Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jan‐Willi Janiesch"'
Autor:
Désirée Sauter, Martin Schröter, Christoph Frey, Cornelia Weber, Ulrike Mersdorf, Jan‐Willi Janiesch, Ilia Platzman, Joachim P. Spatz
Publikováno v:
Macromolecular Bioscience
Imitation of cellular processes in cell-like compartments is a current research focus in synthetic biology. Here, a method is introduced for assembling an artificial cytoskeleton in a synthetic cell model system based on a poly(N-isopropyl acrylamide
Autor:
Eli Zamir, Ilia Platzman, Silvia Antona, Christoph Frey, Johannes Patrick Frohnmayer, Joachim P. Spatz, Marian Weiss, Jan-Willi Janiesch
Publikováno v:
Analytical Chemistry
Fluorescence correlation spectroscopy (FCS) is a sensitive technique commonly applied for studying the dynamics of nanoscale-labeled objects in solution. Current analysis of FCS data is largely based on the assumption that the labeled objects are sto
Autor:
Martin Schröter, Dennis Zhang, Joachim P. Spatz, Sebastian Fabritz, Júlia Csatári, Jan-Willi Janiesch, Imre Berger, Oskar Staufer, Silvia Antona, Ilia Platzman
Publikováno v:
Staufer, O, Antona, S, Zhang, D, Csatári, J, Schröter, M, Janiesch, J-W, Fabritz, S, Berger, I, Platzman, I & Spatz, J P 2021, ' Microfluidic production and characterization of biofunctionalized giant unilamellar vesicles for targeted intracellular cargo delivery ', Biomaterials, vol. 264, 120203 . https://doi.org/10.1016/j.biomaterials.2020.120203
Biomaterials
Biomaterials
Lipid-based vesicles have found widespread applications in the life sciences, allowing for fundamental insights into membrane-based processes in cell biology and as carrier systems for drug delivery purposes. So far, mostly small unilamellar vesicles
Autor:
Barbara Haller, Martin Schröter, Jan-Willi Janiesch, Kerstin Göpfrich, Ilia Platzman, Joachim P. Spatz
Publikováno v:
Lab on a Chip
In this manuscript, we introduce a simple, off-the-shelf approach for the on-demand creation of giant unilamellar vesicles (GUVs) or multicompartment synthetic cell model systems in a high-throughput manner. To achieve this, we use microfluidics to e
Autor:
Ilia Platzman, Thomas Surrey, Jonathon Hannabuss, Marian Weiss, Joachim P. Spatz, Gerri Kannenberg, Jan-Willi Janiesch
Publikováno v:
Analytical Chemistry
Water-in-oil emulsion droplets created in droplet-based microfluidic devices have been tested and used recently as well-defined picoliter-sized 3D compartments for various biochemical and biomedical applications. In many of these applications, fluore
Autor:
Kai Sundmacher, Eberhard Bodenschatz, Rumiana Dimova, Joachim P. Spatz, Ilia Platzman, Lucia Theresa Benk, Barbara Haller, Reinhard Lipowsky, Rafael B. Lira, Jan-Willi Janiesch, Jean-Christophe Baret, Thomas Heitkamp, Michael Börsch, Tanja Vidaković-Koch, Johannes Patrick Frohnmayer, Marian Weiss
Publikováno v:
Nature Materials
Nature Materials, Nature Publishing Group, 2017, 17 (1), pp.89-96. ⟨10.1038/nmat5005⟩
Nature Materials, Nature Publishing Group, 2017, 17 (1), pp.89-96. ⟨10.1038/nmat5005⟩
Compartments for the spatially and temporally controlled assembly of biological processes are essential towards cellular life. Synthetic mimics of cellular compartments based on lipid-based protocells lack the mechanical and chemical stability to all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad360b893de0d5eef6e9a7d7e36caf2b
https://hal.archives-ouvertes.fr/hal-01686173
https://hal.archives-ouvertes.fr/hal-01686173
Autor:
Joachim P. Spatz, Kerstin Göpfrich, Kevin Jahnke, Jan-Willi Janiesch, Ilia Platzman, Christoph Frey, Marian Weiss, Silvia Antona
Publikováno v:
Advanced Functional Materials
Droplet‐based microfluidics has emerged as a powerful tool in synthetic biology. For many applications, chemical functionalization of the droplets is a key process. Therefore, a straightforward and broadly applicable approach is developed to functi
Publikováno v:
Journal of the American Chemical Society
Activation, ex vivo expansion of T cells, differentiation into a regulatory subset, and its phenotype-specific high-throughput selection represent major challenges in immunobiology. In part, this is due to the lack of technical means to synthesize su
Publikováno v:
Soft Matter Nanotechnology: From Structure to Function
T-cell interactions with antigen-presenting cells (APCs) are involved in nearly every immunological response in vivo, and consequently activate multiple signaling pathways that, in concert, initiate, drive, and regulate the body's adaptive and innate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398496d5e27d20a4a5ea2ea8ff212465
https://hdl.handle.net/11858/00-001M-0000-002C-C95E-511858/00-001M-0000-0028-2C78-2
https://hdl.handle.net/11858/00-001M-0000-002C-C95E-511858/00-001M-0000-0028-2C78-2
Autor:
Ilia, Platzman, Katarzyna M, Gadomska, Jan-Willi, Janiesch, Ilia, Louban, E Ada, Cavalcanti-Adam, Joachim P, Spatz
Publikováno v:
Methods in cell biology. 119
Engineering of biomimetic interfaces has become a valuable tool for guiding cellular processes such as adhesion, spreading, motility, as well as proliferation, differentiation, and apoptosis. The interaction of cells with the extracellular matrix (EC