Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jan, Krouželka"'
Autor:
Igor Linhart, Petr Mikeš, Václav Šístek, Antonín Králík, Emil Frantík, Jan Krouželka, Jaroslav Mráz
Publikováno v:
Journal of Applied Toxicology. 33:516-520
Metabolism of benzene, an important environmental and industrial carcinogen, produces three electrophilic intermediates, namely, benzene oxide and 1,2- and 1,4-benzoquinone, capable of reacting with the DNA. Numerous DNA adducts formed by these metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb581ca8cbaec0926a66776785260bc
https://doi.org/10.1002/jat.2716
https://doi.org/10.1002/jat.2716
Autor:
Igor Linhart, Jan Krouželka
Publikováno v:
European Journal of Organic Chemistry. 2009:6336-6340
A simple convenient method has been developed for the preparation of N-acetyl-S-arylcysteines based on the Chan–Lam–Evans arylation of N,N′-diacetylcystine dimethyl ester with arylboronic acids and used to synthesize a series of arylmercapturic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::631f1dffe8148d8eb222e263a1ee3cf4
https://doi.org/10.1002/ejoc.200900982
https://doi.org/10.1002/ejoc.200900982
Autor:
Emil Frantík, Lenka Neufussová, Marek Kořínek, Ľudmila Vodičková, Petr Mikeš, Igor Linhart, Jan Krouželka
Publikováno v:
Toxicology Letters. 184:33-37
New urinary adenine adducts, 3-(2-hydroxy-1-phenylethyl)adenine (N3alphaA), 3-(2-hydroxy-2-phenylethyl)adenine (N3betaA), were found in the urine of mice exposed to styrene vapour. These styrene 7,8-oxide derived adenine adducts as well as previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef032ccc647f3faf4ed90c704ab3ea1
https://doi.org/10.1016/j.toxlet.2008.10.010
https://doi.org/10.1016/j.toxlet.2008.10.010
Publikováno v:
Toxicology letters. 213(2)
New metabolites of styrene, three isomeric vinylphenylmercapturic acids (2-, 3-, and 4-VPMA), were recently identified by LC–ESI-MS in the urine of mice. In this study, 4-VPMA together with traces of 2- and 3-VPMA were found also in the urine of ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58685508378eea848ecca6d44100e3e
https://pubmed.ncbi.nlm.nih.gov/22750350
https://pubmed.ncbi.nlm.nih.gov/22750350
Autor:
Petr, Mikeš, Václav, Sístek, Jan, Krouželka, Antonín, Králík, Emil, Frantík, Jaroslav, Mráz, Igor, Linhart
Publikováno v:
Journal of applied toxicology : JAT. 33(6)
Metabolism of benzene, an important environmental and industrial carcinogen, produces three electrophilic intermediates, namely, benzene oxide and 1,2- and 1,4-benzoquinone, capable of reacting with the DNA. Numerous DNA adducts formed by these metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48d8f0c6abd4808aba7fc65473bef4db
https://pubmed.ncbi.nlm.nih.gov/22336960
https://pubmed.ncbi.nlm.nih.gov/22336960
Autor:
Ludmila Dabrowská, Igor Linhart, Marek Kořínek, Petr Mikeš, Vladimír Stránský, Jaroslav Mráz, Jan Krouželka
Publikováno v:
Toxicology letters. 197(3)
Urine samples from humans occupationally exposed to styrene, with mandelic acid levels ranging from 400 to 1145 mg/g creatinine and from 68 to 400mg/g creatinine for high and low exposure group, respectively, were analysed for N3 adenine DNA adducts,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add0307676c54ee96cdf10e29ae7dda4
https://pubmed.ncbi.nlm.nih.gov/20553827
https://pubmed.ncbi.nlm.nih.gov/20553827
Autor:
Igor Linhart, Jaroslav Mráz, Jan Scharff, Jan Krouželka, Šárka Dušková, Hana Nohová, L’udmila Vodičková
Publikováno v:
Chemical Research in Toxicology; Jan2010, Vol. 23 Issue 1, p251-257, 7p