Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jan‐Willem E. M. Sels"'
Autor:
Daniek A. M. Meijs, Laure Wynants, Sander M. J. van Kuijk, Clarissa I. E. Scheeren, Anisa Hana, Jannet Mehagnoul-Schipper, Björn Stessel, Margot Vander Laenen, Eline G. M. Cox, Jan-Willem E. M. Sels, Luc J. M. Smits, Johannes Bickenbach, Dieter Mesotten, Iwan C. C. van der Horst, Gernot Marx, Bas C. T. van Bussel, CoDaP Investigators
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Most published prediction models for Coronavirus Disease 2019 (COVID-19) were poorly reported, at high risk of bias, and heterogeneous in model performance. To tackle methodological challenges faced in previous prediction studies, we investi
Externí odkaz:
https://doaj.org/article/0f5fd3711bd64993b62e1801dd81a4b7
Autor:
Jip W. T. M. de Kok, Frank van Rosmalen, Jacqueline Koeze, Frederik Keus, Sander M. J. van Kuijk, José Castela Forte, Ronny M. Schnabel, Rob G. H. Driessen, Thijs T. W. van Herpt, Jan-Willem E. M. Sels, Dennis C. J. J. Bergmans, Chris P. H. Lexis, William P. T. M. van Doorn, Steven J. R. Meex, Minnan Xu, Xavier Borrat, Rachel Cavill, Iwan C. C. van der Horst, Bas C. T. van Bussel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract We validated a Deep Embedded Clustering (DEC) model and its adaptation for integrating mixed datatypes (in this study, numerical and categorical variables). Deep Embedded Clustering (DEC) is a promising technique capable of managing extensiv
Externí odkaz:
https://doaj.org/article/867c03e4fffa4acaa2dd4b72c8bf55da
Autor:
Mark M. G. Mulder, Joep Schellens, Jan-Willem E. M. Sels, Frank van Rosmalen, Anne-Marije Hulshof, Femke de Vries, Ruud Segers, Casper Mihl, Walther N. K. A. van Mook, Aalt Bast, Henri M. H. Spronk, Yvonne M. C. Henskens, Iwan C. C. van der Horst, Hugo ten Cate, Leon J. Schurgers, Marjolein Drent, Bas C. T. van Bussel
Publikováno v:
Journal of Intensive Care, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background Extra-hepatic vitamin K-status, measured by dephosphorylated uncarboxylated matrix Gla protein (dp-ucMGP), maintains vascular health, with high levels reflecting poor vitamin K status. The occurrence of extra-hepatic vitamin K def
Externí odkaz:
https://doaj.org/article/5350234c011e4986b380f9e8c03db898
Autor:
Tom W. van de Berg, Mark M. G. Mulder, Teba Alnima, Magdolna Nagy, Rene van Oerle, Erik A. M. Beckers, Tilman M. Hackeng, Anne-Marije Hulshof, Jan-Willem E. M. Sels, Yvonne M. C. Henskens, Iwan C. C. van der Horst, Hugo ten Cate, Henri M. H. Spronk, Bas C. T. van Bussel, MaastrICCht Collaborators
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCOVID-19 associated coagulopathy (CAC) is associated with an increase in thromboembolic events. Current guidelines recommend prophylactic heparins in the management of CAC. However, the efficacy of this strategy in the intensive care popula
Externí odkaz:
https://doaj.org/article/d4e063b4fb314f20b6c286e5c55e882c
Autor:
Mark M. G. Mulder, LIoyd Brandts, Renée A. G. Brüggemann, Marcel Koelmann, Alexander S. Streng, Renske H. Olie, Hester A. Gietema, Henri M. H. Spronk, Iwan C. C. van der Horst, Jan-Willem E. M. Sels, Joachim E. Wildberger, Sander M. J. van Kuijk, Ronny M. Schnabel, Hugo ten Cate, Yvonne M. C. Henskens, Bas C. T. van Bussel
Publikováno v:
Thrombosis Journal, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background The incidence of pulmonary thromboembolism is high in SARS-CoV-2 patients admitted to the Intensive Care. Elevated biomarkers of coagulation (fibrinogen and D-dimer) and inflammation (c-reactive protein (CRP) and ferritin) are ass
