A randomized controlled trial of the effect of spironolactone on left ventricular mass in hemodialysis patients

Autor: Sebastian Toncar, Thomas Schmiedeke, Thomas Vogl, Nils Pollak, Michael Leidig, Beatrix Büschges-Seraphin, Marianne Kleinert, Cord Schneuzer, Christina Klaeffling, Clemens Grupp, Christoph Blaser, Susanne Berweck, Rüdiger Götz, Stefan Fischer, Andreas Schmitt, Bettina Wirth, Frank Breunig, Markus Ketteler, Hendrick Witsch, Frank Strutz, Uwe Malzahn, Oliver Jung, Markus Schneider, Julian Gebhardt, Jan Goßmann, Mohamed Marwan, Holger Naujoks, Mara Dörken, L. Schramm, Ewelina Sobkowiak, Michael Heckel, Joanna Harazny, Arnfried Klingbeil, J Zimmermann, Maria Moritz, Heribert Fink, Raoul Zeltner, Patrick Biggar, Rolf Janka, Ahmet Cakmak, Stefan Büttner, Christoph Betz, Fabian Hammer, Heike Schneider, Sarah Rudolf, Beate Schamberger, Imke Reimer, Claudius Kleinert, Michael Brunner, Sabine Schütterle, Susanne Schwedler, Vera Krane, Thorsten Klink, Sophie Richter, Christian Ritter, Markus Schöffauer, Tilo Freiwald, Helmut Geiger, Ulrike Raff, Benjamin-Florian Koch, Renate Hammerstingl, Thomas Bochannek, Joachim Hoyer, Wolfgang Freisinger, Paul Würmell, Daniel Sollinger, Vladimir Vasiljuk, Michael Schmid, Clemens Reichert, Jens Lutz, Stefan Störk, Reinhard Schneider, Andrea Heyd-Schramm, Thomas Döltz, Brigitte Moye, Kai-Olaf Netzer, Kai-Uwe Eckardt, Jurij Ribel, Christoph Wanner, Julian Donhauser, Thorsten Walther, Julia Weinmann-Menke, Judith Kosowski

Publikováno v: Kidney International. 95:983-991

Mineralocorticoid receptor antagonists have beneficial effects on left ventricular remodeling, cardiac fibrosis, and arrhythmia in heart failure, but efficacy and safety in dialysis patients is less clear. We evaluated the effect of spironolactone on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc8f0e24798b6d023a9deb6f47218d3
https://doi.org/10.1016/j.kint.2018.11.025

Pharmacokinetic Analysis of Mycophenolate Mofetil and Enteric-Coated Mycophenolate Sodium in Calcineurin Inhibitor–Free Renal Transplant Recipients

Autor: Gunnar Brandhorst, Ernst-Heinrich Scheuermann, Jochen Graff, Michael Oellerich, Jan Gossmann

Publikováno v: Therapeutic Drug Monitoring. 38:388-392

Background Considerable interest exists in identifying calcineurin inhibitor (CNI)-free and thus, less-toxic immunosuppressive regimens, with mycophenolic acid (MPA)-based treatments being a suitable approach. Because pharmacokinetic analyses of MPA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f071875d09d45acc43b83a72db6dfa2
https://doi.org/10.1097/ftd.0000000000000281

Development of urological cancers in renal transplant recipients: 30-year experience at the Frankfurt Transplant Center

Autor: Michael Probst, Dietger Jonas, Ernst-Heinrich Scheuermann, Heinz-Georg Kachel, Roman A. Blaheta, Igor Tsaur, Jan Gossmann, Ingeborg A. Hauser, Athanasios Karalis, Nicholas Obermüller

Publikováno v: Cancer Science. 101:2430-2435

Fatal post-transplant malignancies with a high proportion of genitourinary neoplasms represent a serious long-term challenge. With continuous improvement of the allograft and patient survival, cancer development after renal transplantation may soon t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5618f4fe27a15da04618b9e39296b8eb
https://doi.org/10.1111/j.1349-7006.2010.01676.x

Renal transplantation in the elderly: surgical complications and outcome with special emphasis on the Eurotransplant Senior Programme

Autor: Akay Karaoguz, Michael Probst, Jon Jones, Dietger Jonas, Jan Gossmann, Wassilios Bentas, Ernst H. Scheuermann, Ingeborg A. Hauser, Ursula Tilp

Publikováno v: Nephrology Dialysis Transplantation. 23:2043-2051

The purpose of this retrospective study was to evaluate the results of the Eurotransplant Senior Programme (ESP) within our centre compared to elderly recipientsor=60 years from the regular Eurotransplant Kidney Allocation System (ETKAS), specificall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa6b03ef1e96deab41fb823dbb8cc73
https://doi.org/10.1093/ndt/gfm912

Anti-inflammatory effects of clopidogrel intake in renal transplant patients: Effects on platelet-leukocyte interactions, platelet CD40 ligand expression, and proinflammatory biomarkers

Autor: Jan Gossmann, Oliver Wahl, Jochen Graff, Sebastian Harder, Ernst-Heinrich Scheuermann

Publikováno v: Clinical Pharmacology & Therapeutics. 78:468-476

Background Increased platelet activation has been described during treatment with various immunosuppressive agents and may contribute to the high cardiovascular mortality rate in renal transplant patients. Platelets are thought to propagate the infla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b18bdd217954e8ff15a6016ddd510c
https://doi.org/10.1016/j.clpt.2005.08.002