Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jan Böhning"'
Autor:
Jan Böhning, Miles Graham, Suzanne C. Letham, Luke K. Davis, Ulrike Schulze, Phillip J. Stansfeld, Robin A. Corey, Philip Pearce, Abul K. Tarafder, Tanmay A. M. Bharat
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Inoviruses are filamentous phages infecting numerous prokaryotic phyla. Inoviruses can self-assemble into mesoscale structures with liquid-crystalline order, termed tactoids, which protect bacterial cells in Pseudomonas aeruginosa biofilms f
Externí odkaz:
https://doaj.org/article/6511d5149f124097b4448d6c2a9651f0
Autor:
Jan Böhning, Mnar Ghrayeb, Conrado Pedebos, Daniel K. Abbas, Syma Khalid, Liraz Chai, Tanmay A. M. Bharat
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Fibres formed by protein TasA are important components of the extracellular matrix in biofilms developed by the bacterium Bacillus subtilis. Here, Böhning et al. use electron cryomicroscopy and other techniques to show how TasA globular monomers ass
Externí odkaz:
https://doaj.org/article/b0538577ebde418a875b0e611cff7203
Autor:
Jan Böhning, Adrian W Dobbelstein, Nina Sulkowski, Kira Eilers, Andriko von Kügelgen, Abul K Tarafder, Sew-Yeu Peak-Chew, Mark Skehel, Vikram Alva, Alain Filloux, Tanmay A M Bharat
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011177 (2023)
Chaperone-Usher Pathway (CUP) pili are major adhesins in Gram-negative bacteria, mediating bacterial adherence to biotic and abiotic surfaces. While classical CUP pili have been extensively characterized, little is known about so-called archaic CUP p
Externí odkaz:
https://doaj.org/article/6a6982262fb3416ba14362c4e2da864d
Publikováno v:
Faraday Discussions. 240:67-80
An increasing number of studies on biomolecular function indirectly combine mass spectrometry (MS) with imaging techniques such as cryo electron microscopy (cryo-EM). This approach allows information on the homogeneity, stoichiometry, shape, and inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c02f8ea6e1fc6e0e69041999fe2839
https://doi.org/10.1039/d2fd00065b
https://doi.org/10.1039/d2fd00065b
Autor:
Jan Böhning, Miles Graham, Suzanne C. Letham, Luke K. Davis, Ulrike Schulze, Phillip J. Stansfeld, Robin A. Corey, Philip Pearce, Abul K. Tarafder, Tanmay A. M. Bharat
SummaryInoviruses are abundant filamentous phages infecting numerous prokaryotic phyla, where they can symbiotically promote host fitness and increase bacterial virulence. Due to their unique properties, inoviruses have also been utilised in biotechn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd438dc0d78d32bd1c25a235845a2dec
https://doi.org/10.1101/2022.12.13.520211
https://doi.org/10.1101/2022.12.13.520211
Autor:
Tim K Esser, Jan Böhning, Paul Fremdling, Mark T Agasid, Adam Costin, Kyle Fort, Albert Konijnenberg, Joshua D Gilbert, Alan Bahm, Alexander Makarov, Carol V Robinson, Justin L P Benesch, Lindsay Baker, Tanmay A M Bharat, Joseph Gault, Stephan Rauschenbach
Publikováno v:
PNAS Nexus. 1
Despite tremendous advances in sample preparation and classification algorithms for electron cryomicroscopy (cryo-EM) and single-particle analysis (SPA), sample heterogeneity remains a major challenge and can prevent access to high-resolution structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c352879bca28425ef552530ce166d05a
https://doi.org/10.1093/pnasnexus/pgac153
https://doi.org/10.1093/pnasnexus/pgac153
Autor:
Jan Böhning, Mnar Ghrayeb, Conrado Pedebos, Daniel K. Abbas, Syma Khalid, Liraz Chai, Tanmay A. M. Bharat
Many bacteria in nature exist in multicellular communities termed biofilms. Cells within biofilms are embedded in a primarily self-secreted extracellular polymeric matrix that provides rigidity to the biofilm and protects cells from chemical and mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55e0332428198edc517db62c4301a0fb
https://doi.org/10.1101/2022.03.14.484220
https://doi.org/10.1101/2022.03.14.484220
Autor:
Reika Watanabe, O. Donosa, Andrew K. Shiau, M. Matyszewski, Andres E. Leschziner, John Salogiannis, C. K. Deniston, Indrajit Lahiri, David Snead, Samara L. Reck-Peterson, Jan Böhning, Elizabeth Villa, Stefan Knapp, Sebastian Mathea
Publikováno v:
Nature
Leucine-rich repeat kinase 2 (LRRK2) is the most commonly mutated gene in familial Parkinson's disease1 and is also linked to its idiopathic form2. LRRK2 has been proposed to function in membrane trafficking3 and colocalizes with microtubules4. Despi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62fba64898ec938a4c45a66f4add3b5
https://doi.org/10.1038/s41586-020-2673-2
https://doi.org/10.1038/s41586-020-2673-2
Publikováno v:
Microscopy and Microanalysis. 28:1220-1221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a283d8dd8a9f33e6596111f49e2e6234
https://doi.org/10.1017/s1431927622005086
https://doi.org/10.1017/s1431927622005086
Autor:
Charlie J. Hitchman, Jani Reddy Bolla, Carol V. Robinson, Stefan Katharios-Lanwermeyer, George A. O'Toole, Raymond J. Owens, Jan Böhning, Michael R. Wozny, Jiandong Huo, Tanmay A.M. Bharat, Ashleigh N. Morgan, Daniel B. Mihaylov, Charlotte E. Melia, Louis M. Elfari, Patrick C. Hoffmann
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Pseudomonas aeruginosa bacteria form antibiotic-tolerant biofilms that pose significant challenges in clinical settings. Overcoming these challenges requires fundamental insights into how biofilms are formed, combined with innovative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa1f53fd7bf6b9c5d9b7ef7b4fa9bb5
https://doi.org/10.1073/pnas.2109940118
https://doi.org/10.1073/pnas.2109940118