Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jan, Kazenwadel"'
Autor:
Anna E. Williamson, Sanuri Liyanage, Mohammadhossein Hassanshahi, Malathi S. I. Dona, Deborah Toledo-Flores, Dang X. A. Tran, Catherine Dimasi, Nisha Schwarz, Sanuja Fernando, Thalia Salagaras, Aaron Long, Jan Kazenwadel, Natasha L. Harvey, Grant R. Drummond, Antony Vinh, Vashe Chandrakanthan, Ashish Misra, Zoltan Neufeld, Joanne T. M. Tan, Luciano Martelotto, Jose M. Polo, Claudine S. Bonder, Alexander R. Pinto, Shiwani Sharma, Stephen J. Nicholls, Christina A. Bursill, Peter J. Psaltis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Converging evidence indicates that extra-embryonic yolk sac is the source of both macrophages and endothelial cells in adult mouse tissues. Prevailing views are that these embryonically derived cells are maintained after birth by proliferati
Externí odkaz:
https://doaj.org/article/d2b62685f49a4c7f8deedee2fe7c08c9
Autor:
Maike Frye, Andrea Taddei, Cathrin Dierkes, Ines Martinez-Corral, Matthew Fielden, Henrik Ortsäter, Jan Kazenwadel, Dinis P. Calado, Pia Ostergaard, Marjo Salminen, Liqun He, Natasha L. Harvey, Friedemann Kiefer, Taija Mäkinen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Mechanical cues are known to influence endothelial cell behavior. Here Frye et al. show that lymphatic endothelial cell progenitors experience varying degrees of matrix stiffness during development, and that matrix stiffness regulates GATA2 expressio
Externí odkaz:
https://doaj.org/article/d7157b72d40e47f885661cb7f76b2542
Autor:
Ivy K N Chiang, Matthew S Graus, Nils Kirschnick, Tara Davidson, Winnie Luu, Richard Harwood, Keyi Jiang, Bitong Li, Yew Yan Wong, Mehdi Moustaqil, Emmanuelle Lesieur, Renae Skoczylas, Valerie Kouskoff, Jan Kazenwadel, Luis Arriola‐Martinez, Emma Sierecki, Yann Gambin, Kari Alitalo, Friedmann Kiefer, Natasha L Harvey, Mathias Francois
Refereed/Peer-reviewed Despite a growing catalog of secreted factors critical for lymphatic network assembly, little is known about the mechanisms that modulate the expression level of these molecular cues in blood vascular endothelial cells (BECs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b743e950455b85e2c844ab2d4d566703
https://hdl.handle.net/11541.2/32559
https://hdl.handle.net/11541.2/32559
Autor:
Jan Kazenwadel, Parvathy Venugopal, Anna Oszmiana, John Toubia, Luis Arriola-Martinez, Virginia Panara, Sandra G. Piltz, Chris Brown, Wanshu Ma, Andreas W. Schreiber, Katarzyna Koltowska, Samir Taoudi, Paul Q. Thomas, Hamish S. Scott, Natasha L. Harvey
Refereed/Peer-reviewed Transcriptional enhancer elements are responsible for orchestrating the temporal and spatial control over gene expression that is crucial for programming cell identity during development. Here we describe a novel enhancer eleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350e247748b9d07be7b8263cc0bfd4cf
https://hdl.handle.net/11541.2/32594
https://hdl.handle.net/11541.2/32594
Autor:
Alicia B, Byrne, Pascal, Brouillard, Drew L, Sutton, Jan, Kazenwadel, Saba, Montazaribarforoushi, Genevieve A, Secker, Anna, Oszmiana, Milena, Babic, Kelly L, Betterman, Peter J, Brautigan, Melissa, White, Sandra G, Piltz, Paul Q, Thomas, Christopher N, Hahn, Matthias, Rath, Ute, Felbor, G Christoph, Korenke, Christopher L, Smith, Kathleen H, Wood, Sarah E, Sheppard, Denise M, Adams, Ariana, Kariminejad, Raphael, Helaers, Laurence M, Boon, Nicole, Revencu, Lynette, Moore, Christopher, Barnett, Eric, Haan, Peer, Arts, Miikka, Vikkula, Hamish S, Scott, Natasha L, Harvey
Publikováno v:
Science translational medicine. 14(634)
