger, Natalia Solowjowa, Felix Berger, Joachim Photiadis, Yaroslav Mykychak, Mi-Young Cho, Stanislav Ovroutski, Titus Kuehne, Jan Brüning
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundUneven hepatic venous blood flow distribution (HFD) to the pulmonary arteries is hypothesized to be responsible for the development of intrapulmonary arteriovenous malformations (PAVM) in patients with univentricular physiology. Thus, achie
Externí odkaz:
https://doaj.org/article/c1661024abe54a81b10f05848819f32a
Autor:
Benedikt Franke, Jan Brüning, Pavlo Yevtushenko, Henryk Dreger, Anna Brand, Benjamin Juri, Axel Unbehaun, Jörg Kempfert, Simon Sündermann, Alexander Lembcke, Natalia Solowjowa, Sebastian Kelle, Volkmar Falk, Titus Kuehne, Leonid Goubergrits, Marie Schafstedde
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: In patients with aortic stenosis, computed tomography (CT) provides important information about cardiovascular anatomy for treatment planning but is limited in determining relevant hemodynamic parameters such as the transvalvular pressure
Externí odkaz:
https://doaj.org/article/a1a1c32868294bf186c861f3f1b074d2
Autor:
Florian Hellmeier, Jan Brüning, Simon Sündermann, Lina Jarmatz, Marie Schafstedde, Leonid Goubergrits, Titus Kühne, Sarah Nordmeyer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2021)
Objectives: Prediction of aortic hemodynamics after aortic valve replacement (AVR) could help optimize treatment planning and improve outcomes. This study aims to demonstrate an approach to predict postoperative maximum velocity, maximum pressure gra
Externí odkaz:
https://doaj.org/article/5f0f049d2db04e52ac9346897d8538ef
Autor:
Joao Filipe Fernandes, Leonid Goubergrits, Jan Brüning, Florian Hellmeier, Sarah Nordmeyer, Tiago Ferreira da Silva, Stephan Schubert, Felix Berger, Titus Kuehne, Marcus Kelm, CARDIOPROOF Consortium
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0168487 (2017)
In aortic coarctation, current guidelines recommend reducing pressure gradients that exceed given thresholds. From a physiological standpoint this should ideally improve the energy expenditure of the heart and thus prevent long term organ damage.The
Externí odkaz:
https://doaj.org/article/731b2b0436474ba3ade401b49e5e68de
Autor:
Jan Brüning
SIMCor (In-Silico testing and validation of Cardiovascular IMplantable devices) has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 101017578.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674c8f4d76882a18e66d4c1f7460e542
Autor:
Sarah Katz, Alfonso Caiazzo, Baptiste Moreau, Ulrich Wilbrandt, Jan Brüning, Leonid Goubergrits, Volker John
Publikováno v:
International Journal for Numerical Methods in Biomedical Engineering. 39
Numerical simulations of pulsatile blood flow in an aortic coarctation require the use of turbulence modeling. This paper considers three models from the class of large eddy simulation (LES) models (Smagorinsky, Vreman, $\boldsymbol{\sigma}$-model) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fef2eed3dc6bcd4fa56ad417abf8169
https://doi.org/10.1002/cnm.3695
https://doi.org/10.1002/cnm.3695