Zobrazeno 1 - 10
of 424
pro vyhledávání: '"Jan, Holmgren"'
Autor:
Manuela Terrinoni, Stefan L. Nordqvist, Madeleine Löfstrand, Frida Nilsson, Susanne Källgård, Tarun Sharma, Michael R. Lebens, Jan Holmgren
Publikováno v:
Vaccine. 41:3347-3357
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5b798f3a4d59d915a5e3e95ec9c01a4
https://doi.org/10.1016/j.vaccine.2023.04.004
https://doi.org/10.1016/j.vaccine.2023.04.004
Autor:
Audur Anna Aradottir Pind, Magdalena Dubik, Sigrun Thorsdottir, Andreas Meinke, Ali M. Harandi, Jan Holmgren, Giuseppe Del Giudice, Ingileif Jonsdottir, Stefania P. Bjarnarson
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited due to poorly developed follicular dendritic cells (FDC), causing generation of few antibody-secreting cells (ASCs) with l
Externí odkaz:
https://doaj.org/article/d945f6a4291c465eb5fe81ced81f0e1a
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cholera toxin (CT) is widely used as an effective adjuvant in experimental immunology for inducing mucosal immune responses; yet its mechanisms of adjuvant action remain incompletely defined. Here, we demonstrate that mice lacking NFκB, compared to
Externí odkaz:
https://doaj.org/article/855d952e222a49bdb87a51cbecc79730
Autor:
Jan Holmgren
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 6, Iss 2, p 64 (2021)
Individual resistance to cholera infection and disease depends on both innate host factors and adaptive immunity acquired by a previous infection or vaccination. Locally produced, intestinal-mucosal secretory IgA (SIgA) antibodies against bacterial s
Externí odkaz:
https://doaj.org/article/f650497dd41d4500baf56181928a664d
Autor:
Anu Kantele, Marianna Riekkinen, T Sakari Jokiranta, Sari H Pakkanen, Jukka-Pekka Pietilä, Anu Patjas, Mari Eriksson, Tamim Khawaja, Peter Klemets, Kati Marttinen, Heli Siikamäki, Anna Lundgren, Jan Holmgren, Agneta Lissmats, Nils Carlin, Ann-Mari Svennerholm
Publikováno v:
Journal of Travel Medicine.
Background No licensed human vaccines are available against enterotoxigenic Escherichia coli (ETEC), a major diarrhoeal pathogen affecting children in low- and middle-income countries and foreign travellers alike. ETVAX®, a multivalent oral whole-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9d5b35492e7c78c5d1afeaf264fad5f
https://doi.org/10.1093/jtm/taad045
https://doi.org/10.1093/jtm/taad045
Autor:
Jan Holmgren
Publikováno v:
The Journal of Infectious Diseases
The rapid spread of the 7 th cholera pandemic over Asia in the 1960s led to several large field studies that revealed that the traditional injectable cholera vaccines had poor efficacy, usually less than 50% for only 3-6 months, which led WHO in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da31c708cea223e84c67971a90dfab6b
https://doi.org/10.1093/infdis/jiab423
https://doi.org/10.1093/infdis/jiab423
Autor:
Jia-Bin Sun, Jan Holmgren, Maximilian Larena, Manuela Terrinoni, Yu Fang, Anne R. Bresnick, Zou Xiang
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The calcium-binding protein S100A4 has been described to promote pathological inflammation in experimental autoimmune and inflammatory disorders and in allergy and to contribute to antigen presentation and antibody response after parenteral immunizat
Externí odkaz:
https://doaj.org/article/9e1df58a76404decb34f7a215451a2e5
Autor:
Imam Tauheed, Hasan Al Banna, Khalid Ali Syed, Nigel Mc Millan, Vibhu Kanchan, Tarun Sharma, Jannatul Ferdous, Davinder Gill, Michael Lebens, Firdausi Qadri, Jan Holmgren, Ajit Pal Singh, Allen G. Ross, Afroza Akter, Stefan Nordqvist, Fahima Chowdhury, Fatema Khaton, Taufiqur Rahman Bhuiyan, Rajib Biswas, John D. Clemens
Publikováno v:
Vaccine. 39:4450-4457
The World Health Organization (WHO) recommends the use of oral cholera vaccines (OCVs) as part of an integrated control program, both in highly endemic settings and during cholera epidemics. The available and internationally recommended WHO-prequalif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63842e7ef63f3a20a55913d63035d5ae
https://doi.org/10.1016/j.vaccine.2021.06.069
https://doi.org/10.1016/j.vaccine.2021.06.069
Autor:
Stefan L Karlsson, Nicholas Thomson, Ankur Mutreja, Thomas Connor, Dipika Sur, Mohammad Ali, John Clemens, Gordon Dougan, Jan Holmgren, Michael Lebens
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005044 (2016)
Genomic data generated from clinical Vibrio cholerae O1 isolates collected over a five year period in an area of Kolkata, India with seasonal cholera outbreaks allowed a detailed genetic analysis of serotype switching that occurred from Ogawa to Inab
Externí odkaz:
https://doaj.org/article/bea359d7e1f448deacc8b0824e99c638
Autor:
Erika Rehnström, Thomas Lundböck, Anna Novén, Jan Holmgren, Linda Fredlund, Johan Wernevik, Fredrik Bergström, Dan Addison, Johan Hulthe, Per-Erik Strömstedt
Publikováno v:
Assay and Drug Development Technologies
Evaluation and optimization of physicochemical and metabolic properties of compounds are a crucial component of the drug development process. Continuous access to this information during the design-make-test-analysis cycle enables identification of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14e880c484c3f3b630ddc5a788747f0
https://doi.org/10.1089/adt.2020.970
https://doi.org/10.1089/adt.2020.970