Negative symptoms and social cognition as mediators of the relationship between neurocognition and functional outcome in schizophrenia

Autor: Giulia M. Giordano, Pasquale Pezzella, Armida Mucci, Stephen F. Austin, Andreas Erfurth, Birte Glenthøj, Alex Hofer, Jan Hubenak, Jan Libiger, Ingrid Melle, Mette Ø. Nielsen, Janusz K. Rybakowski, Pawel Wojciak, Silvana Galderisi, Gabriele Sachs

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

IntroductionIn this study we assessed the contribution of psychopathology, including the two domains of negative symptoms (motivational deficit and expressive deficit), processing speed as an index of neurocognition, and emotion recognition, as an in

Externí odkaz: https://doaj.org/article/01a986a641024181a0f3284e763cd995

Efficacy of oral versus long-acting antipsychotic treatment in patients with early-phase schizophrenia in Europe and Israel: a large-scale, open-label, randomised trial (EULAST)

Autor: Inge Winter-van Rossum, Mark Weiser, Silvana Galderisi, Stefan Leucht, Istvan Bitter, Birte Glenthøj, Alkomiet Hasan, Jurjen Luykx, Marina Kupchik, Georg Psota, Paola Rocca, Nikos Stefanis, Alexander Teitelbaum, Mor Bar Haim, Claudia Leucht, Georg Kemmler, Timo Schurr, Michael Davidson, René S Kahn, W Wolfgang Fleischhacker, René Sylvain Kahn, Walter Wolfgang Fleischhacker, Monica Mosescu, George Umoh, Lucho Hranov, Alex Hofer, Joachim Cordes, Ramin Nilforooshan, Julio Bobes, Solveig Klebo Reitan, Manuel Morrens, Aurel Nirestean, John Geddes, Benedicto Crespo Faccorro, Marcin Olajossy, Alessandro Rossi, Erik Johnsen, Csekey László, Adela Ciobanu, Peter Haddad, Igor Oife, Miquel Bernardo, Rodicutza Stan, Marek Jarema, Dan Rujescu, Libor Ustohal, Neil Mayfield, Paola Dazzan, Avi Valevski, Jan Libiger, Richard Köhler, Pavel Mohr, Sofia Pappa, Petros Drosos, Thomas Barnes, Esther DeClercq, Elias Wagner, Paola Bucci, Armida Mucci, Yaacov Rabinowitz, Adam Adamopoulous, Benjamin Draiman, Cristiana Montemagni, Manfred Greslechner, Hannah Herlihy, Csilla Bolyos, Christian Schmidt-Kraepelin, Jessica TRUE, Leticia Alvarez Garcia, Berit Walla, Bernhard Sabbe, Lucaks Emese, Sarah Mather, Nikodem Skoczen, Serena Parnanzone, Jill Bjarke, Krisztina Karácsonyi, Steve Lankshear, Marina Garriga, Adam Wichniak, Heidi Baumbach, Leonie Willebrands, Lyliana Nasib, Cynthia Okhuijsen-Pfeifer, Elianne Huijsman

Background: Schizophrenia is a severe psychiatric disorder with periods of remission and relapse. As discontinuation of antipsychotic medication is the most important reason for relapse, long-term maintenance treatment is key. Whether intramuscular l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0252d99fe09e3f8a3c30eba9decf644d
https://hdl.handle.net/11591/497989

Mismatch Negativity in Patients with Schizophrenia

Autor: Aleš Urban, Jan Kremláček, Jan Libiger

Publikováno v: Acta Medica, Vol 50, Iss 1, Pp 23-28 (2007)

Cognitive deficit is considered to be a part of core dysfuncions in schizophrenia. It is associated with social impairment and influences the long-term course of the disorder. In addition to neuropsychological methods, event-related potentials can be

Externí odkaz: https://doaj.org/article/453136dd91c54458b215114ce6afce81

A large European, multicenter, multinational validation study of the Brief Negative Symptom Scale

Autor: Jan Hubeňák, Stefan Kaiser, Armida Mucci, W. Wolfgang Fleischhacker, Gabriele Sachs, Andreas Erfurth, Sonia Dollfus, Jan Libiger, Ingrid Melle, Stephen F. Austin, Paweł Wójciak, Karoline Gütter, István Bitter, Birte Glenthøj, Alp Üçok, A. Vignapiano, Mette Ødegaard Nielsen, Oleg Papsuev, Alex Hofer, Camille Delouche, Igor Gladyshev, Giulia Maria Giordano, Silvana Galderisi, Janusz K. Rybakowski

Publikováno v: Mucci, A, Vignapiano, A, Bitter, I, Austin, S F, Delouche, C, Dollfus, S, Erfurth, A, Fleischhacker, W W, Giordano, G M, Gladyshev, I, Glenthøj, B, Gütter, K, Hofer, A, Hubeňák, J, Kaiser, S, Libiger, J, Melle, I, Nielsen, M Ø, Papsuev, O, Rybakowski, J K, Sachs, G, Üçok, A, Wojciak, P & Galderisi, S 2019, ' A large European, multicenter, multinational validation study of the Brief Negative Symptom Scale ', European Neuropsychopharmacology, vol. 29, no. 8, pp. 947-959 . https://doi.org/10.1016/j.euroneuro.2019.05.006
European Neuropsychopharmacology, Vol. 29, No 8 (2019) pp. 947-959

Negative symptoms represent an unmet need of treatment in schizophrenia. Although a consensus exists on negative symptom construct, and second generation assessment instruments reflecting the consensus are available, studies still rely upon old asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9541ee1f224aeff1afcf6d32beae72f8
https://pubmed.ncbi.nlm.nih.gov/31255394

Correlates of cognitive impairment in first episode schizophrenia: The EUFEST study

Autor: Silvana, Galderisi, Michael, Davidson, René S, Kahn, Armida, Mucci, Han, Boter, Mihai D, Gheorghe, Janusz K, Rybakowski, Jan, Libiger, Sonia, Dollfus, Juan J, López-Ibor, Joseph, Peuskens, Luchezar G, Hranov, Wolfgang W, Fleischhacker, U, Gschwandtner

Publikováno v: Schizophrenia Research. 115:104-114

Background: Profile and correlates of cognitive deficits in first episode (FE) schizophrenia patients are still debated. The present study is aimed to clarify in a large sample of FIE patients the extent of impairment in key cognitive domains and its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a6de0c00352085b25218a5e394aeee
https://doi.org/10.1016/j.schres.2009.09.022