Externí odkaz:
https://doaj.org/article/6bf3e0501f96462e9844fddbefde782c
Autor:
Anne‐Marije Hulshof, Dionne C. W. Braeken, Chahinda Ghossein‐Doha, Susanne van Santen, Jan‐Willem E. M. Sels, Gerhardus J. A. J. M. Kuiper, Iwan C. C. van der Horst, Hugo ten Cate, Bas C. T. vanBussel, Renske H. Olie, Yvonne M. C. Henskens
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 6, Pp n/a-n/a (2021)
Abstract Background The prothrombotic phenotype has been extensively described in patients with acute coronavirus disease 2019 (COVID‐19). However, potential long‐term hemostatic abnormalities are unknown. Objective To evaluate the changes in rou
Externí odkaz:
https://doaj.org/article/08ceed626604492fb610233890d70b47
Autor:
Anne-Marije Hulshof, Renée A. G. Brüggemann, Mark M. G. Mulder, Tom W. van de Berg, Jan-Willem E. M. Sels, Renske H. Olie, Bart Spaetgens, Alexander S. Streng, Paul Verhezen, Iwan C. C. van der Horst, Hugo Ten Cate, Henri M. H. Spronk, Bas C. T van Bussel, Yvonne M. C. Henskens
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Coronavirus Disease 2019 (COVID-19) patients often present with thromboembolic events. In COVID-19 patients, routine hemostatic assays cannot correctly identify patients at risk for thromboembolic events. Viscoelastic testing with rotatio
Externí odkaz:
https://doaj.org/article/3e140dfbe8d149008ae2a5d9ed6d1a51
Autor:
Yvonne M. C. Henskens, Jan-Willem E M Sels, Bas C. T. van Bussel, Magdolna Nagy, Tom Van De Berg, Rene van Oerle, Henri M. H. Spronk, Hugo ten Cate, Anne-Marije Hulshof
Publikováno v:
Thrombosis Research, 201, 84-89. Elsevier Science
Thrombosis Research
Thrombosis Research
INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection is associated with a clear prothrombotic phenotype. Although the exact pathophysiological mechanisms are not yet fully understood, thrombosis is clearly a highly impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e66e54a8d68c68c21d0f6c461857fdd
https://doi.org/10.1016/j.thromres.2021.02.026
https://doi.org/10.1016/j.thromres.2021.02.026
Autor:
Chris P. M. Reutelingsperger, Martine E. Bol, Marcel C. G. van de Poll, Gerry A. F. Nicolaes, Danielle M. H. Beurskens, Tammo Delhaas, Jan-Willem E M Sels
Publikováno v:
Anaesthesia and Intensive Care, 48(3), 221-228. Australian Society of Anaesthetists
Anaesthesia and Intensive Care
Anaesthesia and Intensive Care
Microcirculatory alterations play an important role in the early phase of sepsis. Shedding of the endothelial glycocalyx is regarded as a central pathophysiological mechanism causing microvascular dysfunction, contributing to multiple organ failure a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd354333f7351ebceea189855a3b5076
https://doi.org/10.1177/0310057X20916471
https://doi.org/10.1177/0310057X20916471
Autor:
Ellen J.S. Denessen, Jan-Willem E M Sels, Jos G. Maessen, Iwan C. C. van der Horst, Jean H.T. Daemen, Otto Bekers, Alma M.A. Mingels, Wim H. M. Vroemen, Arnoud W J van 't Hof, Patrique Segers, Samuel Heuts
Publikováno v:
American Journal of Cardiology, 163, 25-31. Excerpta Medica, Elsevier Science
Various definitions of myocardial infarction type 5 after coronary artery bypass grafting (CABG) have been proposed (myocardial infarction [MI-5], also known as peri-procedural MI), using different biomarkers and different and arbitrary cut-off value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcad7bb273d439408d449ae46a6b0620
https://pubmed.ncbi.nlm.nih.gov/34763830
https://pubmed.ncbi.nlm.nih.gov/34763830