Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jan, Dudeck"'
Autor:
Tobias Ronny Haage, Emmanouil Charakopoulos, Vikas Bhuria, Conny K. Baldauf, Mark Korthals, Juliane Handschuh, Peter Müller, Juan Li, Kunjan Harit, Gopala Nishanth, Stephanie Frey, Martin Böttcher, Klaus-Dieter Fischer, Jan Dudeck, Anne Dudeck, Daniel B. Lipka, Burkhart Schraven, Anthony R. Green, Andreas J. Müller, Dimitrios Mougiakakos, Thomas Fischer
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-23 (2024)
Abstract Background Neutrophils play a crucial role in inflammation and in the increased thrombotic risk in myeloproliferative neoplasms (MPNs). We have investigated how neutrophil-specific expression of JAK2-V617F or CALRdel re-programs the function
Externí odkaz:
https://doaj.org/article/de0cb7b1744d4527b1c4f8287f2223f4
Autor:
Shanawaz Mohammed Ghouse, Anastasia Polikarpova, Lina Muhandes, Jan Dudeck, Iliana Tantcheva-Poór, Karin Hartmann, Matthias Lesche, Andreas Dahl, Sabine Eming, Werner Müller, Rayk Behrendt, Axel Roers
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 27-35 (2018)
Summary: High numbers of mast cells populate the stroma of many types of neoplasms, including human papilloma virus-induced benign and malignant tumors in man and mouse. Equipped with numerous pattern recognition receptors and capable of executing im
Externí odkaz:
https://doaj.org/article/13ba645c949b4ef4bab0bac4439e8e43
Publikováno v:
Cells, Vol 9, Iss 12, p 2538 (2020)
Although mast cells (MCs) are known as key drivers of type I allergic reactions, there is increasing evidence for their critical role in host defense. MCs not only play an important role in initiating innate immune responses, but also influence the o
Externí odkaz:
https://doaj.org/article/b848003f815744f3bbade8350d4b2b15
Autor:
Jan Dudeck, Shanawaz Mohammed Ghouse, Christian H.K. Lehmann, Anja Hoppe, Nadja Schubert, Sergei A. Nedospasov, Diana Dudziak, Anne Dudeck
Publikováno v:
Cell Reports, Vol 13, Iss 2, Pp 399-411 (2015)
Mast cells are critical promoters of adaptive immunity in the contact hypersensitivity model, but the mechanism of allergen sensitization is poorly understood. Using Mcpt5-CreTNFFL/FL mice, we show here that the absence of TNF exclusively in mast cel
Externí odkaz:
https://doaj.org/article/0fc03a3f3bbd47ec95fc0554d2fb1d77
Autor:
Johanna Kotrba, Silke Balk, Konstantinos Katsoulis-Dimitriou, Lars Philipsen, Roland Hartig, Jan Dudeck, Christoph Garbers, Jürgen Ruland, Burkhart Schraven, Andreas J. Mueller, Sascha Kahlfuß, Bernd Lepenies, Anne Dudeck
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c272ff88d2cb822f33eb25326ec85ede
https://doi.org/10.2139/ssrn.4266336
https://doi.org/10.2139/ssrn.4266336
Publikováno v:
Cells
Cells, Vol 9, Iss 2538, p 2538 (2020)
Cells, Vol 9, Iss 2538, p 2538 (2020)
Although Mast cells are known as key drivers of type I allergic reactions, there is increasing evidence for their critical role in host defense. MCs do not only play an important role in initiating innate immune responses, but also influence the onse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c24894748243d5ec0164ae431a21c0
Autor:
Georg Kollias, Vasileia Ismini Alexaki, Aaron Hoffmann, Markus Sperandio, Sergei A. Nedospasov, Johanna Kotrba, Thomas Fischer, Roland Immler, Anne Dudeck, Konstantinos Katsoulis-Dimitriou, Stephan René Jahn, Burkhart Schraven, Triantafyllos Chavakis, Jan Dudeck, Lorena Morton, Simon Winzer, Andreas Müller, Ildiko Rita Dunay, Martin Voss
Publikováno v:
Immunity. 54(3)
Tissue resident mast cells (MCs) rapidly initiate neutrophil infiltration upon inflammatory insult, yet the molecular mechanism is still unknown. Here, we demonstrated that MC-derived tumor necrosis factor (TNF) was crucial for neutrophil extravasati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4cf972f59849e9f3e6dd6ad158bd07
https://pubmed.ncbi.nlm.nih.gov/33542498
https://pubmed.ncbi.nlm.nih.gov/33542498
Autor:
Julia Kemmler, Anne Dudeck, Thorsten Schinke, Anita Ignatius, Michael Amling, Johanna Kotrba, Jan Dudeck, Jochen Kroner, Sebastian Seitz, Julia Froebel, Joanna J. Messmann, Gudrun Strauss, Anna Kovtun
Publikováno v:
Journal of Bone and Mineral Research. 32:2431-2444
Mast cells, important sensor and effector cells of the immune system, may influence bone metabolism as their number is increased in osteoporotic patients. They are also present during bone fracture healing with currently unknown functions. Using a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e995152bdc44e59d2fdd8b14be50e460
https://doi.org/10.1002/jbmr.3234
https://doi.org/10.1002/jbmr.3234
Autor:
Roland Immler, Johanna Kotrba, Aaron Hoffmann, Sergei A. Nedospasov, Vasileia Ismini Alexaki, Andreas J. Mueller, Triantafyllos Chavakis, Lorena Morton, Simon Winzer, Markus Sperandio, Burkhart Schraven, Martin Voss, Ildiko Rita Dunay, Stephan René Jahn, Jan Dudeck, George Kollias, Thomas Fischer, Anne Dudeck
Publikováno v:
SSRN Electronic Journal.
Tissue resident mast cells (MCs) rapidly initiate neutrophil infiltration upon inflammatory insult, yet the molecular mechanism is still unknown. Here, we demonstrate that MC-derived TNF is crucial for neutrophil extravasation to sites of sterile ski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd321c90d64f3640ef92607b2158549
https://doi.org/10.2139/ssrn.3651507
https://doi.org/10.2139/ssrn.3651507
Autor:
Anja Hoppe, Konstantinos Katsoulis-Dimitriou, Hanna J. Edler, Sebastian Drube, Jan Dudeck, Anne Dudeck
Publikováno v:
The Journal of allergy and clinical immunology. 145(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9fdc02efee47382f1bdfca81173f03c
https://pubmed.ncbi.nlm.nih.gov/32018029
https://pubmed.ncbi.nlm.nih.gov/32018029