Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Jan, Martinek"'
Autor:
Victor G. Wang, Zichao Liu, Jan Martinek, Ali Foroughi pour, Jie Zhou, Hannah Boruchov, Kelly Ray, Karolina Palucka, Jeffrey H. Chuang
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract The tumor microenvironment (TME) and the cellular interactions within it can be critical to tumor progression and treatment response. Although technologies to generate multiplex images of the TME are advancing, the many ways in which TME ima
Externí odkaz:
https://doaj.org/article/1f4280d59b514f9a94da98669d1d6645
Autor:
Diana Cadena Castaneda, Sonia Jangra, Marina Yurieva, Jan Martinek, Megan Callender, Matthew Coxe, Angela Choi, Juan García-Bernalt Diego, Te-Chia Wu, Florentina Marches, Damien Chaussabel, Adolfo García-Sastre, Michael Schotsaert, Adam Williams, Karolina Palucka
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102735- (2023)
Summary: Primary human lung organoid-derived air-liquid interface (ALI) cultures serve as a physiologically relevant model to study human airway epithelium in vitro. Here, we present a protocol for establishing these cultures from cryopreserved human
Externí odkaz:
https://doaj.org/article/b465519e6c2441c6bdb976ce7b5806cd
Autor:
Miroslav Valtr, Petr Klapetek, Jan Martinek, Ondřej Novotný, Zdeněk Jelínek, Václav Hortvík, David Nečas
Publikováno v:
HardwareX, Vol 15, Iss , Pp e00451- (2023)
A low-cost Digital Signal Processor (DSP) unit for advanced Scanning Probe Microscopy measurements is presented. It is based on Red Pitaya board and custom built electronic boards with additional high bit depth AD and DA converters. By providing all
Externí odkaz:
https://doaj.org/article/38f653f90be043c5b1805757311d04a4
Autor:
Erica Bellinvia, Judith García-González, Petra Cifrová, Jan Martinek, Lenka Sikorová, Lenka Havelková, Kateřina Schwarzerová
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Protein complex Arp2/3 has a conserved role in the nucleation of branched actin filaments. It is constituted of seven subunits, including actin-like subunits ARP2 and ARP3 plus five other subunits called Arp2/3 Complex Component 1 to 5, whic
Externí odkaz:
https://doaj.org/article/765cd075a84543de8d3c372bdace9b3c
Autor:
Diana Cadena Castaneda, Sonia Jangra, Marina Yurieva, Jan Martinek, Megan Callender, Matthew Coxe, Angela Choi, Juan García-Bernalt Diego, Jianan Lin, Te-Chia Wu, Florentina Marches, Damien Chaussabel, Peter Yu, Andrew Salner, Gabrielle Aucello, Jonathan Koff, Briana Hudson, Sarah E. Church, Kara Gorman, Esperanza Anguiano, Adolfo García-Sastre, Adam Williams, Michael Schotsaert, Karolina Palucka
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107374- (2023)
Summary: The COVID-19 pandemic continues to be a health crisis with major unmet medical needs. The early responses from airway epithelial cells, the first target of the virus regulating the progression toward severe disease, are not fully understood.
Externí odkaz:
https://doaj.org/article/b51b64e50b72469895f79ce437b3fedc
Autor:
Jan Martinek, Ryan C Fields, Scott Gettinger, Karolina Palucka, Katerina Politi, Jun Zhao, Ye Bi, Richard A Flavell, Frank Detterbeck, Obi Griffith, Liang Shan, Malachi Griffith, Michael Chiorazzi, Bradley Krasnick, Yunjiang Zheng, Keenan J Robbins, Rihao Qu, Gabriel Kaufmann, Zachary Skidmore, Melani Juric, Laura A Henze, Frederic Brösecke, Adam Adonyi, Esen Sefik, Jacqueline Mudd, S Peter Goedegebuure, Abimbola Oyedeji, Sofia Fertuzinhos, Rolando Garcia-Milian, Daniel Boffa, Andrew Dhanasopon, Justin Blasberg, Benjamin Judson, Yuval Kluger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 7 (2023)
Background Interactions between immune and tumor cells are critical to determining cancer progression and response. In addition, preclinical prediction of immune-related drug efficacy is limited by interspecies differences between human and mouse, as
Externí odkaz:
https://doaj.org/article/9479165cf09946f8937b35f6027d8425
Autor:
Nirav Thakkar, Astrid Giesecke, Olga Bazalova, Jan Martinek, Vlastimil Smykal, Ralf Stanewsky, David Dolezel
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Circadian clocks are timing devices that rhythmically adjust organism’s behavior, physiology, and metabolism to the 24-h day-night cycle. Eukaryotic circadian clocks rely on several interlocked transcription-translation feedback loops, where protei
Externí odkaz:
https://doaj.org/article/8a08bfcbb27c42fe98d026f0c0e00e00
Autor:
Jan Martinek, Te-Chia Wu, Lili Sun, Jianan Lin, Kyung In Kim, Florentina Marches, Paul Robson, Joshy George, Karolina Palucka
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101698- (2022)
Summary: We describe a pipeline for optimized and streamlined multiplexed immunofluorescence-guided laser capture microdissection allowing the harvest of individual cells based on their phenotype and tissue localization for transcriptomic analysis wi
Externí odkaz:
https://doaj.org/article/77f275be7d9f486db7fcb7f4f44effee
Autor:
Erica Bellinvia, Judith García‑González, Petra Cifrová, Jan Martinek, Lenka Sikorová, Lenka Havelková, Kateřina Schwarzerová
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/1434f05ea0ef41c986eabfb0e6d135e0
Autor:
Alexandra Lochmanová, Jan Martinek, Hana Tomášková, Hana Zelená, Kersten Dieckmann, Evelin Grage-Griebenow, Eduard Ježo, Jaroslav Janošek
Publikováno v:
Diagnostics, Vol 13, Iss 4, p 637 (2023)
Cellular immunity against SARS-CoV-2 is an important component of the immune response to the virus. At present, two such tests based on interferon-gamma release (interferon-γ release assays, IGRAs) are available—Quan-T-Cell SARS-CoV-2 by EUROIMMUN
Externí odkaz:
https://doaj.org/article/205415d776744c0ea4f185892153acdc