Central conducting lymphatic anomaly (CCLA), characterized by the dysfunction of core collecting lymphatic vessels including the thoracic duct and cisterna chyli, and presenting as chylothorax, pleural effusions, chylous ascites, and lymphedema, is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d4178329aba45f643084d569782c198
https://pubmed.ncbi.nlm.nih.gov/35235341
https://pubmed.ncbi.nlm.nih.gov/35235341
Autor:
Emily L. Paterson, Jan Kazenwadel, Andrew G. Bert, Yeesim Khew-Goodall, Andrew Ruszkiewicz, Gregory J. Goodall
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 2, Pp 180-191 (2013)
Cancer progression is a complex series of events thought to incorporate the reversible developmental process of epithelial-to-mesenchymal transition (EMT). In vitro, the microRNA-200 family maintains the epithelial phenotype by posttranscriptionally
Externí odkaz:
https://doaj.org/article/a8b063cc0efe48c5b50992191e57dcb2
Autor:
Alicia B. Byrne, Pascal Brouillard, Drew L. Sutton, Jan Kazenwadel, Saba Montazaribarforoushi, Genevieve A. Secker, Anna Oszmiana, Milena Babic, Kelly L. Betterman, Peter J. Brautigan, Melissa White, Sandra G. Piltz, Paul Q. Thomas, Christopher N. Hahn, Matthias Rath, Ute Felbor, G. Christoph Korenke, Christopher L. Smith, Kathleen H. Wood, Sarah E. Sheppard, Denise M. Adams, Ariana Kariminejad, Raphael Helaers, Laurence M. Boon, Nicole Revencu, Lynette Moore, Christopher Barnett, Eric Haan, Peer Arts, Miikka Vikkula, Hamish S. Scott, Natasha L. Harvey
Publikováno v:
Science Translational Medicine, Vol. 14, no. 634 (2022) (2022)
Central conducting lymphatic anomaly (CCLA), characterized by the dysfunction of core collecting lymphatic vessels including the thoracic duct and cisterna chyli, and presenting as chylothorax, pleural effusions, chylous ascites, and lymphedema, is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5954867de8c3ef147a7cbf3815f11d
https://hdl.handle.net/2078.1/260107
https://hdl.handle.net/2078.1/260107
Autor:
Belinda A. Di Bartolo, Thalia Salagaras, Aaron Long, Grant R Drummond, Jan Kazenwadel, Natasha L. Harvey, N. Schwarz, Claudine S. Bonder, Christina A. Bursill, A. Williamson, Ashish Misra, Antony Vinh, Joanne T.M. Tan, Vashe Chandrakanthan, C. Dimasi, Peter J. Psaltis, Stephen J. Nicholls, S. Fernando, Mohammadhossein Hassanshahi, Sanuri Liyanage, Deborah Toledo-Flores
SUMMARYConverging evidence indicates that extra-embryonic yolk sac is the source of both macrophages and endothelial cells in adult mouse tissues. Prevailing views are that these yolk sac-derived cells are maintained after birth by proliferative self
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a0ac8af0320590a1d83026d68a4fd29
https://doi.org/10.1101/2021.10.18.464001
https://doi.org/10.1101/2021.10.18.464001
Autor:
Genevieve A. Secker, Kelly L. Betterman, Helen McNeill, Benjamin M. Hogan, Lydia Sorokin, Drew L. Sutton, Lillian Lim, Naoyuki Miura, Mark L. Kahn, Natasha L. Harvey, Anna Oszmiana, Jan Kazenwadel
Publikováno v:
J Clin Invest
The atypical cadherin FAT4 has established roles in the regulation of planar cell polarity and Hippo pathway signaling that are cell context dependent. The recent identification of FAT4 mutations in Hennekam syndrome, features of which include lymphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd2f171bc08ea852ea558f3c4bb5a70
https://europepmc.org/articles/PMC7260025/
https://europepmc.org/articles/PMC7260025/
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40497 (2012)
Despite the importance of blood vessels and lymphatic vessels during development and disease, the signalling pathways underpinning vessel construction remain poorly characterised. Primary mouse endothelial cells have traditionally proven difficult to
Externí odkaz:
https://doaj.org/article/f8be11870cf94785bd04f79fb921b110