Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jan, Zaloga"'
Autor:
Maizlinda I. Idris, Jan Zaloga, Rainer Detsch, Judith A. Roether, Harald Unterweger, Christoph Alexiou, Aldo R. Boccaccini
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Surface modification of superparamagnetic iron oxide nanoparticles (SPIONs) has been introduced with lauric acid and oleic acid via co-precipitation and thermal decomposition methods, respectively. This modification is required to increase t
Externí odkaz:
https://doaj.org/article/3c427aa4008e43e18f10247c3542e084
Autor:
Marina Pöttler, Andreas Staicu, Jan Zaloga, Harald Unterweger, Bianca Weigel, Eveline Schreiber, Simone Hofmann, Irmi Wiest, Udo Jeschke, Christoph Alexiou, Christina Janko
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 26280-26290 (2015)
Nanoparticles that are aimed at targeting cancer cells, but sparing healthy tissue provide an attractive platform of implementation for hyperthermia or as carriers of chemotherapeutics. According to the literature, diverse effects of nanoparticles re
Externí odkaz:
https://doaj.org/article/10c628eb2d894b6a90a5d2895d7c7e59
Autor:
Annkathrin Hornung, Marina Poettler, Ralf P. Friedrich, Jan Zaloga, Harald Unterweger, Stefan Lyer, Johannes Nowak, Stefan Odenbach, Christoph Alexiou, Christina Janko
Publikováno v:
Molecules, Vol 20, Iss 10, Pp 18016-18030 (2015)
Major problems of cancer treatment using systemic chemotherapy are severe side effects. Magnetic drug targeting (MDT) employing superparamagnetic iron oxide nanoparticles (SPION) loaded with chemotherapeutic agents may overcome this dilemma by increa
Externí odkaz:
https://doaj.org/article/8ba085889bce49348ea47033ed24a38f
Autor:
Jan Zaloga, Marcus Stapf, Johannes Nowak, Marina Pöttler, Ralf P. Friedrich, Rainer Tietze, Stefan Lyer, Geoffrey Lee, Stefan Odenbach, Ingrid Hilger, Christoph Alexiou
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 8, Pp 19291-19307 (2015)
Superparamagnetic iron oxide nanoparticles (SPIONs) are frequently used for drug targeting, hyperthermia and other biomedical purposes. Recently, we have reported the synthesis of lauric acid-/albumin-coated iron oxide nanoparticles SEONLA-BSA, which
Externí odkaz:
https://doaj.org/article/bd845f2e7def4bb987e4f20969023be4
Autor:
Jan Zaloga, Christina Janko, Rohit Agarwal, Johannes Nowak, Robert Müller, Aldo R. Boccaccini, Geoffrey Lee, Stefan Odenbach, Stefan Lyer, Christoph Alexiou
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 9368-9384 (2015)
Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted increasing attention in many biomedical fields. In magnetic drug targeting SPIONs are injected into a tumour supplying artery and accumulated inside the tumour with a magnet. The effe
Externí odkaz:
https://doaj.org/article/9d7d3799d8ca40fc8cde64176ece39a7
Autor:
Artem Feoktystov, Jan Zaloga, Thomas Brückel, Vasil M. Garamus, Christoph Alexiou, Rainer Tietze, Weronika Karawacka, Stefan Lyer, Alexander Ioffe
Publikováno v:
Colloids and surfaces / B 161, 18-26 (2018). doi:10.1016/j.colsurfb.2017.09.057
Colloids and Surfaces B: Biointerfaces
Zaloga, J.; Feoktystov, A.; Haramus, V.M.; Karawacka, W.; Loffe, A.; Brueckel, T.; Tietze, R.; Alexiou, C.; Lyer, S.: Studies on the adsorption and desorption of mitoxantrone to lauric acid/albumin coated iron oxide nanoparticles. In: Colloids and Surfaces B. Vol. 161 (2018) 18-26. (DOI: /10.1016/j.colsurfb.2017.09.057)
Colloids and Surfaces B: Biointerfaces
Zaloga, J.; Feoktystov, A.; Haramus, V.M.; Karawacka, W.; Loffe, A.; Brueckel, T.; Tietze, R.; Alexiou, C.; Lyer, S.: Studies on the adsorption and desorption of mitoxantrone to lauric acid/albumin coated iron oxide nanoparticles. In: Colloids and Surfaces B. Vol. 161 (2018) 18-26. (DOI: /10.1016/j.colsurfb.2017.09.057)
A rational use of superparamagnetic iron oxide nanoparticles (SPIONs) in drug delivery, diagnostics, and other biomedical applications requires deep understanding of the molecular drug adsorption/desorption mechanisms for proper design of new pharmac
Autor:
Rainer Tietze, Marina Pöttler, Stefan Lyer, Christoph Alexiou, Christina Janko, Dietmar Eberbeck, Stephan Dürr, Jan Zaloga
Publikováno v:
Journal of Magnetism and Magnetic Materials. 431:281-284
Various nanoparticle systems have been developed for medical applications in recent years. For constant improvement of efficacy and safety of nanoparticles, a close interdisciplinary interplay between synthesis, physicochemical characterizations and
Pharmaceutical formulation of HSA hybrid coated iron oxide nanoparticles for magnetic drug targeting
Autor:
Geoffrey Lee, Ralph Heimke-Brinck, Marina Pöttler, Harald Mangge, Jan Zaloga, Frank Dörje, Christoph Alexiou, Rainer Tietze, Eva Baum, Stefan Lyer, Ralf P Friedrich, Gerd Leitinger, Gunter Almer
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 101:152-162
In this work we present a new formulation of superparamagnetic iron oxide nanoparticles (SPIONs) for magnetic drug targeting. The particles were reproducibly synthesized from current good manufacturing practice (cGMP) - grade substances. They were su
Autor:
Harald Unterweger, Jan Zaloga, Marina Pöttler, Stefan Lyer, Ralf P Friedrich, Rainer Tietze, Christoph Alexiou, Christina Janko, Stephan Dürr
Publikováno v:
Biochemical and Biophysical Research Communications. 468:463-470
Nanoparticles have belonged to various fields of biomedical research for quite some time. A promising site-directed application in the field of nanomedicine is drug targeting using magnetic nanoparticles which are directed at the target tissue by mea
Autor:
Christoph Alexiou, Jan Zaloga, Iwona Cicha, Stefan Lyer, Harald Unterweger, Marina Poettler, Rainer Tietze, Ralf P Friedrich, Christina Janko, Stephan Duerr, Jasmin Matuszak, Raminder Singh
Publikováno v:
Nanomedicine. 10:3287-3304
Nanomedicine offers tremendous opportunities for the development of novel therapeutic and diagnostic tools. During the last decades, extensive knowledge was gained about stabilizing and the coating of nanoparticles, their functionalization for drug b