Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Jan B. De Vries"'
1
Extremely potent orally active benzo[g]quinoline analogue of the dopaminergic prodrug
Autor: Håkan Wikström, Danyang Liu, Durk Dijkstra, Jan B. De Vries, Bastiaan Johan Venhuis
Publikováno v: Journal of Medicinal Chemistry, 49(4), 1494-1498. AMER CHEMICAL SOC
Enone prodrugs of dopaminergic catecholamines represent a new type of prodrug in the research area of dopamine agonists. Here, we demonstrate the first benzo[g]quinoline-derived enone that induces potent dopamine agonist effects similar to arninotetr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c10080dca6bd542c4215a5388bffc1
https://doi.org/10.1021/jm051111h
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2
Synthesis and pharmacological evaluation of 5,6,7,8‐tetrahydro‐6‐[propyl[2‐(2‐thienyl)ethyl]amino]‐1,2‐naphthalenediol: A novel non‐selective dopamine‐receptor agonist
Autor: Jan B. De Vries, Cor J. Grol, Swier Copinga, Alan S. Horn, Durk Dijkstra
Publikováno v: Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands Chemical Society, 112(2), 137-142. ELSEVIER SCIENCE BV
Based on the hypothesis that simultaneous stimulation of dopamine-D1 and -D2 receptors could be beneficial for the treatment of Parkinson's disease7,13, we prepared 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1,2-naphthalenediol (PTAT, 4),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8053ce20a3a629b233e4976308682636
https://hdl.handle.net/11370/8dc2f720-7bd9-4acb-ae97-17f39ccf24a9
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3
A novel synthesis and pharmacological evaluation of a potential dopamine D1/D2 agonist: 1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol
Autor: Jan B. De Vries, Hakan Wikstrom, Danyang Liu, Durk Dijkstra
Publikováno v: Bioorganic & Medicinal Chemistry, 16(6), 3438-3444. PERGAMON-ELSEVIER SCIENCE LTD
Previously, we have demonstrated that enone prodrugs of dopaminergic catecholamines represent a new type of dopamine (DA) agonist. Trans-1-propyl-1,2, 3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol (TL-334), the active form oftrans-1-propyl-2,3,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec57312728adfd37c93a8468caa4d221
https://pubmed.ncbi.nlm.nih.gov/18313303
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4
Evidence for activation of histamine H3 autoreceptors during handling stress in the prefrontal cortex of the rat
Autor: Thomas I. F. H. Cremers, Jan B. De Vries, Hans Liefers, Nan Tran, Ben H.C. Westerink, Peter de Boer
Publikováno v: Synapse (New York, N.Y.). 43(4)
On-line microdialysis of histamine in 10-min samples of the prefrontal cortex of the conscious rat is described. The HPLC-fluorescent assay for histamine in dialysates has been significantly simplified by using only one postcolumn reagent line instea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce56f7b065a43a4d5028128e5873df6
https://pubmed.ncbi.nlm.nih.gov/11835518
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5
Increase in dopamine release from the nucleus accumbens in response to feeding: a model to study interactions between drugs and naturally activated dopaminergic neurons in the rat brain
Autor: Jan B. De Vries, A. C. H. Teisman, Ben H.C. Westerink
Publikováno v: Naunyn-Schmiedebergs Archives of Pharmacology, 349(3), 230-235. SPRINGER
The aim of the present study was to investigate the interactions between the in vivo release of dopamine and certain drugs, during conditions of increased dopaminergic activity. Dopaminergic neurons in the nucleus accumbens were activated by feeding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320f1caf32a640a7dc79fec9c69287bc
https://pubmed.ncbi.nlm.nih.gov/8208301
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7
The use of in vivo brain dialysis of dopamine, acetylcholine, aminoacids and lactic acid in studies on the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
Autor: G. Damsma, Hans Rollema, Ben H.C. Westerink, Geoman L. Kranenborg, Jan B. De Vries, Alan S. Horn, Werner G. Kuhr
Publikováno v: Toxicology, 49(2-3), 503-511. ELSEVIER IRELAND LTD
The use of intracerebral brain dialysis in freely moving rats in neurochemical and neurotoxicological research is discussed and exemplified by studies on the neurotoxin MPTP. Intrastriatal administration of its toxic metabolite MPP+, via the dialysis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71725c31973db7ad509cce5ee0221ba8
https://doi.org/10.1016/0300-483x(88)90036-4
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8
The enantiomers of the D-2 dopamine receptor agonist N-0437 discriminate between pre- and postsynaptic dopamine receptors
Autor: Jan B. De Vries, Pieter G. Tepper, Jan Van der Weide, Maartje E.C. Tendijck, Margarita L. Dubocovich, Alan S. Horn
Publikováno v: European Journal of Pharmacology, 146(2-3), 319-326. ELSEVIER SCIENCE BV
