Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jan Bert, van Klinken"'
Autor:
Yorrick R.J. Jaspers, Sven W. Meyer, Mia L. Pras-Raves, Inge M.E. Dijkstra, Eric J.M. Wever, Adrie D. Dane, Jan-Bert van Klinken, Gajja S. Salomons, Riekelt H. Houtkooper, Marc Engelen, Stephan Kemp, Michel Van Weeghel, Frédéric M. Vaz
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 6, Pp 100567- (2024)
Lipids play pivotal roles in an extensive range of metabolic and physiological processes. In recent years, the convergence of trapped ion mobility spectrometry and MS has enabled 4D-lipidomics, a highly promising technology for comprehensive lipid an
Externí odkaz:
https://doaj.org/article/deec6247e3684b2caada44c6c89b50f6
Autor:
Edgar E. Nollet, Sila Algül, Max Goebel, Saskia Schlossarek, Nicole N. van der Wel, Judith J.M. Jans, Mark A. van de Wiel, Jaco C. Knol, Thang V. Pham, Sander R. Piersma, Richard de Goeij-de Haas, Jill Hermans, Jan Bert van Klinken, Michel van Weeghel, Riekelt H. Houtkooper, Lucie Carrier, Connie R. Jimenez, Diederik W.D. Kuster, Jolanda van der Velden
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 6, Iss , Pp 100050- (2023)
Background and aim: Phenotypic expression of hypertrophic cardiomyopathy (HCM) and disease course are associated with unfavorable metabolic health. We investigated if Western diet (WD) feeding is sufficient to trigger cardiac hypertrophy and dysfunct
Externí odkaz:
https://doaj.org/article/a35423357cb242d7a31ba3d7bed60292
Autor:
Robin van Eenige, Wietse In het Panhuis, Milena Schönke, Céline Jouffe, Thomas H. Devilee, Ricky Siebeler, Trea C.M. Streefland, Hetty C.M. Sips, Amanda C.M. Pronk, Ruben H.P. Vorderman, Hailiang Mei, Jan Bert van Klinken, Michel van Weeghel, Nina H. Uhlenhaut, Sander Kersten, Patrick C.N. Rensen, Sander Kooijman
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101497- (2022)
Objective: Brown adipose tissue (BAT) burns fatty acids (FAs) to produce heat, and shows diurnal oscillation in glucose and triglyceride (TG)-derived FA-uptake, peaking around wakening. Here we aimed to gain insight in the diurnal regulation of metab
Externí odkaz:
https://doaj.org/article/06c92daf305441edabcfb8bb607a0144
Autor:
Joris Deelen, Johannes Kettunen, Krista Fischer, Ashley van der Spek, Stella Trompet, Gabi Kastenmüller, Andy Boyd, Jonas Zierer, Erik B. van den Akker, Mika Ala-Korpela, Najaf Amin, Ayse Demirkan, Mohsen Ghanbari, Diana van Heemst, M. Arfan Ikram, Jan Bert van Klinken, Simon P. Mooijaart, Annette Peters, Veikko Salomaa, Naveed Sattar, Tim D. Spector, Henning Tiemeier, Aswin Verhoeven, Melanie Waldenberger, Peter Würtz, George Davey Smith, Andres Metspalu, Markus Perola, Cristina Menni, Johanna M. Geleijnse, Fotios Drenos, Marian Beekman, J. Wouter Jukema, Cornelia M. van Duijn, P. Eline Slagboom
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Biomarkers that predict mortality are of interest for clinical as well as research applications. Here, the authors analyze metabolomics data from 44,168 individuals and identify key metabolites independently associated with all-cause mortality risk.
