Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Jan, Drappatz"'
Autor:
Megan Mantica, Jan Drappatz
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Advances clarifying the genetics and function of the immune system within the central nervous system (CNS) and brain tumor microenvironment have led to increasing momentum and number of clinical trials using immunotherapy for primary brain tumors. Wh
Externí odkaz:
https://doaj.org/article/b7ff3c1fe34a4be09bfa0c5d859b0f45
Autor:
Na Tosha N. Gatson, Jill Barnholtz-Sloan, Jan Drappatz, Roger Henriksson, Andreas F. Hottinger, Piet Hinoul, Carol Kruchko, Vinay K. Puduvalli, David D. Tran, Eric T. Wong, Martin Glas
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe COVID-19 pandemic has placed excessive strain on health care systems and is especially evident in treatment decision-making for cancer patients. Glioblastoma (GBM) patients are among the most vulnerable due to increased incidence in the
Externí odkaz:
https://doaj.org/article/bb11cabf61264759a7f38223692b2f5d
Autor:
Kristina Fanucci, Mary Jo Pilat, Derek Shyr, Yu Shyr, Scott Boerner, Jing Li, Diane Durecki, Jan Drappatz, Vinay Puduvalli, Frank Scott Lieberman, Javier Gonzalez, Pierre Giglio, S. Percy Ivy, Ranjit S. Bindra, Antonio Omuro, Patricia LoRusso
Publikováno v:
Cancer Research Communications. 3:192-201
Purpose: Isocitrate dehydrogenase (IDH) 1 and IDH2 mutations (IDH1/2mt) are frequent in glioma. Preclinical studies suggest IDH1/2mts confer “BRCAness” phenotype, a vulnerability that can be targeted through PARP inhibition. To test this hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f49e5afc6bbf0633b5b460924fa41470
https://doi.org/10.1158/2767-9764.crc-22-0436
https://doi.org/10.1158/2767-9764.crc-22-0436
Autor:
Christine A. Garcia, Alex El-Ali, Tanya J. Rath, Lydia C. Contis, Vikram Gorantla, Jan Drappatz, Diwakar Davar
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-6 (2018)
Abstract Background PD-1 and CTLA-4 inhibitors are associated with several adverse events including a spectrum of immune-related adverse effects (irAEs). Neurologic irAEs are uncommon occurrences with varied presentations. We describe two separate ca
Externí odkaz:
https://doaj.org/article/c207564dc39b4723bfaa39525cc241e1
Autor:
Michal Nisnboym Ziv, Sarah R. Vincze, Itay Raphael, Zujian Xiong, Chaim T. Sneiderman, Rebecca A. Raphael, Bo Li, Ambika P. Jaswal, ReidAnn Sever, Kathryn E. Day, Joseph D. LaToche, Lesley M. Foley, T. Kevin Hitchens, Sameer Agnihotri, Baoli Hu, Dhivyaa Rajasundaram, Carolyn J. Anderson, Deborah T. Blumenthal, Thomas M. Pearce, Shikhar Uttam, Jessie R. Nedrow, Ashok Panigrahy, Ian F. Pollack, Frank S. Lieberman, Jan Drappatz, Wilson B. Edwards, Gary Kohanbash
Publikováno v:
Monday, April 24.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f450026d30d089f805e67417d23eb2e9
https://doi.org/10.1212/wnl.0000000000204332
https://doi.org/10.1212/wnl.0000000000204332
Autor:
Patricia LoRusso, Antonio Omuro, Ranjit S. Bindra, S. Percy Ivy, Pierre Giglio, Javier Gonzalez, Frank Scott Lieberman, Vinay Puduvalli, Jan Drappatz, Diane Durecki, Jing Li, Scott Boerner, Yu Shyr, Derek Shyr, Mary Jo Pilat, Kristina Fanucci
