C-Nucleosides: Synthetic Strategies and Biological Applications

Autor: Pavel Kočovský, Michal Hocek, Jan Štambaský

Publikováno v: Chemical Reviews. 109:6729-6764

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f6fd185d2924c31c59ed085dd87f77
https://doi.org/10.1021/cr9002165

Preparation of fluorohalomethylmagnesium halides using highly active magnesium metal and their reactions

Autor: Jan Štambaský, Jaroslav Kvíčala, Oldřich Paleta, Martin Skalický

Publikováno v: Journal of Fluorine Chemistry. 126:1390-1395

Highly active magnesium (Rieke magnesium) reacts with fluorohalomethanes at −100 °C forming the corresponding fluorohalomethylmagnesium halides, which undergo nucleophilic substitution with silyl halides or nucleophilic addition with aldehydes or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2593d721c8aafb6ed96860753f35d28
https://doi.org/10.1016/j.jfluchem.2005.07.016

Equilibrium structures of isolated (halogenated) fluorolithiomethanes

Autor: Jaroslav Kvíčala, Jan Štambaský, Oldřich Paleta, Stanislav Böhm

Publikováno v: Journal of Fluorine Chemistry. 113:147-154

Equilibrium structures of isolated fluorolithiomethanes ( 1–3 ), chlorofluorolithiomethanes ( 4 – 6 ), bromofluorolithiomethanes ( 7 – 9 ), and bromochlorofluorolithiomethane ( 10 ) have been calculated at the HF/6-31+G(d,p) and MP2/6-31+G(d,p)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45b98c142e8d7edd47c200aa58937812
https://doi.org/10.1016/s0022-1139(01)00504-8

A modular approach to aryl-C-ribonucleosides via the allylic substitution and ring-closing metathesis sequence. a stereocontrolled synthesis of all four α-/β- and D-/L-C-nucleoside stereoisomers

Autor: Martin Štefko, Jan Štambaský, Ondřej Kysilka, Andrei V. Malkov, Vojtěch Kapras, Pavel Kočovský, Michal Hocek

Publikováno v: The Journal of organic chemistry. 76(19)

Iridium(I)-catalyzed allylation of the enantiopure monoprotected copper(I) alkoxide, generated from (S)-5a, with the enantiopure allylic carbonates (R)-9a,b has been developed as the key step in a new approach to C-nucleoside analogues. The anomeric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e951fe954e7b5239b0f23c7fa09a14e
https://pubmed.ncbi.nlm.nih.gov/21838284

Efficient Synthetic Access to Stable Isotope Labelled Pseudouridine Phosphoramidites for RNA NMR Spectroscopy.

Autor: Glänzer D; Institute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria., Pfeiffer M; Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, NAWI Graz, Petersgasse 12, A-8010, Graz, Austria.; and Austrian Centre of Industrial Biotechnology (acib), Krenngasse 37, A-8010, Graz, Austria., Ribar A; Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, NAWI Graz, Petersgasse 12, A-8010, Graz, Austria.; and Austrian Centre of Industrial Biotechnology (acib), Krenngasse 37, A-8010, Graz, Austria., Zeindl R; Institute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria., Tollinger M; Institute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria., Nidetzky B; Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, NAWI Graz, Petersgasse 12, A-8010, Graz, Austria.; and Austrian Centre of Industrial Biotechnology (acib), Krenngasse 37, A-8010, Graz, Austria., Kreutz C; Institute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Jun 25; Vol. 30 (36), pp. e202401193. Date of Electronic Publication: 2024 May 29.