Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jan‐Marcus Seifert"'
Autor:
Sabine Nakowitsch, Christiane Koller, Jan-Marcus Seifert, Marielle König-Schuster, Nicole Unger-Manhart, Cornelia Siegl, Norman Kirchoff, Elisabeth Foglar, Christine Graf, Martina Morokutti-Kurz, Marianne Neurath, Svenja Sladek, Christian Knecht, Wolfgang Sipos, Eva Prieschl-Grassauer, Andreas Grassauer
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 847 (2020)
Due to fast nasal mucociliary clearance, only the dissolved drug content can effectively permeate the mucosa and be pharmaceutically active after intranasal application of suspensions. Therefore, the aim of this study was to increase the budesonide c
Externí odkaz:
https://doaj.org/article/f4b3eab3baa741a3ab8edd0179a444ed
Autor:
Alexandra Hebar, Christiane Koller, Jan-Marcus Seifert, Monika Chabicovsky, Angelika Bodenteich, Andreas Bernkop-Schnürch, Andreas Grassauer, Eva Prieschl-Grassauer
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122911 (2015)
Carrageenan has been widely used as food additive for decades and therefore, an extended oral data set is available in the public domain. Less data are available for other routes of administration, especially intranasal administration. The current pu
Externí odkaz:
https://doaj.org/article/db3ca29dfd7e43558ebd00c137d2fa53
Autor:
Martina Morokutti-Kurz, Marielle König-Schuster, Christiane Koller, Christine Graf, Philipp Graf, Norman Kirchoff, Benjamin Reutterer, Jan-Marcus Seifert, Hermann Unger, Andreas Grassauer, Eva Prieschl-Grassauer, Sabine Nakowitsch
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128794 (2015)
Carrageenan is a clinically proven and marketed compound for the treatment of viral upper respiratory tract infections. As infections caused by influenza virus are often accompanied by infections with other respiratory viruses the combination of a sp
Externí odkaz:
https://doaj.org/article/53c29c16074c4287bf2fbd5f33f20f5a
Autor:
Cornelia Siegl, Sabine Nakowitsch, Nicole Unger-Manhart, Christine Graf, Norman Kirchoff, Jan-Marcus Seifert, Martina Morokutti-Kurz, Marianne Neurath, Christian Knecht, Svenja Sladek, Eva Prieschl-Grassauer, Marielle König-Schuster, Christiane Koller, Andreas Grassauer, Wolfgang Sipos, Elisabeth Foglar
Publikováno v:
Pharmaceutics, Vol 12, Iss 847, p 847 (2020)
Pharmaceutics
Volume 12
Issue 9
Pharmaceutics
Volume 12
Issue 9
Due to fast nasal mucociliary clearance, only the dissolved drug content can effectively permeate the mucosa and be pharmaceutically active after intranasal application of suspensions. Therefore, the aim of this study was to increase the budesonide c
Publikováno v:
Journal of Combinatorial Chemistry. 12:647-654
On-bead screening of one-bead one compound (OBOC) libraries is an ultra fast surface based primary high-throughput screening (HTS) method. Typically the binding of a tagged target protein to bead immobilized compounds or its altered enzymatic activit
Autor:
Thierry Kimmerlin, Manfred Auer, Volker Uhl, Roman Bauer, Martin Hintersteiner, Nicole-Claudia Meisner, Geraldine Garavel, Thorsten Schindler, Jan-Marcus Seifert
Publikováno v:
ChemBioChem. 10:994-998
New and improved: The incorporation of a 6-chlorotryptophan (6-Cl-Trp) into a beta-peptide (M)-3(14) helix leads to a high-affinity hDM2 inhibitor, as demonstrated by fluorescence fluctuation analysis at single molecule resolution. When conjugated to
Autor:
Michaela Lang, Volker Uhl, Nicole-Claudia Meisner, Jan-Marcus Seifert, Roger Benoit, Armin Widmer, Hubert Gstach, Manfred Auer, Roman Bauer, Martin Hintersteiner, Torsten Schindler
Publikováno v:
Journal of Molecular Biology. 386:435-450
Posttranscriptional regulation and RNA metabolism have become central topics in the understanding of mammalian gene expression and cell signalling, with the 3' untranslated region emerging as the coordinating unit. The 3' untranslated region trans-ac
Autor:
Maximilian Woisetschlaeger, Kurt Mueller, Roman Bauer, Lukas Oberer, Johannes Ottl, Nathalie Harrer, Jan-Marcus Seifert, Volker Uhl, Christian Guenat, Martin Hintersteiner, Manfred Auer, Christof Buehler, Serge Moss, Nicole-Claudia Meisner, Hans-Ulrich Naegeli
Publikováno v:
Nature Chemical Biology. 3:508-515
Careful regulation of mRNA half-lives is a fundamental mechanism allowing cells to quickly respond to changing environmental conditions. The mRNA-binding Hu proteins are important for stabilization of short-lived mRNAs. Here we describe the identific
Autor:
Andreas Bernkop-Schnürch, Angelika Bodenteich, Alexandra Hebar, Jan-Marcus Seifert, Monika Chabicovsky, Andreas Grassauer, Eva Prieschl-Grassauer, Christiane Koller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0122911 (2015)
PLoS ONE, Vol 10, Iss 4, p e0122911 (2015)
Carrageenan has been widely used as food additive for decades and therefore, an extended oral data set is available in the public domain. Less data are available for other routes of administration, especially intranasal administration. The current pu
Autor:
Christine Graf, Jan-Marcus Seifert, Norman Kirchoff, Martina Morokutti-Kurz, Philipp Graf, Andreas Grassauer, Benjamin Reutterer, Eva Prieschl-Grassauer, Hermann Unger, Sabine Nakowitsch, Christiane Koller, Marielle König-Schuster
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128794 (2015)
PLoS ONE
PLOS ONE
PLoS ONE
PLOS ONE
Background Carrageenan is a clinically proven and marketed compound for the treatment of viral upper respiratory tract infections. As infections caused by influenza virus are often accompanied by infections with other respiratory viruses the combinat