Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jan A. Ruzicka"'
Publikováno v:
Pathogens, Vol 13, Iss 10, p 829 (2024)
Sequence analysis of the Zaire ebolavirus (EBOV) polymerase (L gene) mRNA, using online tools, identified a highly ranked −1 programmed ribosomal frameshift (FS) signal including an ideal slippery sequence heptamer (UUUAAAA), with an overlapping co
Externí odkaz:
https://doaj.org/article/bf258fb591144e9abd843ed421f98404
Publikováno v:
BBA Advances, Vol 1, Iss , Pp 100023- (2021)
Selenium status plays a major role in health impacts of various RNA viruses. We previously reported potential antisense interactions between viral mRNAs and host mRNAs encoding isoforms of the antioxidant selenoprotein thioredoxin reductase (TXNRD).
Externí odkaz:
https://doaj.org/article/14a541d49f554245a360625c727bfc69
Autor:
Gabrielle P. Dailey, Osama K. Zahid, Komal Sethi, Ethan Will Taylor, Adam R. Hall, Jan A. Ruzicka
Publikováno v:
ACS Nano
The rapid and reliable recognition of nucleic acid sequences is essential to a broad range of fields including genotyping, gene expression analysis, and pathogen screening. For viral detection in particular, the capability is critical for optimal the
Autor:
Jan A. Ruzicka
Publikováno v:
Thrombosis Research
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101632 (2014)
Among the different types of DNA damage that occur endogenously in the cell, depurination is especially prevalent. These lesions can initiate mutagenesis and have been implicated in a variety of diseases, including cancer. Here, we demonstrate a new
Externí odkaz:
https://doaj.org/article/61733b4ebd4948658ba79ab31412aa30
The HIV-1 nef gene terminates in a 3’-UGA stop codon, which is highly conserved in the main group of HIV-1 subtypes, along with a downstream potential coding region that could extend the nef protein by 33 amino acids, if readthrough of the stop cod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae28184ab640e7d2fdbd994d0059120
Publikováno v:
Am J Biopharm Pharm Sci
Objectives: The HIV-1 nef gene terminates in a 3’-UGA stop codon, which is highly conserved in the main group of HIV-1 subtypes, along with a downstream potential coding region that could extend the nef protein by 33 amino acids, if readthrough of
Autor:
Jinsong Zhang, Margaret P. Rayman, Fuming Wang, Jinbao Huang, Weiwei Li, David Stubbs, Yijun Wang, Zhirong Liu, Ethan Will Taylor, Jun He, Xiaochun Wan, Jan A. Ruzicka, Yong Sun
Publikováno v:
Food and Chemical Toxicology
Higher selenium status has been shown to improve the clinical outcome of infections caused by a range of evolutionally diverse viruses, including SARS-CoV-2. However, the impact of SARS-CoV-2 on host-cell selenoproteins remains elusive. The present s
Publikováno v:
Current Topics in Medicinal Chemistry
Regulation of protein expression by non-coding RNAs typically involves effects on mRNA degradation and/or ribosomal translation. The possibility of virus-host mRNA-mRNA antisense tethering interactions (ATI) as a gain-of-function strategy, via the ca
Autor:
Campbell McNicoll, Tim Kemmitt, Rohul H. Adnan, Bruce C. C. Cowie, Faridah Abu Bakar, Christoffer Hoeck, Jan-Yves Ruzicka, Gunther G. Andersson, Vladimir B. Golovko, Gregory F. Metha
Publikováno v:
The Journal of Physical Chemistry C. 119:24465-24474
Well-defined Au–TiO2 materials were synthesized by deposition of triphenylphosphine-protected Au9 clusters on TiO2 (Aeroxide P-25), pre-treated in eight different ways and subsequently exposed to two post-treatments. X-ray photoelectron spectroscop