THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

Autor: Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Fabbro, Doriano, Spedding, Michael, Striessnig, Jorg, Davies, Jamie A, Abbracchio, MP, Aldrich, R, Al-Hosaini, K, Arumugam, TV, Attali, B, Back, M, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Bettler, B, Biel, M, Birdsall, NJ, Blaho, V, Boison, D, Brauner-Osborne, H, Broer, S, Bryant, C, Burnstock, G, Calo, G, Catterall, WA, Ceruti, S, Chan, SL, Chandy, KG, Chazot, P, Chiang, N, Chun, JJ, Chung, JJ, Clapham, DE, Clapp, L, Connor, MA, Cox, HM, Davies, P, Dawson, PA, Decaen, P, Dent, G, Doherty, P, Douglas, SD, Dubocovich, ML, Fong, TM, Fowler, CJ, Frantz, A, Fuller, P, Fumagalli, M, Futerman, AH, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, S, Goudet, C, Gregory, K, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hamann, J, Hammond, JR, Hancox, JC, Hanson, J, Hanukoglu, I, Hay, DL, Hobbs, AJ, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Irving, AJ, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, MF, Jensen, R, Jockers, R, Kaczmarek, LK, Kanai, Y, Karnik, S, Kellenberger, S, Kemp, S, Kennedy, C, Kerr, ID, Kihara, Y, Kukkonen, J, Larhammar, D, Leach, K, Lecca, D, Leeman, S, Leprince, J, Lolait, SJ, Macewan, D, Maguire, JJ, Marshall, F, Mazella, J, Mcardle, CA, Michel, MC, Miller, LJ, Mizuno, H, Monk, PN, Mouillac, B, Murphy, PM, Nahon, JL, Nerbonne, J, Nichols, CG, Norel, X, Offermanns, S, Palmer, LG, Panaro, MA, Papapetropoulos, A, Perez-Reyes, E, Pertwee, RG, Pisegna, JR, Plant, LD, Poyner, DR, Prossnitz, ER, Pyne, S, Ramachandran, R, Ren, D, Rondard, P, Ruzza, C, Sackin, H, Sanger, G, Sanguinetti, MC, Schild, L, Schioth, H, Schulte, G, Schulz, S, Segaloff, DL, Serhan, CN, Singh, KD, Slesinger, PA, Snutch, TP, Sobey, CG, Stewart, G, Stoddart, LA, Summers, RJ, Szabo, C, Thwaites, D, Toll, L, Trimmer, JS, Tucker, S, Vaudry, H, Verri, T, Vilargada, JP, Waldman, SA, Ward, DT, Waxman, SG, Wei, AD, Willars, GB, Wong, SS, Woodruff, TM, Wulff, H, Ye, RD, Yung, Y, Zajac, JM, Collaborators, CGTP

Publikováno v: BRITISH JOURNAL OF PHARMACOLOGY

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::4aeeaa833a354c8a07c0337eb638bcf6

Identification of motor neurons and a mechanosensitive sensory neuron in the defecation circuitry of Drosophila larvae

Autor: Jan, Lily, Jan, Yuh, Zhang, W, Yan, Z, Li, B, Jan, LY, Jan, YN

Publikováno v: Jan, Lily; Jan, Yuh; Zhang, W; Yan, Z; Li, B; Jan, LY; et al.(2014). Identification of motor neurons and a mechanosensitive sensory neuron in the defecation circuitry of Drosophila larvae. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6gk71635

© Zhang et al.Defecation allows the body to eliminate waste, an essential step in food processing for animal survival. In contrast to the extensive studies of feeding, its obligate counterpart, defecation, has received much less attention until rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::a4b78663512c130164e1adb92ef7e27d
http://www.escholarship.org/uc/item/6gk71635

Targeting potassium channels in cancer

Autor: Jan, Lily, Huang, X, Jan, LY

Publikováno v: Jan, Lily; Huang, X; & Jan, LY. (2014). Targeting potassium channels in cancer. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0t06595g

Potassium channels are pore-forming transmembrane proteins that regulate a multitude of biological processes by controlling potassium flow across cell membranes. Aberrant potassium channel functions contribute to diseases such as epilepsy, cardiac ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::5c17e287c4500b4ef97552e553d7a4a6
http://www.escholarship.org/uc/item/0t06595g

Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC)

Autor: Tien, J, Lee, HY, Minor, DL, Jan, YN, Jan, LY

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 110, iss 16
Tien, J; Lee, HY; Minor, DL; Jan, YN; & Jan, LY. (2013). Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6352-6357. doi: 10.1073/pnas.1303672110. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/9cf2p049

Transmembrane proteins with unknown function 16 (TMEM16A) is a calcium-activated chloride channel (CaCC) important for neuronal, exocrine, and smooth muscle functions. TMEM16A belongs to a family of integral membrane proteins that includes another Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::97ace9e1be5a23b054018590422c1251
https://escholarship.org/uc/item/9cf2p049

Contribution of visual and circadian neural circuits to memory for prolonged mating induced by rivals

Autor: Jan, Lily, Jan, Yuh, Kim, WJ, Jan, LY, Jan, YN

Publikováno v: Jan, Lily; Jan, Yuh; Kim, WJ; Jan, LY; & Jan, YN. (2012). Contribution of visual and circadian neural circuits to memory for prolonged mating induced by rivals. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3375f8wk

Rival exposure causes Drosophila melanogaster males to prolong mating. Longer mating duration (LMD) may enhance reproductive success, but its underlying mechanism is currently unknown. We found that LMD is context dependent and can be induced solely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::2044568bf95097c151987169fed6f1c5
http://www.escholarship.org/uc/item/3375f8wk