Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jamil Momand"'
Autor:
Jamil Momand, Patrycja Magdziarz, You Feng, Dianlu Jiang, Elizabeth Parga, Arianna Celis, Erin Denny, Xiaoying Wang, Martin L. Phillips, Estuardo Monterroso, Susan E. Kane, Feimeng Zhou
Publikováno v:
FEBS Open Bio, Vol 7, Iss 9, Pp 1328-1337 (2017)
t‐Darpp (truncated isoform of dopamine‐ and cAMP‐regulated phosphoprotein) is a protein encoded by the PPP1R1B gene and is expressed in breast, colon, esophageal, gastric, and prostate cancers, as well as in normal adult brain striatal cells. O
Externí odkaz:
https://doaj.org/article/12145b9857474e3386f4d4e5b62d0d49
Publikováno v:
Case Reports in Oncological Medicine, Vol 2015 (2015)
We describe the presentation, treatment, clinical outcome, and targeted genome analysis of a metastatic salivary acinic cell carcinoma (AciCC). A 71-year-old male presented with a 3 cm right tail of a parotid lesion, first detected as a nodule by the
Externí odkaz:
https://doaj.org/article/c63c3ff570b64821a1360dafec860f14
Autor:
Janice M. Huss, Susan E. Kane, Jamil Momand, Markus Kalkum, Teresa Hong, Shuhui Geng, Angelica Hamilton, Gal Lenz
Table S1. Co-occurrence analysis of PPP1R1B and IGF-1R transcripts Table S2. Hazard ratios associated with PPP1R1B and IGF-1R expression Table S3. Multivariate analysis of PPP1R1B and IGF-1R with HER2 for OS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e53be5ad4de6c78bd01e35cecf8f3bf
https://doi.org/10.1158/1078-0432.22464455.v1
https://doi.org/10.1158/1078-0432.22464455.v1
Autor:
Janice M. Huss, Susan E. Kane, Jamil Momand, Markus Kalkum, Teresa Hong, Shuhui Geng, Angelica Hamilton, Gal Lenz
Figure S1. Protein levels of PPP1R1B and IGF-1R. Figure S2. Comparison of respiration rates in SK-BR-3 parental and derived cell lines. Figure S3. siRNA knockdown of IGF-1R and IR. Figure S4. The effect of recombinant t-Darpp on oxygen consumption ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9635ebb041d768c87abc8b0840f1bb
https://doi.org/10.1158/1078-0432.22464461.v1
https://doi.org/10.1158/1078-0432.22464461.v1
Autor:
Janice M. Huss, Susan E. Kane, Jamil Momand, Markus Kalkum, Teresa Hong, Shuhui Geng, Angelica Hamilton, Gal Lenz
Purpose: Increased glycolysis and glucose dependence is a hallmark of malignancy that enables tumors to maximize cell proliferation. In HER2+ cancers, an increase in glycolytic capacity is associated with trastuzumab resistance. IGF-1R activation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce98ba32c1e12ae330c21ef4bed3b0a
https://doi.org/10.1158/1078-0432.c.6525725
https://doi.org/10.1158/1078-0432.c.6525725
Autor:
Narek Darabedian, Feimeng Zhou, Ernest Enriquez, Jamil Momand, Wang Zhao, Patrycja Magdziarz, Xiaoying Wang, Chris Quan
Publikováno v:
Analytical Biochemistry. 569:53-58
Docking on the p53-binding site of murine double minute 2 (MDM2) by small molecules restores p53's tumor-suppressor function. We previously assessed 3244 FDA-approved drugs via “computational conformer selection” for inhibiting MDM2 and p53 inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b732e71e558033536f0e481ac5f85501
https://doi.org/10.1016/j.ab.2019.01.012
https://doi.org/10.1016/j.ab.2019.01.012
Publikováno v:
Biochemical Pharmacology. 160:71-79
The PPP1R1B gene is located on chromosome 17q12 (39,626,208–39,636,626[GRCh38/hg38]), which codes for multiple transcripts and two experimentally-documented proteins Darpp-32 and t-Darpp. Darpp-32 (Dopamine and cAMP Regulated Phosphoprotein), disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2aa2f34b460189c7c7ac5fc4d63de2
https://doi.org/10.1016/j.bcp.2018.12.008
https://doi.org/10.1016/j.bcp.2018.12.008
Autor:
Jamil Momand, Anureet K. Shah
Publikováno v:
Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications ISBN: 9789811651045
Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications
Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd85e8bed616e24363b1407b30441dd2
https://doi.org/10.1007/978-981-16-5105-2_16
https://doi.org/10.1007/978-981-16-5105-2_16
Publikováno v:
Gene. 799
We set out to uncover transcriptome and chromatin landscape changes that occur in HER2 + breast cancer (BC) cells upon acquiring resistance to trastuzumab. RNA-seq analysis was applied to two independently-derived BC cell lines with acquired resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1676d2d0886316fd24009336ba22ea50
https://pubmed.ncbi.nlm.nih.gov/34224831
https://pubmed.ncbi.nlm.nih.gov/34224831