Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jamshid Davoodi"'
Publikováno v:
Cell Journal, Vol 23, Iss 6, Pp 674-683 (2021)
Objective: Alimta (Pemetrexed) as an antifolate drug has been approved for the treatment of lung cancer. The aim of the present study was to investigate the combination effect of 5-Azacytidine (5-aza) and Alimta on the miR-34a and its target genes ex
Externí odkaz:
https://doaj.org/article/9f5ac4074ad84cfaa227c9deb2047963
Autor:
Loghman Firoozpour, Lixin Gao, Setareh Moghimi, Parvin Pasalar, Jamshid Davoodi, Ming-Wei Wang, Zahra Rezaei, Armin Dadgar, Hoda Yahyavi, Massoud Amanlou, Alireza Foroumadi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1674-1684 (2020)
In this paper, a new series of isatin-sulphonamide based derivatives were designed, synthesised and evaluated as caspase inhibitors. The compounds containing 1-(pyrrolidinyl)sulphonyl and 2-(phenoxymethyl)pyrrolidin-1-yl)sulphonyl substitution at C5
Externí odkaz:
https://doaj.org/article/19ec5e7518364f56b034dc21514ae3ab
Publikováno v:
Biochemical and Biophysical Research Communications. 655:138-144
Autor:
Zohreh Jahani, Jamshid Davoodi
Publikováno v:
Biochemical and Biophysical Research Communications. 629:71-77
Anti-diabetic drug, metformin, has attracted attentions as an anti-cancer agent due to the suppression of mTORC1 as a master switch of cell growth in various cancers. Upon mTORC1 inhibition, translation of proteins possessing IRES elements in their m
Publikováno v:
Preparative Biochemistry & Biotechnology. 50:723-734
Herein, we describe a simple and efficient approach to produce recombinant human α-synuclein (hAS) with high purity from Escherichia coli (E. coli). The cDNA for hAS was inserted into plasmid pET32...
Publikováno v:
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials. 76:85-92
Due to the inherent geometrical interdependencies of nucleic acid structures, the ability to engineer biosensors that rely on the specific interactions of these compounds is of considerable importance. Additionally, sensing or screening in a label-fr
Autor:
Setareh Moghimi, Jamshid Davoodi, Massoud Amanlou, Ming-Wei Wang, Loghman Firoozpour, Alireza Foroumadi, Hoda Yahyavi, Parvin Pasalar, Lixin Gao, Zahra Rezaei, Armin Dadgar
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1674-1684 (2020)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
ABTRACT In this paper, a new series of isatin-sulphonamide based derivatives were designed, synthesised and evaluated as caspase inhibitors. The compounds containing 1-(pyrrolidinyl)sulphonyl and 2-(phenoxymethyl)pyrrolidin-1-yl)sulphonyl substitutio
Publikováno v:
Biochimie. 190
Deregulation of apoptosis is associated with various pathologies, such as neurodegenerative disorders at one end of the spectrum and cancer at the other end. Generally speaking, differentiated cells like cardiomyocytes, skeletal myocytes and neurons
Autor:
Gholam Hossein Riazi, Jamshid Davoodi, Loghman Firoozpour, Mohammad Taheri, Shayan Abbasi, Sama Pirkalkhoran, Homa Farahani, Hossein Lanjanian, Shahriar Pooyan
Publikováno v:
Bioconjugate chemistry. 31(3)
The attachment of PEG to biopharmaceuticals has been applied for enhancement of bioavailability and improved stability. The PEG polymer is highly hydrated; thus effective attachment to inaccessible sites could be hindered. We have devised a scheme to
Autor:
Ali Akbar Saboury, Fatemeh Mamashli, Shayan Abbasi, Gholam Hossein Riazi, Leila Shahriyary, Mohammad Reza Lornejad, Jamshid Davoodi, Bahareh Bigdeli, Behdad Delavari, Mansoureh Ghezlou
Publikováno v:
Archives of Biochemistry and Biophysics. 647:54-66
Altered blood-brain barrier (BBB) permeability may contribute to pathogenesis of diabetes-related central nervous system disorders. Considering the presence of glycated insulin in plasma of type 2 diabetic patients, we hypothesized that glycated insu