Externí odkaz:
https://doaj.org/article/6923daf567204a5eb33b751c0974e159
Autor:
Tariq O. Faquih, Jan Bert van Klinken, Ruifang Li‐Gao, Raymond Noordam, Diana van Heemst, Sebastiaan Boone, Patricia A. Sheridan, Gregory Michelotti, Hildo Lamb, Renée de Mutsert, Frits R. Rosendaal, Astrid van Hylckama Vlieg, Ko Willems van Dijk, Dennis O. Mook‐Kanamori
Publikováno v:
Liver International, 43(7), 1458-1472. WILEY
Liver international. Wiley-Blackwell
Liver international. Wiley-Blackwell
Background and Aims: Non-alcoholic fatty liver disease (NAFLD) is characterized by the pathological accumulation of triglycerides in hepatocytes and is associated with insulin resistance, atherogenic dyslipidaemia and cardiometabolic diseases. Thus f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395cad114ce54235f95d47ab58cbb0f2
http://hdl.handle.net/1887/3619448
http://hdl.handle.net/1887/3619448
Autor:
Wenyi Wang, Ephrem Baraki Tesfay, Jan Bert van Klinken, Ko Willems van Dijk, Andrzej Bartke, Diana van Heemst, Raymond Noordam
Publikováno v:
International Journal of Epidemiology, 51(6), 1874-1885. OXFORD UNIV PRESS
International journal of epidemiology, 51(6), 1874-1885. Oxford University Press
International journal of epidemiology, 51(6), 1874-1885. Oxford University Press
Background There is inconsistent evidence for the causal role of serum insulin-like growth factor-1 (IGF-1) concentration in the pathogenesis of human age-related diseases such as type 2 diabetes (T2D). Here, we investigated the association between I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba83699d073454e927bbb11a7ac5e2f
https://hdl.handle.net/1887/3503689
https://hdl.handle.net/1887/3503689
Autor:
Ayşe Demirkan, Peter Henneman, Aswin Verhoeven, Harish Dharuri, Najaf Amin, Jan Bert van Klinken, Lennart C Karssen, Boukje de Vries, Axel Meissner, Sibel Göraler, Arn M J M van den Maagdenberg, André M Deelder, Peter A C 't Hoen, Cornelia M van Duijn, Ko Willems van Dijk
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004835 (2015)
Metabolite quantitative traits carry great promise for epidemiological studies, and their genetic background has been addressed using Genome-Wide Association Studies (GWAS). Thus far, the role of less common variants has not been exhaustively studied
Externí odkaz:
https://doaj.org/article/bc9c29efd0e144fa96cfeee07c156383
Autor:
Jan-Bert van Klinken, Laura G.M. Janssen, Sander Kooijman, Jari A. van der Eijk, Lisanne A. Overduin, Michel van Weeghel, Andrew G. Webb, Ko Willems van Dijk, Tamer Coskun, Jonatan R. Ruiz, Kimberly J. Nahon, Ingrid M. Jazet, Frédéric M. Vaz, Jedrzej Burakiewicz, Oleh Dzyubachyk, Hermien E. Kan, Mariëtte R. Boon, Manu P. Bilsen, Patrick C.N. Rensen, Aashley S.D. Sardjoe Mishre, Kani Botani, Borja Martinez-Tellez, Jimmy F.P. Berbée
Publikováno v:
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Diabetes, Obesity & Metabolism
Diabetes, obesity & metabolism, 22(11), 2032-2044. Wiley-Blackwell
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Diabetes, Obesity and Metabolism, 22(11), 2032-2044. WILEY
Universidad de Granada (UGR)
Diabetes, Obesity & Metabolism
Diabetes, obesity & metabolism, 22(11), 2032-2044. Wiley-Blackwell
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Diabetes, Obesity and Metabolism, 22(11), 2032-2044. WILEY
Aim: To compare the effects of cold exposure and the β3-adrenergic receptor agonist mirabegron on plasma lipids, energy expenditure and brown adipose tissue (BAT) activity in South Asians versus Europids. Materials and Methods: Ten lean Dutch South
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9bd86597fa3208fd611614e9746d05
https://doi.org/10.1111/dom.14120
https://doi.org/10.1111/dom.14120
Autor:
Kani Botani, Borja Martinez-Tellez, Mariëtte R. Boon, Frédéric M. Vaz, Kimberly J. Nahon, Ingrid M. Jazet, Laura G.M. Janssen, Hermien E. Kan, Patrick C.N. Rensen, Oleh Dzyubachyk, Jari A. van der Eijk, Lisanne A. Overduin, Aashley S. D. SardjoeMishre, Ko Willems van Dijk, Andrew G. Webb, Michel van Weeghel, Tamer Coskun, Manu P. Bilsen, Jedrzej Burakiewicz, Sander Kooijman, Jan-Bert van Klinken, Jimmy F.P. Berbée, Jonatan R. Ruiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b525d343bee02ccc6db567d717e91adf
https://doi.org/10.1111/dom.14120/v2/response1
https://doi.org/10.1111/dom.14120/v2/response1
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36162 (2012)
Physical activity (PA) is a main determinant of total energy expenditure (TEE) and has been suggested to play a key role in body weight regulation. However, thus far it has been challenging to determine what part of the expended energy is due to acti
Externí odkaz:
https://doaj.org/article/604027b175b94cda83f0df8061458dc4