Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Jan, Grimm"'
Autor:
Pavitra Sokke Rudraiah, Rafael Camacho, Julia Fernandez-Rodriguez, Dror Fixler, Jan Grimm, Florian Gruber, Matúš Kalaš, Christopher Kremslehner, Claudia Kuntner, Daniela Kuzdas-Wood, Joakim Lindblad, Julia G. Mannheim, Martina Marchetti-Deschmann, Perrine Paul-Gilloteaux, Paula Sampaio, Peter Sandbichler, Anna Sartori-Rupp, Nataša Sladoje, Paul Verkade, Andreas Walter, Samuele Zoratto
Publikováno v:
Frontiers in Biomaterials Science, Vol 3 (2024)
Correlated Multimodal Imaging (CMI) gathers information about the same specimen with two or more modalities that–combined–create a composite and complementary view of the sample (including insights into structure, function, dynamics and molecular
Externí odkaz:
https://doaj.org/article/eb41651dc2764ea8a77530804b8dcd18
Autor:
Fabian Wirth, Fabrice D. Heitz, Christine Seeger, Ioana Combaluzier, Karin Breu, Heather C. Denroche, Julien Thevenet, Melania Osto, Paolo Arosio, Julie Kerr-Conte, C. Bruce Verchere, François Pattou, Thomas A. Lutz, Marc Y. Donath, Christoph Hock, Roger M. Nitsch, Jan Grimm
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract In patients with type 2 diabetes, pancreatic beta cells progressively degenerate and gradually lose their ability to produce insulin and regulate blood glucose. Beta cell dysfunction and loss is associated with an accumulation of aggregated
Externí odkaz:
https://doaj.org/article/68eb80d31bdf42208e648a12724a93bf
Autor:
Anton G. Windfelder, Frank H. H. Müller, Benedict Mc Larney, Michael Hentschel, Anna Christina Böhringer, Christoph-Rüdiger von Bredow, Florian H. Leinberger, Marian Kampschulte, Lorenz Maier, Yvette M. von Bredow, Vera Flocke, Hans Merzendorfer, Gabriele A. Krombach, Andreas Vilcinskas, Jan Grimm, Tina E. Trenczek, Ulrich Flögel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Here, combining diagnostic imaging modalities and in vivo assays, Windfelder and colleagues established tobacco hornworm larvae Manduca sexta as an alternative high-throughput platform to study the innate immunity of the gut and host-pathogen interac
Externí odkaz:
https://doaj.org/article/9668adf745994426b747db4dce0c69da
Autor:
Aubin Michalon, Andreas Hagenbuch, Christian Huy, Evita Varela, Benoit Combaluzier, Thibaud Damy, Ole B. Suhr, Maria J. Saraiva, Christoph Hock, Roger M. Nitsch, Jan Grimm
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Analyzing memory B cell repertoires of the healthy elderly enabled Michalon et al. to develop a recombinant human antibody selective for transthyretin amyloid. This antibody removes cardiac amyloid through recruitment of phagocytic immune cells.
Externí odkaz:
https://doaj.org/article/0bd15e092d1f47498ea907338e89a448
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Cerenkov luminescence is a blue-weighted emission of light produced by a vast array of clinically approved radioisotopes and LINAC accelerators. When β particles (emitted during the decay of radioisotopes) are present in a medium such as water or ti
Externí odkaz:
https://doaj.org/article/699ec10c9086496aa1cc6b0e6debab56
Autor:
Franziska Schindler, Nicole Praedel, Nancy Neuendorf, Severine Kunz, Sigrid Schnoegl, Michael A. Mason, Bridget A. Taxy, Gillian P. Bates, Ali Khoshnan, Josef Priller, Jan Grimm, Marcel Maier, Annett Boeddrich, Erich E. Wanker
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The deposition of mutant huntingtin (mHTT) protein aggregates in neurons of patients is a pathological hallmark of Huntington’s disease (HD). Previous investigations in cell-free and cell-based disease models showed mHTT exon-1 (mHTTex1) fragments
Externí odkaz:
https://doaj.org/article/39b7832b713b418b99c771d5d66fad70
Autor:
Andreas Weihofen, YuTing Liu, Joseph W. Arndt, Christian Huy, Chao Quan, Benjamin A. Smith, Jean-Luc Baeriswyl, Nicole Cavegn, Luzia Senn, Lihe Su, Galina Marsh, Pavan K. Auluck, Fabio Montrasio, Roger M. Nitsch, Warren D. Hirst, Jesse M. Cedarbaum, R. Blake Pepinsky, Jan Grimm, Paul H. Weinreb
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 276-288 (2019)
Aggregation of α-synuclein (α-syn) is neuropathologically and genetically linked to Parkinson's disease (PD). Since stereotypic cell-to-cell spreading of α-syn pathology is believed to contribute to disease progression, immunotherapy with antibodi
Externí odkaz:
https://doaj.org/article/9c312d730f4444538aa0bb5f11e8cda5
Autor:
Evan P. Stater, George Morcos, Elizabeth Isaac, Anuja Ogirala, Hsiao-Ting Hsu, Valerie A. Longo, Jan Grimm
Publikováno v:
ACS Nano. 17:6178-6192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4797d3d4adc70a5836b3c2305cc4b5ae
https://doi.org/10.1021/acsnano.2c05800
https://doi.org/10.1021/acsnano.2c05800
Autor:
Eileen M. Geoghegan, Diana V. Pastrana, Rachel M. Schowalter, Upasana Ray, Wei Gao, Mitchell Ho, Gary T. Pauly, Dina M. Sigano, Campbell Kaynor, Ellen Cahir-McFarland, Benoit Combaluzier, Jan Grimm, Christopher B. Buck
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1169-1179 (2017)
Summary: Progressive multifocal leukoencephalopathy (PML) is a lethal brain disease caused by uncontrolled replication of JC polyomavirus (JCV). JCV strains recovered from the brains of PML patients carry mutations that prevent the engagement of sial
Externí odkaz:
https://doaj.org/article/940b16d5a0d7411789fc82a19047a02f
Autor:
Jay A. Berzofsky, Lauren Gerard Koch, Steven L. Britton, Shaochen Chen, Wei Zhu, Xuanyi Ma, Anthony G. Comuzzie, Laetitia Devy-Dimanche, Ryan Feaver, Jan Grimm, Christoph Hock, Roger M. Nitsch, James B. Hoying, Aldons J. Lusis, Francesco Marincola, Josue Samayoa, Tolga Turan, David A. Pearce, Antti Nurmi, Tuulia Huhtala, Artem Shatillo, Jukka Puoliväli, Taneli Heikkinen, Timo Bragge, Kimmo Lehtimäki, Arun J. Sanyal, Kevin Strange, D. Lansing Taylor, Mark Miedel, Shanhang Jia, Alex Soto-Guterriez, Andrew Stern, Albert Gough
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss S3, Pp 1-7 (2017)
Externí odkaz:
https://doaj.org/article/495726c749064892a0b63dd7bba85d72