Purpose:Isocitrate dehydrogenase (IDH) 1 and IDH2 mutations (IDH1/2mt) are frequent in glioma. Preclinical studies suggest IDH1/2mts confer “BRCAness” phenotype, a vulnerability that can be targeted through PARP inhibition. To test this hypothesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770e848003c7826eb1665f7c2268edfc
https://doi.org/10.1158/2767-9764.c.6551052
https://doi.org/10.1158/2767-9764.c.6551052
Autor:
Patricia LoRusso, Antonio Omuro, Ranjit S. Bindra, S. Percy Ivy, Pierre Giglio, Javier Gonzalez, Frank Scott Lieberman, Vinay Puduvalli, Jan Drappatz, Diane Durecki, Jing Li, Scott Boerner, Yu Shyr, Derek Shyr, Mary Jo Pilat, Kristina Fanucci
Representativeness of Study Participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0df51c6bc3f4ac79ca4a3c83d4e7c11
https://doi.org/10.1158/2767-9764.22545912.v1
https://doi.org/10.1158/2767-9764.22545912.v1
Autor:
Patricia LoRusso, Antonio Omuro, Ranjit S. Bindra, S. Percy Ivy, Pierre Giglio, Javier Gonzalez, Frank Scott Lieberman, Vinay Puduvalli, Jan Drappatz, Diane Durecki, Jing Li, Scott Boerner, Yu Shyr, Derek Shyr, Mary Jo Pilat, Kristina Fanucci
Definition of Progression, Tumor Classification, and Eligibility Criteria, retreatment criteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38051cb61c7f9e35bbffa7887c372133
https://doi.org/10.1158/2767-9764.22545915
https://doi.org/10.1158/2767-9764.22545915
Autor:
Ingo K. Mellinghoff, Timothy F. Cloughesy, Minesh P. Mehta, Paul S. Mischel, John G. Kuhn, William H. Yong, Lisa M. DeAngelis, Andrew B. Lassman, Nian Wu, Steve Horvath, Howard A. Fine, Michael D. Prados, Susan M. Chang, Kathleen R. Lamborn, Patrick Y. Wen, Jan Drappatz, David A. Reardon, Mark R. Gilbert, W. K. Alfred Yung, Frank Lieberman, Linda M. Liau, Adriana Heguy, Cameron W. Brennan, Alicia Pedraza, Julie Dang, Daisuke Kuga, Akio Iwanami, Shaojun Zhu, Hui Tao, Nicolas Yannuzzi, Milan G. Chheda, Barbara Oldrini, Sara Kubek, Phioanh Leia Nghiemphu, Christian Grommes, Carl Campos, Daniel Rohle, H. Ian Robins, Igor Vivanco
mp3 file (11 MB). In the May edition of the Cancer Discovery podcast, Science Writer Elizabeth McKenna talks with Ingo K. Mellinghoff about his paper, which suggests that the disappointing clinical activity of first-generation EGFR inhibitors in glio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ea84dde1575a2f19855b3499939fbe
https://doi.org/10.1158/2159-8290.22529031.v1
https://doi.org/10.1158/2159-8290.22529031.v1
Autor:
Ingo K. Mellinghoff, Timothy F. Cloughesy, Minesh P. Mehta, Paul S. Mischel, John G. Kuhn, William H. Yong, Lisa M. DeAngelis, Andrew B. Lassman, Nian Wu, Steve Horvath, Howard A. Fine, Michael D. Prados, Susan M. Chang, Kathleen R. Lamborn, Patrick Y. Wen, Jan Drappatz, David A. Reardon, Mark R. Gilbert, W. K. Alfred Yung, Frank Lieberman, Linda M. Liau, Adriana Heguy, Cameron W. Brennan, Alicia Pedraza, Julie Dang, Daisuke Kuga, Akio Iwanami, Shaojun Zhu, Hui Tao, Nicolas Yannuzzi, Milan G. Chheda, Barbara Oldrini, Sara Kubek, Phioanh Leia Nghiemphu, Christian Grommes, Carl Campos, Daniel Rohle, H. Ian Robins, Igor Vivanco
PDF file - 689K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025f5ec99aaea9c2cde7f69d10999a40
https://doi.org/10.1158/2159-8290.22529022
https://doi.org/10.1158/2159-8290.22529022