Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Jamil S. Saad"'
Autor:
Lei Zhang, James E. Kent, Meredith Whitaker, David C. Young, Dominik Herrmann, Alexander E. Aleshin, Ying-Hui Ko, Gino Cingolani, Jamil S. Saad, D. Branch Moody, Francesca M. Marassi, Sabine Ehrt, Michael Niederweis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The pathogen Mycobacterium tuberculosis uses the siderophores called mycobactins and carboxymycobactins to acquire iron from the host. Here, Zhang et al. identify a protein that is important for siderophore secretion and for the pathogen’s growth i
Externí odkaz:
https://doaj.org/article/251ba6d7e8674c55b91f689c769c3dd9
Autor:
Terry Brissac, Eriel Martínez, Katherine L. Kruckow, Ashleigh N. Riegler, Feroze Ganaie, Hansol Im, Sayan Bakshi, Nicole M. Arroyo-Diaz, Brady L. Spencer, Jamil S. Saad, Moon H. Nahm, Carlos J. Orihuela
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Streptococcus pneumoniaeSpnSpn
Externí odkaz:
https://doaj.org/article/9ce4442b4bb54ebd8049a3b39250c14b
Autor:
Feroze Ganaie, Jamil S. Saad, Lesley McGee, Andries J. van Tonder, Stephen D. Bentley, Stephanie W. Lo, Rebecca A. Gladstone, Paul Turner, Jeremy D. Keenan, Robert F. Breiman, Moon H. Nahm
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Streptococcus pneumoniae (pneumococcus) is a major human pathogen producing structurally diverse capsular polysaccharides. Widespread use of highly successful pneumococcal conjugate vaccines (PCVs) targeting pneumococcal capsules has greatly
Externí odkaz:
https://doaj.org/article/ace5de8408464a8cb058b6df08a8c82e
Autor:
R. Elliot Murphy, Alexandra B. Samal, Gunnar Eastep, Ruba H. Ghanam, Peter E. Prevelige, Jamil S. Saad
Publikováno v:
Proceedings, Vol 50, Iss 1, p 114 (2020)
During the late phase of the HIV-1 replication cycle, the Gag polyproteins are transported to the plasma membrane (PM) for assembly. Gag targeting and assembly on the PM is dependent on interactions between its matrix (MA) domain and phosphatidylinos
Externí odkaz:
https://doaj.org/article/0e7bae4d392b4dafbcb13e85f3a223d3
Autor:
R. Elliot Murphy, Jamil S. Saad
Publikováno v:
Viruses, Vol 12, Iss 5, p 548 (2020)
Advancement in drug therapies and patient care have drastically improved the mortality rates of HIV-1 infected individuals. Many of these therapies were developed or improved upon by using structure-based techniques, which underscore the importance o
Externí odkaz:
https://doaj.org/article/fadf29081ad147978dca9374581a07e9
Autor:
Feroze A. Ganaie, Jamil S. Saad, Stephanie W. Lo, Lesley McGee, Stephen D. Bentley, Andries J. van Tonder, Paulina Hawkins, Jeremy D. Keenan, Juan J. Calix, Moon H. Nahm
Publikováno v:
Journal of Clinical Microbiology. 61
Streptococcus pneumoniae can produce a wide breadth of antigenically diverse capsule types, a fact that poses a looming threat to the success of vaccines that target pneumococcal polysaccharide (PS) capsule. Yet, many pneumococcal capsule types remai
Publikováno v:
Proceedings of the National Academy of Sciences. 119
During the late phase of HIV type 1 (HIV-1) infection cycle, the virally encoded Gag polyproteins are targeted to the inner leaflet of the plasma membrane (PM) for assembly, formation of immature particles, and virus release. Gag binding to the PM is
Autor:
Dominik Herrmann, Heather M. Hanson, Lynne W. Zhou, Rayna Addabbo, Nora A. Willkomm, Isaac Angert, Joachim D. Mueller, Louis M. Mansky, Jamil S. Saad
Publikováno v:
Journal of molecular biology. 434(12)
Assembly of human T-cell leukemia virus type 1 (HTLV-1) particles is initiated by the trafficking of virally encoded Gag polyproteins to the inner leaflet of the plasma membrane (PM). Gag-PM interactions are mediated by the matrix (MA) domain, which
Autor:
Carlos J. Orihuela, Eriel Martínez, Moon H. Nahm, Hansol Im, Jennifer N Luck, Feroze Ganaie, Jamil S. Saad, Hervé Tettelin, Katherine L Kruckow, Ashleigh N. Riegler, Xiuhong Song, Adonis D'Mello, Elie Ghanem, Kyle H. Cichos
Publikováno v:
Infect Immun
Streptococcus pneumoniae colonizes the nasopharynx asymptomatically but can also cause severe life-threatening disease. Importantly, stark differences in carbohydrate availability exist between the nasopharynx and invasive disease sites, such as the