Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Jan, Mous"'
Autor:
Danijela Tatovic, James Caradoc Birchall, Colin M. Dayan, Jan Mous, Florence Susan Wong, Sion Coulman, Maria Dul, Yotam Levin, Martina A. McAteer, Mark Peakman, Efrat Kochba, Bart O. Roep, P Williams, M. Stefanidou, T Nikolic
Publikováno v:
International Journal of Pharmaceutics. 562:303-312
Antigen specific immunotherapy aims to tolerise patients to specific autoantigens that are responsible for the pathology of an autoimmune disease. Immune tolerance is generated in conditions where the immune response is suppressed and thus gold nanop
Using gold nanoparticles for enhanced intradermal delivery of poorly soluble auto-antigenic peptides
Autor:
Bernard Malissen, Martina A. McAteer, James Caradoc Birchall, Colin M. Dayan, Yotam Levin, F. Susan Wong, Sandrine Henri, Joanne Davies, Efrat Kochba, Ravinder K. Singh, Jan Mous, Camille Malosse, Sion Coulman
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine
Nanomedicine: Nanotechnology, Biology and Medicine, 2020, ⟨10.1016/j.nano.2020.102321⟩
Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2020, ⟨10.1016/j.nano.2020.102321⟩
Nanomedicine: Nanotechnology, Biology and Medicine, 2020, ⟨10.1016/j.nano.2020.102321⟩
Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2020, ⟨10.1016/j.nano.2020.102321⟩
International audience; Ultra-small 1-2 nm gold nanoparticles (NP) were conjugated with a poorly-soluble peptide auto-antigen, associated with type 1 diabetes, to modify the peptide pharmacokinetics, following its intradermal delivery. Peptide distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33db1447d49f7807136dd9ea409af277
https://orca.cardiff.ac.uk/id/eprint/136850/1/Using+gold+nanoparticles+for+enhanced+intradermal+delivery+of+poorly+soluble+auto-antigenic+peptides+.pdf
https://orca.cardiff.ac.uk/id/eprint/136850/1/Using+gold+nanoparticles+for+enhanced+intradermal+delivery+of+poorly+soluble+auto-antigenic+peptides+.pdf
Autor:
Jan Mous, Craig Cook, Colin M. Dayan, Bernard Malissen, Susan Wong, Sandrine Henri, Efrat Kochba, Sian Coulman, James Caradoc Birchall, Johnny Ludvigsson, Tatjana Nikolic, Yotam Levin, Bart O. Roep, Martina Duric, Rosaura Casas, Mark Peakman
Publikováno v:
Impact. 2017:6-8
Autor:
David Brady, Jan Mous
Publikováno v:
Personalized medicine. 2(1)
IntegraGen SA is at the stage of commercializing a series of innovative IntegraTests™ to position itself as a leader within the rapidly growing market of predictive medicine. By applying its proprietary gene-mapping technology GenomeHIP™ (Genome
Autor:
Gian C. Winkler, Jan Mous, Clive C. Kuenzle, Claus W. Heizmann, Göpf Morgenegg, Ulrich Hübscher
Publikováno v:
Journal of Neurochemistry. 47:54-62
A single-stranded DNA-binding protein of Mr 35,000 (35K protein) was isolated from calf cerebral cortex by affinity chromatography on immobilized double-stranded and single-stranded DNA. Its localization in the nuclear compartment was demonstrated by
Publikováno v:
European Journal of Biochemistry. 115:115-121
The amino acid sequence of the glycosylated component C3 of rat prostatic binding protein has been determined. The peptides obtained by digestion of the S-carboxamidomethylated or S-aminoethylated glycoprotein with trypsin and Staphylococcus aureus p
Autor:
Georg Casari, Carmen Kaiser, H. Voss, Zaccharias Cheruvallath, Bernhard Haubold, Michael Hoefer, Jan Mous, Harald Kranz, Michael Albers, Manfred Koegl, David A. Jackson, Svante Pääbo, Kerstin Otte, Paul Thompson, Claus Kremoser, Ingo Kober, Ulrich Deuschle, Bettina Remmel
Publikováno v:
Molecular and Cellular Biology. 23:864-872
Nuclear receptors are ligand-modulated transcription factors. On the basis of the completed human genome sequence, this family was thought to contain 48 functional members. However, by mining human and mouse genomic sequences, we identified FXRbeta a
Autor:
Helmut Jacobsen, Ludwina Ahlborn-Laake, Ralf Bartenschlager, Pascal Bouffard, Noel Roberts, Jan Mous
Publikováno v:
Virology. 209(1):52-59
Hepatitis C virus (HCV) encodes a polyprotein of which the majority of nonstructural proteins are matured by the viral serine proteinase located in the N terminus of NS3. Intracellular studies using recombinant vaccinia virus have shown that both NS3
Autor:
Jan Mous, Kaya Yasargil, Helmut Jacobsen, Dean L. Winslow, Ian B. Duncan, J. Charles Craig, Anthony Kröhn
Publikováno v:
Virology. 206:527-534
A human immunodeficiency virus type 1 (HIV-1) variant with highly reduced susceptibility to Ro 31-8959, an inhibitor of the viral proteinase, has been selected by repeated passage of wild-type virus in CEM cells in the presence of increasing concentr
Publikováno v:
Journal of Virology. 68:5045-5055
Recombinant vaccinia viruses were used to study the processing of hepatitis C virus (HCV) nonstructural polyprotein precursor. HCV-specific proteins and cleavage products were identified by size and by immunoprecipitation with region-specific antiser