Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Jan, Vondráček"'
Autor:
Tereza Smutná, Jana Dumková, Daniela Kristeková, Markéta Laštovičková, Adriena Jedličková, Lucie Vrlíková, Bohumil Dočekal, Lukáš Alexa, Hana Kotasová, Vendula Pelková, Zbyněk Večeřa, Kamil Křůmal, Jiří Petráš, Pavel Coufalík, Dalibor Všianský, Samuel Záchej, Dominik Pinkas, Jan Vondráček, Aleš Hampl, Pavel Mikuška, Marcela Buchtová
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-28 (2022)
Abstract Background Inhalation of lead oxide nanoparticles (PbO NPs), which are emitted to the environment by high-temperature technological processes, heavily impairs target organs. These nanoparticles pass through the lung barrier and are distribut
Externí odkaz:
https://doaj.org/article/a358cefb521242e29da92c9c03770d3b
Autor:
Jan Vondráček
Publikováno v:
Zeitschrift für Ostmitteleuropa-Forschung, Vol 70, Iss 3, Pp 439-465 (2021)
Externí odkaz:
https://doaj.org/article/4da1f6f28cb646c9a22426ba0ea6ed1e
Autor:
Gerardo Vázquez-Gómez, Martina Karasová, Zuzana Tylichová, Markéta Kabátková, Aleš Hampl, Jason Matthews, Jiří Neča, Miroslav Ciganek, Miroslav Machala, Jan Vondráček
Publikováno v:
Cells, Vol 11, Iss 4, p 707 (2022)
Apart from its role in the metabolism of carcinogens, the aryl hydrocarbon receptor (AhR) has been suggested to be involved in the control of inflammatory responses within the respiratory tract. However, the mechanisms responsible for this are only p
Externí odkaz:
https://doaj.org/article/aecd33d6caf949ad865d7b0f561df282
Autor:
Jiřina Hofmanová, Josef Slavík, Petra Ovesná, Zuzana Tylichová, Ladislav Dušek, Nicol Straková, Alena Hyršlová Vaculová, Miroslav Ciganek, Zdeněk Kala, Miroslav Jíra, Igor Penka, Jitka Kyclová, Zdeněk Kolář, Alois Kozubík, Miroslav Machala, Jan Vondráček
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228010 (2020)
Identification of changes of phospholipid (PL) composition occurring during colorectal cancer (CRC) development may help us to better understand their roles in CRC cells. Here, we used LC-MS/MS-based PL profiling of cell lines derived from normal col
Externí odkaz:
https://doaj.org/article/d3d02b79a03c480989e24cf94b55ad2e
Autor:
Miroslav Machala, Josef Slavík, Ondrej Kováč, Jiřina Procházková, Kateřina Pěnčíková, Martina Pařenicová, Nicol Straková, Jan Kotouček, Pavel Kulich, Steen Mollerup, Jan Vondráček, Martina Hýžďalová
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9195 (2021)
Sphingolipids (SLs), glycosphingolipids (GSLs), and eicosanoids are bioactive lipids, which play important roles in the etiology of various diseases, including cancer. However, their content and roles in cancer cells, and in particular in the exosome
Externí odkaz:
https://doaj.org/article/2df22ff600314f07a1040b168baf3e9e
Autor:
Jiřina Hofmanová, Josef Slavík, Miroslav Ciganek, Petra Ovesná, Zuzana Tylichová, Martina Karasová, Ondřej Zapletal, Nicol Straková, Jiřina Procházková, Jan Bouchal, Zdeněk Kolář, Jiří Ehrmann, Monika Levková, Zlatka Hušková, Pavel Skalický, Alois Kozubík, Miroslav Machala, Jan Vondráček
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6650 (2021)
The development of colon cancer, one of the most common malignancies, is accompanied with numerous lipid alterations. However, analyses of whole tumor samples may not always provide an accurate description of specific changes occurring directly in tu
Externí odkaz:
https://doaj.org/article/d72a2e38df374328a61dd8cc467d11d4
Autor:
Ondřej Slabý, Kateřina Nevědělová, Igor Kiss, Veronika Zubáňová, Zdeněk Kala, Zuzana Tylichová, Jana Nekvindová, Jan Vondráček, Alena Hyršlová Vaculová, Lucia Bohovicova, Pavel Fabian, Martin Krkoška, Petr Kysela, Jarmila Herůdková, Lenka Ostřížková, Vladimir Palicka, Lenka Radová
Publikováno v:
Pharmacological Reports. 74:148-158
Background Hepatocellular carcinoma (HCC) is a major contributor to the worldwide cancer burden. Recent studies on HCC have demonstrated dramatic alterations in expression of several cytochrome P450 (CYP) family members that play a crucial role in bi
Autor:
Barbora Vyhlídalová, Kristýna Krasulová, Petra Pečinková, Adéla Marcalíková, Radim Vrzal, Lenka Zemánková, Jan Vančo, Zdeněk Trávníček, Jan Vondráček, Martina Karasová, Sridhar Mani, Zdeněk Dvořák
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2614 (2020)
We examined the effects of gut microbial catabolites of tryptophan on the aryl hydrocarbon receptor (AhR). Using a reporter gene assay, we show that all studied catabolites are low-potency agonists of human AhR. The efficacy of catabolites differed s
Externí odkaz:
https://doaj.org/article/04270e0b74804ce4a71a903df1898c26
Autor:
Jan Vondráček
Publikováno v:
Current Drug Metabolism. 22:584-595
Autor:
Soňa Marvanová, Kateřina Pěnčíková, Lenka Pálková, Miroslav Ciganek, Jiří Petráš, Anna Lněničková, Jan Vondráček, Miroslav Machala
Publikováno v:
Science of The Total Environment. 879:162924