Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Jan Abendroth"'
Autor:
Seyed Mohammad Ghafoori, Gayle F. Petersen, Deborah G. Conrady, Brandy M. Calhoun, Matthew Z. Z. Stigliano, Ruth O. Baydo, Rena Grice, Jan Abendroth, Donald D. Lorimer, Thomas E. Edwards, Jade K. Forwood
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Influenza virus (IV) causes several outbreaks of the flu each year resulting in an economic burden to the healthcare system in the billions of dollars. Several influenza pandemics have occurred during the last century and estimated to have c
Externí odkaz:
https://doaj.org/article/76d2ef5b49eb4543ad2cf4338202406a
Autor:
Aurore Demars, Armelle Vitali, Audrey Comein, Elodie Carlier, Abdulkader Azouz, Stanislas Goriely, Justine Smout, Véronique Flamand, Mégane Van Gysel, Johan Wouters, Jan Abendroth, Thomas E Edwards, Arnaud Machelart, Eik Hoffmann, Priscille Brodin, Xavier De Bolle, Eric Muraille
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009887 (2021)
Brucellosis is one of the most widespread bacterial zoonoses worldwide. Here, our aim was to identify the effector mechanisms controlling the early stages of intranasal infection with Brucella in C57BL/6 mice. During the first 48 hours of infection,
Externí odkaz:
https://doaj.org/article/0ebdeb0dee1242609d7b967c5f88f4d6
Autor:
Logan Tillery, Kayleigh Barrett, Jenna Goldstein, Jared W Lassner, Bram Osterhout, Nathan L Tran, Lily Xu, Ryan M Young, Justin Craig, Ian Chun, David M Dranow, Jan Abendroth, Silvia L Delker, Douglas R Davies, Stephen J Mayclin, Brandy Calhoun, Madison J Bolejack, Bart Staker, Sandhya Subramanian, Isabelle Phan, Donald D Lorimer, Peter J Myler, Thomas E Edwards, Dennis E Kyle, Christopher A Rice, James C Morris, James W Leahy, Roman Manetsch, Lynn K Barrett, Craig L Smith, Wesley C Van Voorhis
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0241738 (2021)
Naegleria fowleri is a pathogenic, thermophilic, free-living amoeba which causes primary amebic meningoencephalitis (PAM). Penetrating the olfactory mucosa, the brain-eating amoeba travels along the olfactory nerves, burrowing through the cribriform
Externí odkaz:
https://doaj.org/article/23d070499b154d11aa93fd5498f6c574
Autor:
Miguel Angel Moreno, Ana Alonso, Pedro Jose Alcolea, Ariel Abramov, Mario García de Lacoba, Jan Abendroth, Sunny Zhang, Thomas Edwards, Don Lorimer, Peter John Myler, Vicente Larraga
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Iss 3, Pp 347-354 (2014)
Leishmania infantum is the etiological agent of zoonotic visceral leishmaniasis in the Mediterranean basin. The disease is fatal without treatment, which has been based on antimonial pentavalents for more than 60 years. Due to resistances, relapses a
Externí odkaz:
https://doaj.org/article/ab9a4aced6e248da8aa7d05948ffb7be
Autor:
Matthew C Clifton, David M Dranow, Alison Leed, Ben Fulroth, James W Fairman, Jan Abendroth, Kateri A Atkins, Ellen Wallace, Dazhong Fan, Guoping Xu, Z J Ni, Doug Daniels, John Van Drie, Guo Wei, Alex B Burgin, Todd R Golub, Brian K Hubbard, Michael H Serrano-Wu
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125010 (2015)
Crystallization of a maltose-binding protein MCL1 fusion has yielded a robust crystallography platform that generated the first apo MCL1 crystal structure, as well as five ligand-bound structures. The ability to obtain fragment-bound structures advan
Externí odkaz:
https://doaj.org/article/1fecc03a2b9c44169e845be5165ab56e
Autor:
Loren Baugh, Larry A Gallagher, Rapatbhorn Patrapuvich, Matthew C Clifton, Anna S Gardberg, Thomas E Edwards, Brianna Armour, Darren W Begley, Shellie H Dieterich, David M Dranow, Jan Abendroth, James W Fairman, David Fox, Bart L Staker, Isabelle Phan, Angela Gillespie, Ryan Choi, Steve Nakazawa-Hewitt, Mary Trang Nguyen, Alberto Napuli, Lynn Barrett, Garry W Buchko, Robin Stacy, Peter J Myler, Lance J Stewart, Colin Manoil, Wesley C Van Voorhis
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53851 (2013)
BACKGROUND:The genus Burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of patients with cancer and cystic fibrosis. Drug resistance has made development of new antimicrobials critical.
