Zobrazeno 1 - 10
of 567
pro vyhledávání: '"Jan, Buer"'
Autor:
Alexander Brehmer, Christopher Martin Sauer, Jayson Salazar Rodríguez, Kelsey Herrmann, Moon Kim, Julius Keyl, Fin Hendrik Bahnsen, Benedikt Frank, Martin Köhrmann, Tienush Rassaf, Amir-Abbas Mahabadi, Boris Hadaschik, Christopher Darr, Ken Herrmann, Susanne Tan, Jan Buer, Thorsten Brenner, Hans Christian Reinhardt, Felix Nensa, Michael Gertz, Jan Egger, Jens Kleesiek
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e55148 (2024)
BackgroundFHIR (Fast Healthcare Interoperability Resources) has been proposed to enable health data interoperability. So far, its applicability has been demonstrated for selected research projects with limited data. ObjectiveThis study aimed to desi
Externí odkaz:
https://doaj.org/article/0249c2cccc2c4bb79e6382070c8db9fa
Autor:
Philine Steinbach, Eva Pastille, Lara Kaumanns, Alexandra Adamczyk, Kathrin Sutter, Wiebke Hansen, Ulf Dittmer, Jan Buer, Astrid M Westendorf, Torben Knuschke
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011982 (2024)
Influenza A virus (IAV) can cause severe respiratory infection leading to significant global morbidity and mortality through seasonal epidemics. Likewise, the constantly increasing number of cancer diseases is a growing problem. Nevertheless, the und
Externí odkaz:
https://doaj.org/article/a63e2a8e22f64398969f9161ce87c646
Autor:
Hanna Abberger, Matthias Hose, Anne Ninnemann, Christopher Menne, Mareike Eilbrecht, Karl S Lang, Kai Matuschewski, Robert Geffers, Josephine Herz, Jan Buer, Astrid M Westendorf, Wiebke Hansen
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011837 (2023)
Neuropilin-1 (Nrp-1) expression on CD8+ T cells has been identified in tumor-infiltrating lymphocytes and in persistent murine gamma-herpes virus infections, where it interferes with the development of long-lived memory T cell responses. In parasitic
Externí odkaz:
https://doaj.org/article/7b59caa70b0d472fb4113dc9f186b875
Autor:
Willem Buys, Alexandra Bick, Rabea J. Madel, Astrid M. Westendorf, Jan Buer, Frank Herbstreit, Carsten J. Kirschning, Jürgen Peters
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionEarly sepsis is a life-threatening immune dysregulation believed to feature a “cytokine storm” due to activation of pattern recognition receptors by pathogen and danger associated molecular patterns. However, treatments with single to
Externí odkaz:
https://doaj.org/article/0f6bd744994d4ebcab332f1c92080099
Autor:
Elias Haj-Yehia, Sebastian Korste, Robert Jochem, Aldona Lusha, Anna Roth, Nina Dietzel, Josefine Niroomand, Pia Stock, Astrid M. Westendorf, Jan Buer, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Totzeck
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 48, Iss , Pp 101269- (2023)
CD47 is a cell surface protein controlling phagocytotic activity of innate immune cells. CD47 blockade was investigated as an immune checkpoint therapy in cancer treatment, enhancing phagocytosis of tumor cells by macrophages. Anti-CD47 treatment als
Externí odkaz:
https://doaj.org/article/3e38543a33e249afba3fe9903646b023
Autor:
Jan Kehrmann, Fiona Koch, Skrollan Zumdick, Anna Höwner, Lara Best, Lars Masshöfer, Sarah Scharfenberg, Michael Zeschnigk, Jürgen C. Becker, Dirk Schadendorf, Jan Buer, Alexander Roesch
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Skin microbiome dysbiosis with a Staphylococcus overabundance is a feature of actinic keratosis (AK) and squamous skin carcinoma (SCC) patients. The impact of lesion-directed treatments for AK lesions such as diclofenac (DIC) and cold atmosp
Externí odkaz:
https://doaj.org/article/f0f850ffb9a24c61835eb0604fdcedde
Autor:
Amir A. Mahabadi, Raluca Mincu, Iryna Dykun, Lars Michel, Alexander Küng, Oliver Witzke, Clemens Kill, Jan Buer, Tienush Rassaf, Matthias Totzeck
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 45, Iss , Pp 101184- (2023)
Background: The COVID-19 pandemic led to an alteration of algorithms in emergency medicine, which may influence the management of patients with similar symptoms but underlying cardiovascular diseases. We evaluated key differential diagnoses to acute
Externí odkaz:
https://doaj.org/article/1863dd1034124b148c2cc5d1150c5149
Autor:
Christina Wenzek, Philine Steinbach, Florian Wirsdörfer, Kathrin Sutter, Julia D. Boehme, Robert Geffers, Robert Klopfleisch, Dunja Bruder, Verena Jendrossek, Jan Buer, Astrid M. Westendorf, Torben Knuschke
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105540- (2022)
Summary: CD47 is an ubiquitously expressed surface molecule with significant impact on immune responses. However, its role for antiviral immunity is not fully understood. Here, we revealed that the expression of CD47 on immune cells seemed to disturb
Externí odkaz:
https://doaj.org/article/13de89e0b0ca48f9bd746945964e9b6d
Autor:
Matthias Hose, Anne Günther, Eyad Naser, Fabian Schumacher, Tina Schönberger, Julia Falkenstein, Athanasios Papadamakis, Burkhard Kleuser, Katrin Anne Becker, Erich Gulbins, Adriana Haimovitz-Friedman, Jan Buer, Astrid M Westendorf, Wiebke Hansen
Publikováno v:
eLife, Vol 11 (2022)
Acid sphingomyelinase (Asm) and acid ceramidase (Ac) are parts of the sphingolipid metabolism. Asm hydrolyzes sphingomyelin to ceramide, which is further metabolized to sphingosine by Ac. Ceramide generates ceramide-enriched platforms that are involv
Externí odkaz:
https://doaj.org/article/e8451a73e0d644448fa86305cbe73999
Autor:
Anne Günther, Matthias Hose, Hanna Abberger, Fabian Schumacher, Ylva Veith, Burkhard Kleuser, Kai Matuschewski, Karl Sebastian Lang, Erich Gulbins, Jan Buer, Astrid M Westendorf, Wiebke Hansen
Publikováno v:
eLife, Vol 11 (2022)
Acid ceramidase (Ac) is part of the sphingolipid metabolism and responsible for the degradation of ceramide. As bioactive molecule, ceramide is involved in the regulation of many cellular processes. However, the impact of cell-intrinsic Ac activity a
Externí odkaz:
https://doaj.org/article/d7bfdd0ec15f450d8112fb8ebc0a7fda