Zobrazeno 1 - 10
of 353
pro vyhledávání: '"Jan, Baumbach"'
Autor:
Kristopher Nolte, Felix Gregor Sauer, Jan Baumbach, Philip Kollmannsberger, Christian Lins, Renke Lühken
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract Mosquito-borne diseases are a major global health threat. Traditional morphological or molecular methods for identifying mosquito species often require specialized expertise or expensive laboratory equipment. The use of convolutional neural
Externí odkaz:
https://doaj.org/article/c56364a1ee2d460d8bb977e2690418ee
Autor:
Alissa Brauneck, Louisa Schmalhorst, Stefan Weiss, Linda Baumbach, Uwe Völker, David Ellinghaus, Jan Baumbach, Gabriele Buchholtz
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Genomic data holds huge potential for medical progress but requires strict safety measures due to its sensitive nature to comply with data protection laws. This conflict is especially pronounced in genome-wide association studies (GWAS) whic
Externí odkaz:
https://doaj.org/article/02cc3e4eaf884272bb38bfbc66c04ad2
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110081- (2024)
Summary: The reproductive phase of plants is highly sensitive to ambient temperature stresses. To investigate sensitivity of female reproductive organs in grass crops during the pollination phase, we exposed the elongated stigma (silk) of maize to am
Externí odkaz:
https://doaj.org/article/c07bae7a24d34f3c96ecc2d83ebc6a4b
Autor:
Markus Hoffmann, Lina-Liv Willruth, Alexander Dietrich, Hye Kyung Lee, Ludwig Knabl, Nico Trummer, Jan Baumbach, Priscilla A. Furth, Lothar Hennighausen, Markus List
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Bulk RNA sequencing (RNA-seq) of blood is typically used for gene expression analysis in biomedical research but is still rarely used in clinical practice. In this study, we propose that RNA-seq should be considered a diagnostic tool, as it
Externí odkaz:
https://doaj.org/article/8467cfc803f64d2c807e7f55678a08f9
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 2, Pp 257-269 (2024)
Abstract High drug development costs and the limited number of new annual drug approvals increase the need for innovative approaches for drug effect prediction. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the cause of coronaviru
Externí odkaz:
https://doaj.org/article/5665341e05e443b1b2a22a646829cd71
Autor:
Klaudia Adamowicz, Lis Arend, Andreas Maier, Johannes R. Schmidt, Bernhard Kuster, Olga Tsoy, Olga Zolotareva, Jan Baumbach, Tanja Laske
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Proteomics technologies, which include a diverse range of approaches such as mass spectrometry-based, array-based, and others, are key technologies for the identification of biomarkers and disease mechanisms, referred to as mechanotyping. De
Externí odkaz:
https://doaj.org/article/4b2ab75f8e404e708760f72bb3c8d516
Autor:
Alissa Brauneck, Louisa Schmalhorst, Stefan Weiss, Linda Baumbach, Uwe Völker, David Ellinghaus, Jan Baumbach, Gabriele Buchholtz
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/05c7fe3008924be3a31d211f6f8c518c
Autor:
Aylin Del Moral-Morales, Cynthia Sámano, José Antonio Ocampo-Cervantes, Maya Topf, Jan Baumbach, Jossephlyn Hernández, Karla Torres-Arciga, Rodrigo González-Barrios, Ernesto Soto-Reyes
Publikováno v:
Scientifica, Vol 2024 (2024)
The axolotl, known for its remarkable regenerative abilities, is an excellent model for studying regenerative therapies. Nevertheless, the precise molecular mechanisms governing its regenerative potential remain uncertain. In this study, we collected
Externí odkaz:
https://doaj.org/article/139479b2aa214f03a9855a6a545e153b
Autor:
Sepideh Sadegh, James Skelton, Elisa Anastasi, Andreas Maier, Klaudia Adamowicz, Anna Möller, Nils M. Kriege, Jaanika Kronberg, Toomas Haller, Tim Kacprowski, Anil Wipat, Jan Baumbach, David B. Blumenthal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Large-scale disease-association data are widely used for pathomechanism mining, even if disease definitions used for annotation are mostly phenotype-based. Here, the authors show that this bias can lead to a blurred view on disease mechanisms, highli
Externí odkaz:
https://doaj.org/article/f94efe6e0688493fa30f8c9113b32eb9
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 780-795 (2023)
Molecular interaction networks lay the foundation for studying how biological functions are controlled by the complex interplay of genes and proteins. Investigating perturbed processes using biological networks has been instrumental in uncovering mec
Externí odkaz:
https://doaj.org/article/697a5d5aa0de4033a0c14a4c40b30a15