Zobrazeno 1 - 10
of 396
pro vyhledávání: '"Jan Boelens"'
Autor:
Laura G.Y. Rotte, Coco C.H. de Koning, Yvette G.T. Loeffen, Marc B. Bierings, Jaap Jan Boelens, Caroline A. Lindemans, Tom F.W. Wolfs
Publikováno v:
EJC Paediatric Oncology, Vol 4, Iss , Pp 100175- (2024)
Background: Azoles are recommended as antifungal prophylaxis in decreasing the incidence of invasive fungal disease (IFD) in high-risk patients in pediatric oncology, including patients receiving allogeneic hematopoietic cell transplantation (HCT). H
Externí odkaz:
https://doaj.org/article/bed1aed6344440ef8b57bca2205ba559
Autor:
Daphne H. Schoenmakers, Fanny Mochel, Laura A. Adang, Jaap-Jan Boelens, Valeria Calbi, Erik A. Eklund, Sabine W. Grønborg, Francesca Fumagalli, Samuel Groeschel, Caroline Lindemans, Caroline Sevin, Ludger Schöls, Dipak Ram, Ayelet Zerem, Holm Graessner, Nicole I. Wolf
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background For decades, early allogeneic stem cell transplantation (HSCT) has been used to slow neurological decline in metachromatic leukodystrophy (MLD). There is lack of consensus regarding who may benefit, and guidelines are lacking. Cli
Externí odkaz:
https://doaj.org/article/15b67733f9df4ad2852654ef151aeadb
Autor:
Rotte, Laura G.Y., de Koning, Coco C.H., Loeffen, Yvette G.T., Bierings, Marc B., Jan Boelens, Jaap, Lindemans, Caroline A., Wolfs, Tom F.W.
Publikováno v:
In EJC Paediatric Oncology December 2024 4
Autor:
Jaap Jan Boelens, Renier J Brentjens, Young Park, Ruby Freeman, Sanam Shahid, Abdul G Khan, Serena C Mathew, Sydney Souness, Erin R Burns, Jasmine S Um, Kento Tanaka, Winson Cai, Sarah Yoo, Andrew Dunbar, Devin McAvoy, Kinga K Hosszu, Ross L Levine, Ivo C Lorenz, Anthony F Daniyan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background CD33 is a tractable target in acute myeloid leukemia (AML) for chimeric antigen receptor (CAR) T cell therapy, but clinical success is lacking.Methods We developed 3P14HLh28Z, a novel CD33-directed CD28/CD3Z-based CAR T cell derived from a
Externí odkaz:
https://doaj.org/article/b42d94a937d841e2987bd9a5c7486879
Autor:
Murtadha Al‐Saady, Shanice Beerepoot, Bonnie C. Plug, Marjolein Breur, Hristina Galabova, Petra J. W. Pouwels, Jaap‐Jan Boelens, Caroline Lindemans, Peter M. vanHasselt, Ulrich Matzner, Adeline Vanderver, Marianna Bugiani, Marjo S. van derKnaap, Nicole I. Wolf
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 7, Pp 1146-1159 (2023)
Abstract Objective Metachromatic leukodystrophy is a lysosomal storage disease caused by deficient arylsulfatase A. It is characterized by progressive demyelination and thus mainly affects the white matter. Hematopoietic stem cell transplantation may
Externí odkaz:
https://doaj.org/article/451b051a73834de09b3e42f76f2a7a8b
Autor:
Jaap Jan Boelens, Muhammad Umair Mushtaq, Joseph Mcguirk, Aurelie Bauquet, Laura Simons, Pierre Heimendinger, Pierre Gaudeaux, Isabelle Andre, Juliette Paillet, Olivier Negre, Tayebeh-Shabi Soheili, Sebastien Oster, Marcel R.M. van den Brink, Frederic Lehmann, Marina Cavazzana, Miguel-Angel Perales
Publikováno v:
HemaSphere, Vol 7, p e660193c (2023)
Externí odkaz:
https://doaj.org/article/6a28ca3eede643b2ac86473747a8877e
Autor:
Alexandre G. Troullioud Lucas, Jaap Jan Boelens, Susan E. Prockop, Kevin J. Curran, Dorine Bresters, Wouter Kollen, Birgitta Versluys, Marc B. Bierings, Anne Archer, Eric Davis, Elizabeth Klein, Nancy A. Kernan, Caroline A. Lindemans, Andromachi Scaradavou
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundPatients with leukemia relapse after allogeneic hematopoietic cell transplant (HCT) have poor survival due to toxicity and disease progression. A second HCT often offers the only curative treatment.MethodsWe retrospectively reviewed our bi-
Externí odkaz:
https://doaj.org/article/4bbe82594c39483eb049ca274f54e3e9
Autor:
Daphne H. Schoenmakers, Shanice Beerepoot, Sibren van den Berg, Laura Adang, Annette Bley, Jaap-Jan Boelens, Francesca Fumagalli, Wim G. Goettsch, Sabine Grønborg, Samuel Groeschel, Peter M. van Hasselt, Carla E. M. Hollak, Caroline Lindemans, Fanny Mochel, Peter G. M. Mol, Caroline Sevin, Ayelet Zerem, Ludger Schöls, Nicole I. Wolf
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background Metachromatic Leukodystrophy (MLD) is a rare lysosomal disorder. Patients suffer from relentless neurological deterioration leading to premature death. Recently, new treatment modalities, including gene therapy and enzyme replacem
Externí odkaz:
https://doaj.org/article/8c393f5208e146328f0af2066de15352
Autor:
Vania Lo Presti, Annelisa M. Cornel, Maud Plantinga, Ester Dünnebach, Jurgen Kuball, Jaap Jan Boelens, Stefan Nierkens, Niek P. van Til
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 357-368 (2021)
Adoptive T cell therapy utilizing tumor-specific autologous T cells has shown promising results for cancer treatment. However, the limited numbers of autologous tumor-associated antigen (TAA)-specific T cells and the functional aberrancies, due to di
Externí odkaz:
https://doaj.org/article/437a3fa6e3444d1fa4601d5b93d4d03b
Autor:
Brigitte W. M. Willemse, Saskia N. van der Crabben, Wilhelmina S. Kerstjens-Frederikse, Wim Timens, Joris M. van Montfrans, Caroline A. Lindemans, Jaap Jan Boelens, Marije P. Hennus, Gijs van Haaften
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-7 (2021)
Abstract We report five patients with lung disease immuno-deficiency and chromosome breakage syndrome (LICS) but without recurrent infections and severe immunodeficiency. One patient had extended survival to 6.5 years. Hematopoietic stem-cell transpl
Externí odkaz:
https://doaj.org/article/8166af30d2064f568de6a325ebb2fea6