The (+) and (-) enantiomers of the substituted 2-aminotetralin, N-0437 were evaluated in vivo for their dopaminergic activity, using biochemical as well as behavioural models. In presynaptic models, i.e. antagonism of gamma-butyrolactone-induced dihy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6eea734e3162ce9a04e7350903a834
https://research.rug.nl/en/publications/35e04300-c60d-4883-b673-9f99ceebb944
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9
Further in vitro and in vivo studies with the putative presynaptic dopamine agonist N,N-dipropyl-7-hydroxy-2-aminotetralin
Autor: Jan B. De Vries, Johann W. Wiechers, Theo B.A. Mulder, Cor J. Grol, Alan S. Horn, Durk Dijkstra
Publikováno v: Naunyn-Schmiedebergs Archives of Pharmacology, 336(5), 494-501. SPRINGER
The in vitro binding of the putative dopamine autoreceptor agonist [3H]DP-7-ATN to rat striatal membrane homogenates was investigated. The maximum number of binding sites Bmax was 497.5 +/- 50.2 fmol/mg protein and the affinity constant KD was 8.3 +/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feba71bf450e006b5843d6d75498237b
https://doi.org/10.1007/BF00169305
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10
Dutch Pharmacological Meeting 1984
Autor: J. Mooy, Margot J. H. de Reus, G. R. Mohn, Ch. M. Leijdekkers, J. Van Harten, H. J. M. Salden, J. G. Loeber, M. Raghoebar, R. J. M. ten Berge, Joop S. de Graaf, W. de Jong, E. M. van der Beek, C. A. M. Van Ginneken, P. W. Wester, J. B. M. van Driel, Peter M. Edelbroek, Hans Rollema, C. A. J. M. Vulders, D. J. Touw, J. J. Grote, Pramod R. Saxena, E. I. Krajnc, Frans P. Nijkamp, J. Kreukniet, Frederik A. de Wolff, H. Burbach, F. C. Hillen, W. Kruizinga, F. W. J. Gribnau, P. H. Hofman, M. J. A. M. Franssen, K. H. Rahn, Frans G. M. Russel, Hans J. Steenbergen, E. Laban, D.J. de Wildt, H. Wollersheim, Npe Vermeulen, H. M. E. Scheres, M. Van Der Graaff, L. R. Remeyer, E. Ronald de Kloet, M. C. M. Rijk, H. J. H. Salden, F. J. Jongeneelen, Theo Mulder, H. E. Sluiter, T. Bultsma, A. B. M. Klaassen, M. v. Baak, J. A. H. Raaijmakers, A. J. van Rozen, J. F. M. Nouws, R. A. P. Koene, N. Verbeke, H. L. G. H. Tiemessen, B. J. L. Kothuis, Cor J. de Vos, R.P. Bos, J. G. P. Peters, Frans W. H. M. Merkus, C. E. M. Zoetemelk, Mjmc Thoolen, M. R. Linschoten, P. T. A. Schellekens, W. Buijs, Th. Thien, H. Th. M. Folgering, L. Conings, D. K. F. Meijer, J. J. Cox van Put, J. De Gier, Ferdi Engels, W. Kateman, P. Lomax, F. Th. M. Huysmans, F. X. R. van Leeuwen, C. J. Van Boxtel, Y. Tan, M. J. Krielaart, G. A. Charbon, J. G. Vos, B. J. 't Hart, J. Jelinek, P. van Heuven-Nolsen, W. J. Wijnands, A. de Jonge, G. R. Bolt, U. R. Tjaden, K. U. Leuven, Durk Oijkstra, Lambert H.M. Janssen, C. M. M. Veldhoven, H. M. N. Nievelstein, E. J. AriËns, H. M. J. Roelofs, A. van 't Laar, L. H. van den Berg, H. N. Doods, F. Corstens, M. v. Hengstum, O. Driessen, R. Groothedde, G. B. van der Voet, W. Kuijpers, A. de Klerk, E. Schönbaum, D. D. Breimer, B. van Ommen, C. A. van der Heijden, M. v. Hooff, E. A. De Bruijn, Hendrik Timmerman, L. C. M. Baars, P van Brummelen, C. T. A. Evelo, A. J. Beld, H. H. W. Thljssen, G. Aué, R. van Doorn, H. A. M. G. Vaessen, J. Fennis, Theo B.A. Mulder, W. v. d. Broek, G. K. Terpstra, A. T. van Oosterom, Cor J. Grol, R. A. Lefebvre, P. A. Van Zwieten, A. C. Wouterse, Rob B. M. Anzion, J. F. Rodrigues De Miranda, C. Neef, R. S. Oosting, A. Van Der Gen, C. H. Kleinbloesem, Marian W. Tijhuis, Yechiel A. Hekster, H. A. J. Struyker Boudier, C. L. A. van Herwaarden, Bob Wilffert, Dora Mastebroex, E. A. van der Velde, A. S. P. M. Breed, H. L. M. Siero, Gerard van Aalst, J. L. G. Theuws, F. A. De Wolff, J. Rozing, E. I. Krajc, R. H. B. Meyboom, M. A. M. ten Broeke, J. Festen, P.J.L. van Gemert, A. P. I. Jzerman, Hans Wynberg, Alan Horn, H. J. E. Reeuwijk, B. O Osterhuis, R. Dorlas, P. A. M. Peeters, J. Willemsen, L. M. de Brauw, Jan B. de Vries, L. B. A. van de Putte, Alan S. Horn, J. H. Canton, H. J. E. M. Reeuwijk, M. Schols, J. A. M. Raaijmakers, Marcus Bogaert, J. van Noordwijk, Durk Dijkstra, P.Th. Henderson, Peter P. Koopmans, J. W. J. Lammers, T. B. Vree, C. J. H. van de Velde, C. J. Van Koppen, Bernard Hazelhoff, Jaap Wilting, H. M. Pinedo, W. Kuypers, C. M. Ruland, H. A. J. Struyker-Boudier, J. M. Neis, P. B. M. W. M. Timmermans, H. O. Kalkman, P. R. M. Kerklaan, P. A. F. Jansen, J. Peter, J. H. Koeman, H. J. Huidekoper, Mj Mathy, A.F. De Schaepdryver, R.A.M. van der Hoeven, Jos F.M. Smits, Tjeerd van den Berg, E. H. den Tonkelaar, J. W. M. Lenders, P. Sandor, C. A. v. d. Heijden, G. A. Wassink, O. Castelein, P. H. Th. J. Slee
Publikováno v: Pharmaceutisch Weekblad. 6:163-184
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f0feb23f7a988a0d11f3171454f7aae1
https://doi.org/10.1007/bf01954045
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