Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Jan A Stegemann"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Resonant Acoustic Rheometry (RAR), a newly developed ultrasound-based technique for non-contact characterization of soft viscoelastic materials, has shown promise for quantitative viscoelastic assessment of temporally changing soft biomateri
Externí odkaz:
https://doaj.org/article/61a6245514e74fa19d17117b573958ba
Publikováno v:
Cells, Vol 10, Iss 11, p 3123 (2021)
Adipose-derived stem cells (ASCs) are an abundant and easily accessible multipotent stem cell source with potential application in smooth muscle regeneration strategies. In 3D collagen hydrogels, we investigated whether sustained release of growth fa
Externí odkaz:
https://doaj.org/article/04ac1f8d1d3446ceae49ec0940ec0f8a
Autor:
Brandan Walters, Tatiana Uynuk-Ool, Miriam Rothdiener, Julian Palm, Melanie L. Hart, Jan P. Stegemann, Bernd Rolauffs
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Stem cells have been predicted to improve disease outcomes and patient lives. Steering stem cell fate - through controlling cell shape - may substantially accelerate progress towards this goal. As mesenchymal stromal cells (MSCs) are continu
Externí odkaz:
https://doaj.org/article/300e8f51c90a4d3c98cf2320425ab844
Publikováno v:
Biotechnology and Bioengineering. 119:3284-3296
Bioengineered bone designed to heal large defects requires concomitant development of osseous and vascular tissue to ensure engraftment and survival. Adult human mesenchymal stromal cells (MSC) are promising in this application because they have demo
Autor:
Jan P. Stegemann, William R. Wagner, Uta Göbel, Ekaterina Perets, Kam W. Leong, J. Kent Leach, Jeremy Gilbert
Publikováno v:
Journal of Biomedical Materials Research Part A.
Autor:
Chukwuma E. Nweke, Jan P. Stegemann
Publikováno v:
J Biomed Mater Res B Appl Biomater
Biomaterial-based bone regeneration strategies often include a cellular component to accelerate healing. Modular approaches have the potential for minimally-invasive delivery and the ability to conformally fill complex defects. In this study, spheric
Autor:
Weiping Li, Eric C. Hobson, Connor M. Bunch, Joseph B. Miller, Jimmy Nehme, Hau C. Kwaan, Mark M. Walsh, Michael T. McCurdy, John G. Aversa, Anthony V. Thomas, Nuha Zackariya, Samuel J. Thomas, Stephanie A. Smith, Bernard C. Cook, Bryan Boyd, Jan P. Stegemann, Cheri X. Deng
Publikováno v:
Seminars in thrombosis and hemostasis.
Compared with conventional coagulation tests and factor-specific assays, viscoelastic hemostatic assays (VHAs) can provide a more thorough evaluation of clot formation and lysis but have several limitations including clot deformation. In this proof-o
Publikováno v:
Tissue Eng Part B Rev
Inadequate vascularization of engineered tissue constructs is a main challenge in developing a clinically impactful therapy for large, complex, and recalcitrant bone defects. It is well established that bone and blood vessels form concomitantly durin
Publikováno v:
Biomaterials. 295:122050
Autor:
Xiaowei Hong, Andrew J. Putnam, Nicole E. Friend, Ana Y. Rioja, Jan P. Stegemann, Cheri X. Deng, Yen Peng Kong, Julia C. Habif, Jeffrey A. Beamish, Jonathan R. Bezenah
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Revascularization of ischemic tissues is a major barrier to restoring tissue function in many pathologies. Delivery of pro-angiogenic factors has shown some benefit, but it is difficult to recapitulate the complex set of factors required to form stab