Externí odkaz:
https://doaj.org/article/318d4103a02443b8b18e41dab9bdf5d6
Autor:
Thomas E Edwards, Isabelle Phan, Jan Abendroth, Shellie H Dieterich, Amir Masoudi, Wenjin Guo, Stephen N Hewitt, Angela Kelley, David Leibly, Mitch J Brittnacher, Bart L Staker, Samuel I Miller, Wesley C Van Voorhis, Peter J Myler, Lance J Stewart
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Pathogenic bacteria adhere to the host cell surface using a family of outer membrane proteins called Trimeric Autotransporter Adhesins (TAAs). Although TAAs are highly divergent in sequence and domain structure, they are all conceptually comprised of
Externí odkaz:
https://doaj.org/article/872147d5390e4439b21de6e71d990d81
Autor:
Nicholas D. DeBouver, Madison J. Bolejack, Taiwo E. Esan, Damian J. Krysan, Timothy J. Hagen, Jan Abendroth
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 79:137-143
The compound ethyl-adenosyl monophosphate ester (ethyl-AMP) has been shown to effectively inhibit acetyl-CoA synthetase (ACS) enzymes and to facilitate the crystallization of fungal ACS enzymes in various contexts. In this study, the addition of ethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddaf2bcf56d804e8430cfa56c5c44959
https://doi.org/10.1107/s2053230x23003801
https://doi.org/10.1107/s2053230x23003801
Autor:
Martin A. Lowe, Alvaro Cardenas, Jean-Pierre Valentin, Zhaoning Zhu, Jan Abendroth, Jose L. Castro, Reiner Class, Annie Delaunois, Renaud Fleurance, Helga Gerets, Vitalina Gryshkova, Lloyd King, Donald D. Lorimer, Malcolm MacCoss, Julian H. Rowley, Marie-Luce Rosseels, Leandro Royer, Richard D. Taylor, Melanie Wong, Oliver Zaccheo, Vishal P. Chavan, Gokul A. Ghule, Bapusaheb K. Tapkir, Jeremy N. Burrows, Maëlle Duffey, Matthias Rottmann, Sergio Wittlin, Iñigo Angulo-Barturen, María Belén Jiménez-Díaz, Josefine Striepen, Kate J. Fairhurst, Tomas Yeo, David A. Fidock, Alan F. Cowman, Paola Favuzza, Benigno Crespo-Fernandez, Francisco Javier Gamo, Daniel E. Goldberg, Dominique Soldati-Favre, Benoît Laleu, Teresa de Haro
Publikováno v:
Journal of Medicinal Chemistry. 65:14121-14143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec94f8ff9ea22504d996591d0d9a232d
https://doi.org/10.1021/acs.jmedchem.2c01336
https://doi.org/10.1021/acs.jmedchem.2c01336
Autor:
Matthéo Alcaraz, Françoise Roquet-Banères, Stephen Adonai Leon-Icaza, Jan Abendroth, Yves-Marie Boudehen, Céline Cougoule, Thomas E. Edwards, Laurent Kremer
Publikováno v:
ACS Infectious Diseases. 8:2171-2186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::966d2670b6bf268a9c9b21c3a70d808b
https://doi.org/10.1021/acsinfecdis.2c00314
https://doi.org/10.1021/acsinfecdis.2c00314