Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jan Blecha"'
Autor:
Sandra Lettlova, Veronika Brynychova, Jan Blecha, David Vrana, Magdalena Vondrusova, Pavel Soucek, Jaroslav Truksa
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 6, Pp 2601-2615 (2018)
Background/Aims: MiRNA-301a-3p is an oncogenic miRNA whose expression is associated with tumor development, metastases and overall poor prognosis. Estrogen receptor α (ERα) is one of the estrogen hormone-activated transcription factors, which regul
Externí odkaz:
https://doaj.org/article/8cce9a721faa4e2a9c4187fb0bbb2157
Autor:
Silvia Magalhaes-Novais, Jan Blecha, Ravindra Naraine, Jana Mikesova, Pavel Abaffy, Alena Pecinova, Mirko Milosevic, Romana Bohuslavova, Jan Prochazka, Shawez Khan, Eliska Novotna, Radek Sindelka, Radek Machan, Mieke Dewerchin, Erik Vlcak, Joanna Kalucka, Sona Stemberkova Hubackova, Ales Benda, Jermaine Goveia, Tomas Mracek, Cyril Barinka, Peter Carmeliet, Jiri Neuzil, Katerina Rohlenova, Jakub Rohlena
Publikováno v:
Autophagy
Mitochondrial oxidative phosphorylation (OXPHOS) generates ATP, but OXPHOS also supports biosynthesis during proliferation. In contrast, the role of OXPHOS during quiescence, beyond ATP production, is not well understood. Using mouse models of induci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d30e591e3fe4d30a7efe94fa0e314ac
https://lirias.kuleuven.be/handle/20.500.12942/692631
https://lirias.kuleuven.be/handle/20.500.12942/692631
Autor:
Jan Blecha, Václav Salcman
Publikováno v:
Studia Kinanthropologica. 21:277-282
The aim of this study is to assess the quality of stereoscopic vision in children of younger school age (n = 60) with regard to sports activities (handball, swimming), regularly performed by these children. In order to determine the level of stereops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::268d58b6e046d794f37bc8ed708a8688
https://doi.org/10.32725/sk.2020.061
https://doi.org/10.32725/sk.2020.061
Autor:
Jan Blecha, David Vrána, Sandra Lettlova, Pavel Soucek, Magdalena Vondrusova, Veronika Brynychova, Jaroslav Truksa
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 6, Pp 2601-2615 (2018)
Background/Aims: MiRNA-301a-3p is an oncogenic miRNA whose expression is associated with tumor development, metastases and overall poor prognosis. Estrogen receptor α (ERα) is one of the estrogen hormone-activated transcription factors, which regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b10312e22b653ff4565b8907d262fb
https://doi.org/10.1159/000489687
https://doi.org/10.1159/000489687
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
Good mental preparation of an athlete plays an important role in achieving optimal sports results. An athlete who enters a competition should not feel fatigue resulting from intense physical exercise. Therefore, new and effective methods are being so
Externí odkaz:
https://doaj.org/article/354d5f5262d34656999b211e2db4c430
Autor:
Jan Blecha, Jiri Neuzil, Jakub Rohlena, Silvia Magalhaes Novais, Sandra Lettlova, Katerina Rohlenova, Hans Zischka, Eliska Novotna, Sabine Schmitt
Publikováno v:
Free Radical Biology and Medicine. 112:253-266
Mitochondrial electron transport chain (ETC) targeting shows a great promise in cancer therapy. It is particularly effective in tumors with high ETC activity where ETC-derived reactive oxygen species (ROS) are efficiently induced. Why modern ETC-targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84275645f1321b185a66055132242ab0
https://doi.org/10.1016/j.freeradbiomed.2017.07.033
https://doi.org/10.1016/j.freeradbiomed.2017.07.033
Autor:
Berwini Endaya, Jiri Neuzil, Jiri Cerny, Renata Zobalova, Pavel Hozák, Bing Yan, Tomáš Špaček, Petr Jezek, Karishma Sachaphibulkij, Jakub Rohlena, Jan Blecha, Katerina Rohlenova, Lan-Feng Dong, Margaryta Sobol, Lukas Werner, Jacob Goodwin, Magdalena Vondrusova, Elham Alizadeh Pesdar, Maria Nga Nguyen, Jan Stursa, Ayenachew Bezawork-Geleta, Jaroslav Truksa
Publikováno v:
Antioxidants & Redox Signaling. 26:84-103
Aims: Expression of the HER2 oncogene in breast cancer is associated with resistance to treatment, and Her2 may regulate bioenergetics. Therefore, we investigated whether disruption of the electron transport chain (ETC) is a viable strategy to elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e2daaac3c4cca08da325ce09bf1eba
https://doi.org/10.1089/ars.2016.6677
https://doi.org/10.1089/ars.2016.6677
Publikováno v:
Free Radical Biology and Medicine. 165:46
Mitochondrial oxidative phosphorylation (OXPHOS) generates ATP, but also has other important roles that are ATP-independent. In proliferating cells OXPHOS is required for pyrimidine synthesis, but in non-proliferating cells its ATP-unrelated function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b2d3ccf8ae5ed7e703bf18cbb2c695b
https://doi.org/10.1016/j.freeradbiomed.2020.12.389
https://doi.org/10.1016/j.freeradbiomed.2020.12.389
Autor:
Katerina, Rohlenova, Karishma, Sachaphibulkij, Jan, Stursa, Ayenachew, Bezawork-Geleta, Jan, Blecha, Berwini, Endaya, Lukas, Werner, Jiri, Cerny, Renata, Zobalova, Jacob, Goodwin, Tomas, Spacek, Elham, Alizadeh Pesdar, Bing, Yan, Maria Nga, Nguyen, Magdalena, Vondrusova, Margaryta, Sobol, Petr, Jezek, Pavel, Hozak, Jaroslav, Truksa, Jakub, Rohlena, Lan-Feng, Dong, Jiri, Neuzil
Publikováno v:
Antioxidantsredox signaling. 26(2)
Expression of the HER2 oncogene in breast cancer is associated with resistance to treatment, and Her2 may regulate bioenergetics. Therefore, we investigated whether disruption of the electron transport chain (ETC) is a viable strategy to eliminate He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65a2d866b52d9e39ea542977ce0db2bf
https://pubmed.ncbi.nlm.nih.gov/27392540
https://pubmed.ncbi.nlm.nih.gov/27392540
Publikováno v:
Free Radical Biology and Medicine. 120:S79
Mitochondria are organelles central to energy metabolism and cell death. In the present work we investigated the role of functional electron transfer chain (ETC) in cell's adaptation to the quiescent state, using ETC-deficient (ρ0 cells) endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efdd7f0faf451e75abf5e413a3e287f9
https://doi.org/10.1016/j.freeradbiomed.2018.04.262
https://doi.org/10.1016/j.freeradbiomed.2018.04.262