Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jan, Schejbal"'
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0a8293aa666dfe4bfe51618b4e69bbe
https://doi.org/10.1007/s11095-023-03510-3
https://doi.org/10.1007/s11095-023-03510-3
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6199c861b94fab89194d7d6636453020
https://doi.org/10.1007/s11095-023-03490-4
https://doi.org/10.1007/s11095-023-03490-4
Publikováno v:
J Proteome Res
In-depth LC–MS-based proteomic profiling of limited biological and clinical samples, such as rare cells or tissue sections from laser capture microdissection or microneedle biopsies, has been problematic due, in large, to the inefficiency of sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0948757639ed7406499695aa1f22d0d2
https://doi.org/10.1021/acs.jproteome.0c00890
https://doi.org/10.1021/acs.jproteome.0c00890
Publikováno v:
Journal of Chromatography A. 1487:235-241
In this work a novel capillary electrophoresis-mass spectrometry (CE-MS) based method was developed and validated for the assay of β-secretase (BACE1) activity as a potential target for Alzheimer's disease (AD) treatment. In contrast with the typica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fab08cf4278fc78569a62e47889fb2e
https://doi.org/10.1016/j.chroma.2017.01.057
https://doi.org/10.1016/j.chroma.2017.01.057
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2089
Alzheimer's disease is the most common cause of dementia, currently afflicting almost 40 million patients worldwide. According to the amyloid cascade hypothesis, the pathogenesis of the disease could be slowed down or even stopped by the inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d34c3c6dfa043ee1ba445252dfe45c6
https://pubmed.ncbi.nlm.nih.gov/31773652
https://pubmed.ncbi.nlm.nih.gov/31773652
Publikováno v:
Methods in Molecular Biology ISBN: 9781071601624
Alzheimer's disease is the most common cause of dementia, currently afflicting almost 40 million patients worldwide. According to the amyloid cascade hypothesis, the pathogenesis of the disease could be slowed down or even stopped by the inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd7301d450857231c7b0965415170d3f
https://doi.org/10.1007/978-1-0716-0163-1_9
https://doi.org/10.1007/978-1-0716-0163-1_9
Publikováno v:
Journal of separation science. 42(5)
Capillary electrophoresis integrated immobilized enzyme reactors are becoming an increasingly popular alternative for enzyme kinetic and inhibition assays thanks to their unique set of features including cost effectiveness, repeated use of the enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cb1ad8a08029614ec61c9b7d4391eb
https://pubmed.ncbi.nlm.nih.gov/30663871
https://pubmed.ncbi.nlm.nih.gov/30663871
Publikováno v:
Analytical and bioanalytical chemistry. 410(28)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI TOF MS) is a well-established method with a unique set of qualities including sensitivity, minute sample consumption, and label-free detection, all of which are highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ba8d93dff96f48c6e81eee1774886a
https://pubmed.ncbi.nlm.nih.gov/30218128
https://pubmed.ncbi.nlm.nih.gov/30218128
Autor:
Pranov Ramana, Patrick Augustijns, Jan Schejbal, Zdenĕk Glatz, Ann Van Schepdael, Johan A. Martens, Erwin Adams, Kristof Houthoofd
Publikováno v:
Electrophoresis. 39(7)
In this paper, we demonstrate the effectiveness of a new 3D printed magnet holder that enables capture of magnetic microparticles in commercially available capillary electrophoresis equipment with a liquid or air based coolant system. The design as w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28e0bdcd60cd2945fadf61c2772ddd9
https://pubmed.ncbi.nlm.nih.gov/29315710
https://pubmed.ncbi.nlm.nih.gov/29315710
Autor:
Zdeněk Glatz, Jan Schejbal
Publikováno v:
Journal of separation science. 41(1)
Enzymes play an essential role in many aspects of pharmaceutical research as drug targets, drug metabolizers, enzyme drugs and more. In this specific field, enzyme assays are required to meet a number of specific requirements, such as low cost, easy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f5a93114420124da4d34580471d26a
https://pubmed.ncbi.nlm.nih.gov/28988452
https://pubmed.ncbi.nlm.nih.gov/28988452